Abstract: This invention relates to a device for releasably clamping a cutting insert on a tool-holder. A screw having a threaded shank adapted to be screwed in a tapped hold in the tool-holder passes through an eccentric cylindrical hole in the insert. The head of the screw includes, from the shank, a truncated bearing surface, a cylindrical bearing surface and a shoulder. The screw head cooperates with the edge and the wall of the eccentric hole in the insert to press the sides of the latter against the lateral stop faces of the tool-holder and the base of said insert against the bearing face of said tool-holder.