Patents by Inventor Guy P. A. Vigers

Guy P. A. Vigers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF PHOSPHATASES
    Publication number: 20090060968
    Abstract: The present invention relates to compounds that inhibit phosphatases, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Application
    Filed: September 12, 2008
    Publication date: March 5, 2009
    Inventors: Jeffrey O. Saunders, Gregory F. Miknis, Alexandre J. Buckmelter, Kevin W. Hunt, James F. Blake, Guy P.A. Vigers, Xicheng Sun
  • Inhibitors of phosphatases
    Patent number: 7439249
    Abstract: The present invention relates to compounds that inhibit phosphatases, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: October 21, 2008
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Jeffrey O. Saunders, Gregory F. Miknis, Alexandre J. Buckmelter, Kevin W. Hunt, James F. Blake, Guy P. A. Vigers, Xicheng Sun
  • Method of structure-based drug design to create or improve modulators of IL-1 activity which bind to the interleukin-1 type 1 receptor
    Patent number: 7144988
    Abstract: Crystals comprising a modified interleukin-1 type 1 receptor (IL-1R1) and one or more modulators of IL-1 activity are described. Methods of identifying potential inhibitors of IL-1 activity are also described. Compositions and methods for the treatment of IL-1 mediated diseases, such as rheumatoid arthritis, osteoarthritis, and other inflammatory conditions, are described.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: December 5, 2006
    Assignee: Array Biopharma, Inc.
    Inventors: Barbara J. Brandhuber, Guy P. A. Vigers
  • Inhibitors of phosphatases
    Publication number: 20040186116
    Abstract: The present invention relates to compounds that inhibit phosphatases, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Application
    Filed: December 31, 2003
    Publication date: September 23, 2004
    Inventors: Jeffrey O. Saunders, Gregory F. Miknis, Alexandre J. Buckmelter, Kevin W. Hunt, James F. Blake, Guy P.A. Vigers, Xicheng Sun
  • Method of structure-based drug design to create or improve modular of IL-1 activity which mind to the interleukin-1 type 1 receptor
    Publication number: 20040014643
    Abstract: Crystals comprising a modified interleukin-1 type 1 receptor (IL-1R1) and one or more modulators of IL-1 activity are described. Methods of identifying potential inhibitors of IL-1 activity are also described. Compositions and methods for the treatment of IL-1 mediated diseases, such as rheumatoid arthritis, osteoarthritis, and other inflammatory conditions, are described.
    Type: Application
    Filed: March 14, 2003
    Publication date: January 22, 2004
    Applicant: Array BioPharma Inc.
    Inventors: Barbara J. Brandhuber, Guy P.A. Vigers