Patents by Inventor Guy R. Bourgery

Guy R. Bourgery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4153620
    Abstract: Aminoalkoxybenzofurans having the formula ##STR1## wherein ##STR2## are either (1) ##STR3## is monoalkylamino, dialkylamino, cycloalkylamino or heterocyclic amino, or (2) ##STR4## (H, 1, 4-methyl piperazino), ##STR5## is piperidino. The compounds possess antidysrhythmic properties.
    Type: Grant
    Filed: June 12, 1978
    Date of Patent: May 8, 1979
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Alain P. Lacour, Bernard M. Pourrias, Genevieve C. Bregeon
  • Patent number: 4150029
    Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or CONHR.sub.7 and R.sub.7 is methyl or isopropyl,And whereinWhen R.sub.1 is hydrogen: R is p-nitro, p-cyano; p-aldehydo; p-acetyl; m-ethyl; m-nitro; m-bromo; 3,4-dimethyl; m-NH.sub.2 ; p-methylamino; p-dimethylamino; p-diethylamino; p-methylbenzylamino; p-pyrrolidino; p-piperidino; SR.sub.4 in para position in which R.sub.4 is alkyl having 1 to 4 carbon atoms or cyclohexyl; OR.sub.5 is para position in which R.sub.5 is alkyl having 2 to 7 carbon atoms, cyclohexyl, cyclohexylmethyl, acetylmethyl; cyanomethyl, alkene-2 yl having 3 to 5 carbon atoms, butene-3 yl, cyclohexene-1 methyl, propargyl, butyne-2 yl, ##STR2## in which n is one or 2 and when n is one, R.sub.6 is hydrogen, o-fluoro, o-methyl, m-chloro, m-fluoro, m-methyl, m-trifluoromethyl, p-chloro, p-bromo-, p-fluoro, p-cyano, p-nitro or p-dimethylamino and when n is 2, R.sub.6 is hydrogen; and 3-methyl-4-benzyloxy:When R.sub.1 is CONHR.sub.7 and R.sub.
    Type: Grant
    Filed: February 23, 1977
    Date of Patent: April 17, 1979
    Assignee: Delalande S.A.
    Inventors: Philippe L. Dostert, Colette A. Douzon, Guy R. Bourgery, Claude J. Gouret, Gisele C. Mocquet, Jean A. Coston
  • Patent number: 4113951
    Abstract: Aminoalkoxybenzofurans having the formula ##STR1## wherein ##STR2## are either (1) ##STR3## and ##STR4## is monoalkylamino, dialkylamino, cycloalkylamino or heterocyclic amino, or (2) ##STR5## (H, 1, 4-methyl piperazino), ##STR6## is piperidino. The compounds possess antidysrhythmic properties.
    Type: Grant
    Filed: July 6, 1977
    Date of Patent: September 12, 1978
    Assignee: Delalande S. A.
    Inventors: Guy R. Bourgery, Alain P. Lacour, Bernard M. Pourrias, Genevieve C. Bregeon
  • Patent number: 4061855
    Abstract: Compounds of the formula ##STR1## IN WHICH R is aminocarbonylphenyl in which amino is --NH.sub.2, pyrrolidino, piperidino or morpholino, and Ar is phenyl substituted with chloro, fluoro, trifluoromethyl, methylenedioxy or one or more methoxy. The compounds are prepared by reacting 2-Ar-4-chloropyrimidin-6-yl ethylacetate with ##STR2## and then reacting that reaction product with hydroxylamine hydrochloride. The compounds possess vasodilatatory, anti-ulcerous, respiratory analeptic, hypotensive, diuretic, anti-depressive, analgesic, anti-inflammatory and neurotropic properties.
