Abstract: A nasal powder delivery device having a container containing a dose of powder, a nasal delivery head, and an air discharge system generating a flow of compressed air for delivering a dose of powder into the nostril. An air chamber is arranged in a skirt, and a piston sealingly slides in the air chamber to compress the air. The piston is connected to an actuating member, in which, before actuation, at least one breakable bridge is provided between the skirt and the actuating member, wherein each breakable bridge is formed on the skirt and cooperates with a radial projection formed on the actuating member. Each radial projection has an axial extension greater than that of the respective breakable bridge and forms an inclined axial ramp on either side.