Patents by Inventor Guy R. E. Van Lommen
Guy R. E. Van Lommen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 5624952Abstract: The present invention is concerned with vasoconstricive [(benzodioxan, benzofuran or benzopyran)alkylamino]alkyl substituted guanidines having the formula ##STR1## the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric forms thereof, wherein X is O, CH.sub.2 or a direct bond; R.sup.1 is hydrogen or C.sub.1-6 alkyl; R.sup.2 is hydrogen, C.sub.1-6 alkyl, C.sub.3-6 alkenyl or C.sub.3-6 alkynyl; R.sup.3 is hydrogen or C.sub.1-6 alkyl; or R.sup.2 and R.sup.3 may be taken together to form a bivalent radical of formula --(CH.sub.2).sub.m --, wherein m is 4 or 5; or R.sup.1 and R.sup.2 taken together may form a bivalent radical of formula --CH.dbd.CH-- or of formula --(CH.sub.2).sub.n --, wherein n is 2, 3 or 4; or R.sup.3 may represent a bond when R.sub.1 and R.sup.2 taken together form a bivalent radical of formula --CH.dbd.CH--CH.dbd., --CH.dbd.CH--N.dbd., or --CH.dbd.N--CH.dbd.; R.sup.4 is hydrogen or C.sub.1-6 alkyl; Alk.sup.1 is a bivalent C.sub.Type: GrantFiled: April 15, 1996Date of Patent: April 29, 1997Assignee: Janssen Pharmaceutica N.V.Inventors: Guy R. E. Van Lommen, Marcel F. L. De Bruyn, Walter J. J. Janssens
-
Patent number: 5607949Abstract: The present invention is concerned with vasoconstricive [(benzodioxan, benzofuran or benzopyran)alkylamino]alkyl substituted guanidines having the formula ##STR1## the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric forms thereof, wherein X is O, CH.sub.2 or a direct bond; R.sup.1 is hydrogen or C.sub.1-6 alkyl; R.sup.2 is hydrogen, C.sub.1-6 alkyl, C.sub.3-6 alkenyl or C.sub.3-6 alkynyl; R.sup.3 is hydrogen or C.sub.1-6 alkyl; or R.sup.2 and R.sup.3 may be taken together to form a bivalent radical of formula --(CH.sub.2).sub.m --, wherein m is 4 or 5; or R.sup.1 and R.sup.2 taken together may form a bivalent radical of formula --CH.dbd.CH-- or of formula --(CH.sub.2).sub.n --, wherein n is 2, 3 or 4; or R.sup.3 may represent a bond when R.sup.1 and R.sup.2 taken together form a bivalent radical of formula --CH.dbd.CH--CH.dbd., --CH.dbd.CH--N.dbd., or --CH.dbd.N--CH.dbd.; R.sup.4 is hydrogen or C.sub.1-6 alkyl; Alk.sup.1 is a bivalent C.sub.Type: GrantFiled: April 15, 1996Date of Patent: March 4, 1997Assignee: Janssen Pharmaceutica N.V.Inventors: Guy R. E. Van Lommen, Marcel F. L. De Bruyn, Walter J. J. Janssens
-
Patent number: 5541180Abstract: The present invention is concerned with vasoconstricive [(benzodioxan, benzofuran or benzopyran)alkylamino]alkyl substituted guanidines having the formula ##STR1## the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric forms thereof, wherein X is O, CH.sub.2 or a direct bond; R.sup.1 is hydrogen or C.sub.1-6 alkyl; R.sup.2 is hydrogen, C.sub.1-6 alkyl, C.sub.3-6 alkenyl or C.sub.3-6 alkynyl; R.sup.3 is hydrogen or C.sub.1-6 alkyl; or R.sup.2 and R.sup.3 may be taken together to form a bivalent radical of formula --(CH.sub.2).sub.m --, wherein m is 4 or 5; or R.sup.1 and R.sup.2 taken together may form a bivalent radical of formula --CH.dbd.CH-- or of formula --(CH.sub.2).sub.n --, wherein n is 2, 3 or 4; or R.sup.3 may represent a bond when R.sup.1 and R.sup.2 taken together form a bivalent radical of formula --CH.dbd.CH--CH.dbd., --CH.dbd.CH--N.dbd., or --CH.dbd.N--CH.dbd.; R.sup.4 is hydrogen or C.sub.1-6 alkyl;Alk.sup.1 is a bivalent C.sub.Type: GrantFiled: July 29, 1994Date of Patent: July 30, 1996Assignee: Janssen Pharmaceutica N.V.Inventors: Guy R. E. Van Lommen, Marcel F. L. De Bruyn, Walter J. J. Janssens
-
Patent number: 5369084Abstract: Isonicotinic acid derivatives and related furo-, thieno- and pyrrolo[3,4-c]pyridin-1(3H)-one, -thione and -imine compounds having the formula ##STR1## wherein R is ##STR2## Q is O, S or NR.sup.7 ; Y is O, S or NR.sup.8 ; L is COOR.sup.9, CONR.sup.10 R.sup.11, C(.dbd.S)NR.sup.10 R.sup.11, CN, or a radical of formula ##STR3## the acceptable addition salts, the stereochemically isomeric forms and the N-oxides thereof, having herbicidal properties, compositions containing the same and methods for controlling weeds.Type: GrantFiled: May 6, 1993Date of Patent: November 29, 1994Assignee: Janssen Pharmaceutical N.V.Inventors: Hans-Rudolf Waespe, Guy R. E. Van Lommen, Victor K. Sipido
