Patents by Inventor Gwénaëlle RET

Gwénaëlle RET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20220409595
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 29, 2022
    Inventors: John P. LEONARD, Jean-François DELEUZE, Jean-Michel ITIER, Cécile ORSINI, Gwénaëlle RET-LECUELLE, Sandra VIALE
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20190046509
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy.
    Type: Application
    Filed: April 5, 2018
    Publication date: February 14, 2019
    Inventors: JOHN P. LEONARD, JEAN-FRANÇOIS DELEUZE, JEAN-MICHEL ITIER, CÉCILE ORSINI, GWÉNAËLLE RET-LECUELLE, SANDRA VIALE
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20160361301
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy.
    Type: Application
    Filed: December 9, 2014
    Publication date: December 15, 2016
    Inventors: JOHN P. LEONARD, JEAN-FRANÇOIS DELEUZE, JEAN-MICHEL ITIER, CÉCILE ORSINI, GWÉNAËLLE RET-LECUELLE, SANDRA VIALE
  • Method for identifying an antagonist of guanine nucleotide releasing factor 1
    Patent number: 8852878
    Abstract: The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: October 7, 2014
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Michel Itier, Marie-Christine Multon, Gwénaëlle Ret, Jean-Marie Stutzmann, Florence Wahl
  • USE OF GRF1 PROTEIN FOR SCREENING MOLECULES
    Publication number: 20120009604
    Abstract: The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.
    Type: Application
    Filed: August 3, 2011
    Publication date: January 12, 2012
    Applicant: AVENTIS PHARMA SA
    Inventors: Jean-Michel ITIER, Marie-Christine MULTON, Gwénaëlle RET, Jean-Marie STUTZMANN, Florence WAHL
  • Use of grf1 protein for screening molecules
    Publication number: 20050100972
    Abstract: The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.
    Type: Application
    Filed: August 7, 2001
    Publication date: May 12, 2005
    Inventors: Jean-Michel Itier, Marie-Christine Multon, Gwenaelle Ret, Jean-Marie Stutzmann, Florence Wahl