Patents by Inventor Guy P. Adrian

Guy P. Adrian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5019655
    Abstract: Method of preparing 4-disubstituted phenyl-1-tetralones of formula ##STR1## in which X represents halogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy and Y, situated in position 2' or 3', represents halogen or C.sub.1 -C.sub.4 alkyl, this method being characterized in that it comprises the reaction, in the presence of an acid agent, of .alpha.-naphthol of formula (II) with a phenyl compound of formula (III): ##STR2## where X represents halogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, and Y is situated in the ortho or meta position with respect to X and represents halogen or C.sub.1 -C.sub.4 alkyl.
    Type: Grant
    Filed: June 8, 1989
    Date of Patent: May 28, 1991
    Assignee: Delalande S.A.
    Inventor: Guy P. Adrian
  • Patent number: 4739100
    Abstract: The present invention provides a process for preparing 6-(lower)alkoxy-1-naphthoic acids, the corresponding esters and 5-halo substituted derivatives thereof. The process comprises reacting furoic acid with an alkoxyphenyl compound, followed by acid hydrolysis to form a mixture of alkoxy and hydroxy substituted naphthoic acids, subjecting said mixture to the action of an alkylating agent, and optionally further treating the alkylated product to another hydrolysis step or a halogenation step.
    Type: Grant
    Filed: September 27, 1985
    Date of Patent: April 19, 1988
    Assignee: Delalande S.A.
    Inventors: Guy P. Adrian, Sylvain G. Garnier
  • Patent number: 4667056
    Abstract: A process for preparing hydratropic acids and the esters thereof, of formula Ar--CH(CH.sub.3)--COOR where R=H or lower alkyl and Ar=phenyl possibly substituted. This process consists in reacting on the propiophenones of formula ArCOCH.sub.2 CH.sub.3, a chlorinating or brominating agent, an alcohol R'OH where R'=lower alkyl, an orthoester R.sub.1 --C(OR').sub.3 wherein R.sub.1 =H or lower alkyl, and metal zinc; then possibly hydrolyzing the esters obtained.With this process can be prepared hydratropic acids known for their anti-inflammatory activity.
    Type: Grant
    Filed: May 3, 1985
    Date of Patent: May 19, 1987
    Assignee: Delalande S.A.
    Inventor: Guy P. Adrian