-
Patent number: 5246915Abstract: A method for controlling weeds preferably in the crops of useful plants by using a 5-imidazolecarboxylic acid derivative; herbicidal compositions containing the same; novel 5-imidazolecarboxylic acid derivatives.Type: GrantFiled: February 26, 1992Date of Patent: September 21, 1993Assignee: Janssen Pharmaceutica N.V.Inventors: William R. Lutz, Guy R. E. Van Lommen, Jozef F. E. Van Gestel
-
Patent number: 4994103Abstract: Novel herbicidal 1,5-substituted 1H-imidazole derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants. Further the invention also relates to a process for making these novel compounds.Type: GrantFiled: October 12, 1989Date of Patent: February 19, 1991Assignees: Janssen Pharmaceutica N.V., Ciba-GeigyInventors: Marcel F. L. De Bruyn, Guy R. E. Van Lommen, William R. Lutz
-
Patent number: 4927449Abstract: Novel herbicidal tricyclic 1H-imidazole-5-carboxylic acid derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants.Type: GrantFiled: December 27, 1988Date of Patent: May 22, 1990Assignee: Janssen Pharmaceutica N.V.Inventors: William R. Lutz, Wim G. Verschueren, Hanspeter Fischer, Guy R. E. Van Lommen
-
Patent number: 4878940Abstract: Novel herbicidal 1,5-substituted 1H-imidazole derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants. Further the invention also relates to a process for making these novel compounds.Type: GrantFiled: March 25, 1988Date of Patent: November 7, 1989Assignee: Janssen Pharmaceutica N.V.Inventors: Marcel F. L. De Bruyn, Guy R. E. Van Lommen, William R. Lutz
-
Patent number: 4832732Abstract: Novel herbicidal 1-methyl-1H-imidazole -5-carboxylic acid derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants. Further the invention also relates to a process for making these novel compounds.Type: GrantFiled: December 17, 1987Date of Patent: May 23, 1989Assignee: Janssen Pharmaceutica N.V.Inventors: William R. Lutz, Guy R. E. Van Lommen, Victor Sipido, Wim G. Verschueren
-
Patent number: 4830664Abstract: Novel herbicidal tricyclic 1H-imidazole-5-carboxylic acid derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants.Type: GrantFiled: December 17, 1987Date of Patent: May 16, 1989Assignee: Janssen Pharmaceutica N.V.Inventors: William R. Lutz, Wim G. Verschueren, Hanspeter Fischer, Guy R. E. Van Lommen
-
Patent number: 4824472Abstract: Novel herbicidal 1-cyclyl or polycyclyl substituted 1H-imidazole-5-carboxylic acid derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants. Processes for making these novel compounds.Type: GrantFiled: December 23, 1987Date of Patent: April 25, 1989Assignee: Janssen Pharmaceutica N.V.Inventors: Guy R. E. Van Lommen, Victor Sipido, Wim G. Verschueren, William R. Lutz
-
Patent number: 4813998Abstract: Novel herbicidal 1-heterocyclyl-1H-imidazole-5-carboxylic acid derivatives, compositions containing these compounds as active ingredients, and a method for controlling weeds, preferably selectively in crops of useful plants. Further the invention also relates to a process for making these novel compounds.Type: GrantFiled: August 24, 1987Date of Patent: March 21, 1989Assignee: Janssen Pharmaceutica N.V.Inventors: Guy R. E. Van Lommen, William R. Lutz, Jozef F. E. Van Gestel
-
Patent number: 4770689Abstract: A method for controlling weeds preferably in the crops of useful plants by using a 1-methyl-1H-imidazole-5-carboxylic acid derivative; herbicidal compositions containing the same; 1-methyl-1H-imidazole-5-carboxylic acid derivatives.Type: GrantFiled: December 19, 1986Date of Patent: September 13, 1988Assignee: Janssen Pharmaceutica N.V.Inventors: Jozef F. E. Van Gestel, William R. Lutz, Guy R. E. Van Lommen, Hanspeter Fischer, Marc F. J. Schroven, Rudolph C. Thummel
-
Patent number: 4654362Abstract: Derivatives of 2,2'-iminobisethanol having useful properties in the treatment and/or the prevention of disorders of the coronary-vascular system.Type: GrantFiled: October 12, 1984Date of Patent: March 31, 1987Assignee: Janssen Pharmaceutica, N.V.Inventors: Guy R. E. Van Lommen, Marcel F. L. De Bruyn, Marc F. J. Schroven