Patents by Inventor Gyan Mishra

Gyan Mishra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of selected amino acid-zinc complexes as anti-malarials
    Publication number: 20050090480
    Abstract: The invention provides the use of zinc complexes of selected amino acids from D or L isomers of proline, lysine, histidine, glycine, arginine and tryptophan or their various hydroxyl, amino, alkyl and carboxyl derivatives and zinc chloride, zinc acetate or other pharmacologically acceptable salts of zinc. The use of the compound comprises administering an effective amount of said compounds for inhibition of growth: of the malarial parasite, Plasmodium falciparum. The compound is lethal to the parasite in RBC cultures but have no effect on the RBCs. The compound has also displayed activity against, the chloroquine-resistant strain-W2Mef. The dose response curves for both 3D7 and W2Mef strains are identical which strongly suggested that the compound is equally effective against field isolates of chloroquine-resistant, P. falciparum. The compound acts on W2Mef strain through killing the target.
    Type: Application
    Filed: July 19, 2004
    Publication date: April 28, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Pawan Malhotra, Palakodeti Venkata Dasaradhi, Asif Mohammed, Manzar Hossain, Sunil Mukherji, Manivel Venkatasamy, Kanury Rao, Gyan Mishra, Parameswaran Subrayan, Anil Chatterji
  • Method and composition for treating osteoporosis
    Publication number: 20050085537
    Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.
    Type: Application
    Filed: December 30, 2003
    Publication date: April 21, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Kanury Rao, Mohan Wani, Venkatasamy Manivel, Parameswaran Subrayan, Vinod Singh, Ramasamy Anand, Ehrlich Desa, Gyan Mishra, Anil Chatterji
  • Monoclonal antibody against costimulatory molecule M150 and a process for preparation thereof
    Publication number: 20050037434
    Abstract: The present invention relates to a monoclonal antibody directed against the 150 kDa protein M150 on activated macrophages.
    Type: Application
    Filed: August 13, 2004
    Publication date: February 17, 2005
    Applicant: National Centre for Cell Science
    Inventors: Durbaka Prasad, Pradeep Parab, Gyan Mishra