    Type: Grant
    Filed: December 10, 1976
    Date of Patent: December 6, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Jeannine A. Eberle, Guy R. Bourgery, Guy R. Raynaud, Claude J. Gouret
  • Patent number: 4041072
    Abstract: Compounds having the formula ##STR1## wherein R is hydrogen, or chlorine, or alkyl having one to 4 carbons, or alkoxy having one to 3 carbons, and R.sub.1 is hydrogen, or ##STR2## or --CONH--R.sub.3, wherein R.sub.2 is hydrogen, or chlorine, or nitro, or alkoxy having no more than 3 carbons, or trifluoromethyl, and R.sub.3 is alkyl having one to 4 carbons, or cycloalkyl having no more than 6 carbons, or phenyl.The compounds are prepared by reacting R-substituted cyano-2 acetanilides with hydroxylamine to obtain compounds in which R.sub.1 is hydrogen, and then reacting with acid chlorides containing R.sub.2 or isocyanates containing R.sub.3. The compounds possess psychtropic properties.
    Type: Grant
    Filed: March 18, 1976
    Date of Patent: August 9, 1977
    Assignee: Delalande S. A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Claude J. Gouret
  • Patent number: 4041030
    Abstract: Compounds of the formula ##STR1## WHEREIN Ar is phenyl or phenyl substituted by one or more halogens, a trifluoromethyl, a methylenedioxy, one or more methoxy, an alkyl having one to 4 carbon atoms or a dimethylamino,And R is ##STR2## wherein R.sub.1 and R.sub.2 each are hydrogen or alkyl of 1 to 4 carbon atoms, or ##STR3## PYRROLIDINO, MORPHOLINO, PIPERIDINO OR PIPERAZINO N'-substituted by alkyl of 1 to 4 carbon atoms, or phenyl, or R is para-2-morpholino ethylamino carbonyl, and R.sub.3 is hydrogen or methyl.The compounds are obtained by reacting 2-Ar-2-chloro-6-methyl pyrimidine, with ##STR4## The compounds possess sedative, antiulcerous, antibronchoconstrictive, anticholinergic, diuretic, analgesic myorelaxant and antianoximia properties.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: August 9, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Guy M. Raynaud, Claude J. Gouret
  • Patent number: 4031089
    Abstract: Compounds of the formula ##STR1## wherein R is alkyl of 1-4 carbon atoms, phenyl, or phenyl substituted by one or more halogen or trifluoromethyl, and Z is ##STR2## wherein R.sub.1 is hydrogen, alkyl of 1-4C, 2,2-dimethyldioxolan-4-yl methyl, or 2,3-dihydroxy prop-1-yl, R.sub.2 is ##STR3## wherein ##STR4## is morpholino, pyrrolidino, piperidino or hexamethyleneimino, and n is an integer from 4 to 7.The compounds are prepared by reacting R-substituted 4-chloro-2-methyl furo (2,3d) pyrimidine with HZ. The compounds possess antiulcerous, antibronchoconstrictive and anticholinergic, analgesic, antihistamine, diuretic, cardiovascular analeptic, antiinflammatory and hypertensive properties.
    Type: Grant
    Filed: August 18, 1976
    Date of Patent: June 21, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Guy M. Raynaud, Nicole A. M. Dorme
  • Patent number: 4025514
    Abstract: Compounds of the formula ##STR1## wherein Ar is phenyl or phenyl substituted by one or more halogens, a trifluoromethyl, a methylenedioxy, one or more methoxy, an alkyl having one to 4 carbon atoms or a dimethylamino,And R is ##STR2## and R.sub.5 is alkyl of 1 to 4 carbon atoms, 2,3-dihydroxypropyl or 2,2-dimethyl dioxolan-4-yl methyl or hydroxycarbonylmethyl.The compounds are obtained by reacting 2-Ar-4-chloro-6-methyl pyrimidine, with ##STR3## The compounds possess sedative, antiinflammatory, antiulcerous, and anti-anoxemia properties.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: May 24, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Guy M. Raynaud, Claude J. Gouret
  • Patent number: 4013768
    Abstract: Compounds of the formula ##STR1## in which R is aminocarbonylphenyl in which amino is --NH.sub.2, pyrrolidino, piperidino or morpholino, and Ar is phenyl substituted with chloro, fluoro, trifluoromethyl, methylenedioxy or one or more methoxy.The compounds are prepared by 2-Ar-4-chloro-pyrimidin-6-yl ethylacetate with ##STR2## and then reacting that reaction product with hydroxylamine hydrochloride. The compounds possess vasodilatatory, anti-ulcerous, respiratory analeptic, hypotensive, diuretic, anti-depressive, analgesic, anti-inflammatory and neurotropic properties.
