Patents by Inventor Guy Simpson

Guy Simpson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11969286
    Abstract: A system for visualization and quantification of ultrasound imaging data according to embodiments of the present disclosure may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to estimate axial and lateral velocity components of the fluid flowing within the bodily structure, determine a plurality of flow directions within the image based on the axial and lateral velocity components, differentially encode the flow directions based on flow direction angle to generate a flow direction map, and cause the display unit to concurrently display the image including the bodily structure overlaid with the flow direction map.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: April 30, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Hua Xie, Shiying Wang, Sheng-Wen Huang, Francois Guy Gerard Marie Vignon, Keith William Johnson, Liang Zhang, David Hope Simpson
  • Patent number: 11950962
    Abstract: Ultrasound imaging systems and methods for generated clutter-reduced images are provided. For example, an ultrasound imaging system can include an array of acoustic elements in communication with a processor. The processor is configured to activate the array to perform a scan sequence to obtain a plurality of signals, identify off-axis signals from the plurality of signals by comparing the right subaperture and the left subaperture, and create a clutter-reduced image based on the comparison. Because off-axis signals are more likely to create image clutter, reducing the influence of off-axis signals on the image can therefore improve the quality of the image. Accordingly, embodiments of the present disclosure provide systems, methods, and devices for generating ultrasound images that have reduced or minimized clutter, even for images obtained using arrays that do not satisfy the Nyquist criterion.
    Type: Grant
    Filed: November 1, 2022
    Date of Patent: April 9, 2024
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Andrew Hancock, Yiqun Yang, David Hope Simpson, Francois Guy Gerard Marie Vignon, Jun Seob Shin
  • Publication number: 20190134120
    Abstract: The present invention relates to methods of treating bladder cancer with human enterovirus C (HEC) in combination with chemotherapy or radiation therapy. The present invention also relates to methods for increasing susceptibility of a cancer cell to infection by HEC.
    Type: Application
    Filed: August 3, 2018
    Publication date: May 9, 2019
    Inventors: DARREN SHAFREN, Gough Au, Hardev Pandha, Guy Simpson
  • Publication number: 20160136211
    Abstract: The present invention relates to methods of treating bladder cancer with human enterovirus C (HEC) in combination with chemotherapy or radiation therapy. The present invention also relates to methods for increasing susceptibility of a cancer cell to infection by HEC.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 19, 2016
    Inventors: Darren Raymond Shafren, Gough AU, Hardev Pandha, Guy Simpson
  • Publication number: 20060188480
    Abstract: The present invention provides a herpes virus which lacks a functional ICP34.5 encoding gene and which comprises two or more of—(i) a gene encoding a prodrug converting enzyme; (ii) a gene encoding a protein capable of causing cell to cell fusion; and (iii) a gene encoding an immunomodulatory protein.
    Type: Application
    Filed: January 25, 2006
    Publication date: August 24, 2006
    Applicant: BIOVEX LIMITED
    Inventors: Robert Coffin, Guy Simpson
  • Patent number: 6105053
    Abstract: An operating system for a non-uniform memory access (NUMA) multiprocessor system that utilizes a software abstraction of the NUMA system hardware representing a hierarchical tree structure to maintain the most efficient level of affinity and to maintain balanced processor and memory loads. The hierarchical tree structure includes leaf nodes representing the job processors, a root node representing at least one system resource shared by all the job processors, and a plurality of intermediate level nodes representing resources shared by different combinations of the job processors. The operating system includes a medium term scheduler for monitoring the progress of active thread groups distributed throughout the system and for assisting languishing thread groups, and a plurality of dispatchers each associated with one of the job processors for monitoring the status of the associated job processor and for obtaining thread groups for the associated job processor to execute.
    Type: Grant
    Filed: June 23, 1995
    Date of Patent: August 15, 2000
    Assignee: EMC Corporation
    Inventors: Jeffrey S. Kimmel, Robert A. Alfieri, Miles A. de Forest, William K. McGrath, Michael J. McLeod, Mark A. O'Connell, Guy A. Simpson