Patents by Inventor Guy Rouleau

Guy Rouleau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10969933
    Abstract: A device may receive data associated with executing a model. The data may be associated with a solver used during execution of the model. The device may determine a presentation order of a plurality of model items based on the data associated with executing the model. The solver may be used to determine values associated with the plurality of model items. The presentation order of the plurality of model items may be determined based on a plurality of factors. The plurality of factors may be associated with the values. The device may generate a graphical interface that indicates the presentation order of the plurality of model items. The device may provide the graphical interface. The graphical interface may provide, for display, a list of the plurality of model items. The list may be provided in association with the presentation order.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: April 6, 2021
    Assignee: The MathWorks, Inc.
    Inventors: Guy Rouleau, Zhuohua Shen, Fu Zhang
  • Publication number: 20160215347
    Abstract: A novel gene (EPM2A) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EPM2A have been found that co-segregate with Lafora's disease.
    Type: Application
    Filed: April 7, 2016
    Publication date: July 28, 2016
    Applicants: The Hospital for Sick Children, McGill University, U.S. Government Department of Veterans Affairs, The Regents of the University of California
    Inventors: Stephen W. Scherer, Berge A. Minassian, Antonio Delgado-Escueta, Guy Rouleau
  • Patent number: 9334539
    Abstract: A novel gene (EPM2A) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EPM2A have been found that co-segregate with Lafora's disease.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: May 10, 2016
    Assignees: The Hospital for Sick Children, McGill University, The Regents of the University of California, U.S. Department of Veterans Affairs
    Inventors: Stephen W. Scherer, Berge A. Minassian, Antonio Delgado-Escueta, Guy Rouleau
  • Publication number: 20140057971
    Abstract: A novel gene (EPM2A) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EPM2A have been found that co-segregate with Lafora's disease.
    Type: Application
    Filed: June 24, 2013
    Publication date: February 27, 2014
    Applicants: The Hospital for Sick Children, The Regents of the University of California, U.S. Government Department of Veterans Affairs, McGill University
    Inventors: Stephen W. SCHERER, Berge A. Minassian, Antonio Delgado-Escueta, Guy Rouleau
  • Publication number: 20110229891
    Abstract: The invention identifies Syngap1 dysfunctions as causative of mental retardation. Described are methods of detecting mental retardation and methods of detecting non-syndromic mental retardation (NSMR) in a human subject. Particular methods comprise sequencing a human subject's genomic DNA for comparison with a control sequence from an unaffected individual. Also described are probes, kits, antibodies and isolated mutated Syngap1 proteins.
    Type: Application
    Filed: November 9, 2009
    Publication date: September 22, 2011
    Applicants: Centre Hospitalier Universitaire Saint-Justine, Universite De Montreal, Centre Hospitalier De L'Universite De Montreal
    Inventors: Jacques Michaud, Fadi Hamdan, Guy Rouleau, Julie Gauthier
  • Publication number: 20050069922
    Abstract: The present invention relates to a human PAB II gene containing transcribed polymorphic GCG repeat, which comprises a sequence as set forth in SEQ ID NO:3, which includes introns and flanking genomic sequence. The allelic variants of GCG repeat of the human PAB II gene are associated with a disease related with protein accumulation in nucleus, such as polyalanine accumulation, a disease related with swallowing difficulties, such as oculopharyngeal muscular dystrophy. The present invention also relates to a method for the diagnosis of a disease with protein accumulation in nucleus, which comprises the steps of: a) obtaining a nucleic acid sample of said patient; and b) determining allelic variants of GCG repeat of the gene of claim 1, and wherein long allelic variants are indicative of a disease related with protein accumulation in nucleus.
    Type: Application
    Filed: July 12, 2004
    Publication date: March 31, 2005
    Applicant: McGill University
    Inventors: Guy Rouleau, Bernard Brais