    Type: Grant
    Filed: March 3, 1975
    Date of Patent: March 22, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Jeannine A. Eberle, Guy R. Bourgery, Guy M. Raynaud, Claude J. Gouret
  • Patent number: 4007187
    Abstract: Compounds of the formula ##STR1## wherein R is alkyl of 1-4 carbon atoms, phenyl, or phenyl substituted by one or more halogen or trifluoromethyl, and Z is ##STR2## wherein R.sub.1 is hydrogen, alkyl of 1-4C, 2,2-dimethyldioxolan-4-yl methyl, or 2,3-dihydroxy prop-1-yl, R.sub.2 is ##STR3## wherein ##STR4## is morpholino, pyrrolidino, piperidino or hexamethyleneimino, and n is an integer from 4 to 7. The compounds are prepared by reacting R-substituted 4-chloro-2-methyl furo (2,3d) pyrimidine with HZ. The compounds possess antiulcerous, antibronchoconstrictive and anticholinergic, analgesic, antihistamine, diuretic, cardiovascular analeptic, antiinflammatory and hypertensive properties.
    Type: Grant
    Filed: September 17, 1974
    Date of Patent: February 8, 1977
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Guy M. Raynaud, Nicole A. M. Dorme
  • Patent number: 3978055
    Abstract: Compounds of the formula ##SPC1##Wherein Ar is phenyl or phenyl substituted by one or more halogens, by a trifluoromethyl or a methylenedioxy, by one or more methoxy, by an alkyl having one to 4 carbon atoms or by a dimethylamino,And R is ##EQU1## or --O-- ##EQU2## or ##EQU3## wherein R.sub.1 and R.sub.2 each are hydrogen or alkyl of 1 to 4 carbon atoms, or ##EQU4## is pyrrolidino, morpholino, piperidino or piperazino N'-substituted by alkyl of 1 to 4 carbon atoms, or phenyl; R.sub.3 and R.sub.4 each are alkyl of 1 to 3 carbon atoms or ##EQU5## is morpholino, pyrrolidino, piperidino or hexamethyleneimino, n is an integer of 1 to 5; and R.sub.5 is alkyl of 1 to 4 carbon atoms, 2,3-dihydroxypropyl or 2,2-dimethyl dioxolan-4-yl methyl or hydroxycarbonylmethyl.
    Type: Grant
    Filed: September 3, 1974
    Date of Patent: August 31, 1976
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Guy R. Bourgery, Guy M Raynaud, Claude J. Gouret
  • Patent number: 3971793
    Abstract: A compound of the formula ##SPC1##In which R is hydrogen, hydroxy, halogen or alkoxy containing up to 3 carbon atoms, and ##EQU1## is dialkylamino in which the alkyls contain up to 3 carbon atoms, or pyrrolidino, piperidino, morpholino or hexamethyleneimino, and n is 2 or 3. The compounds are prepared by reacting R substituted benzaldehyde with a 2,3-dihydrobenzofuran derivative and then reducing that reaction product. The compounds possess antihypertensive, hypotensive, vasodilatatory, spasmolytic, diuretic, sedative, anti-arythmic and anti-inflammatory properties.
    Type: Grant
    Filed: February 1, 1974
    Date of Patent: July 27, 1976
    Assignee: Delalande S.A.
    Inventors: Claude P. Fauran, Jeannine A. Eberle, Guy R. Bourgery, Guy M. Raynaud, Bernard M. Pourrias