Patents by Inventor Gyochang Keum

Gyochang Keum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same
    Patent number: 6759419
    Abstract: The present invention relates to substituted pyrrolidinone compounds of formula 1, wherein n is 0 or 1; Aza is a heterocycle optionally substituted with C1-4 alkyl, or C1-4 alkyl substituted with a heterocycle, which represents a saturated or unsaturated five- or six-membered ring having nitrogen(s) as a heteroatom, which are muscarinic acetylcholine receptor agonists and useful as nootropics and therapeutic agents for cerebral neural diseases such as Alzheimer's disease; and pharmaceutically acceptable salts thereof; processes for the preparation thereof; and pharmaceutical compositions comprising these compounds or salts.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: July 6, 2004
    Assignee: Korea Institute of Science and Technology
    Inventors: Youseung Kim, Soon Bang Kang, Gyochang Keum, Min Seok Jang, Jae Yang Kong, Dae Young Jeong, Taeg-Su Jang
  • Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors
    Patent number: 6716857
    Abstract: The present invention relates to novel tetrahydropyridine derivatives of formula 1 having an appropriately substituted pyrrolidinone and oxime, wherein m is 0 or 1, n is 1 or 2, R1 is hydrogen, C1-4alkyl, C2-4 alkynyl or aryl, R3 is C1-4 alkyl, which show high efficacy, low cholinergic adverse effects and high affinity for muscarinic acetylcholine receptor; and pharmaceutically acceptable salts thereof; processes for the preparation thereof; and pharmaceutical compositions comprising these compounds or salts.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: April 6, 2004
    Assignee: Korea Institute of Science and Technology
    Inventors: Youseung Kim, Soon Bang Kang, Gyochang Keum, Min Seok Jang, Jae Yang Kong, Dae Young Jeong
  • Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors
    Publication number: 20030119880
    Abstract: The present invention relates to novel tetrahydropyridine derivatives of formula 1 having an appropriately substituted pyrrolidinone and oxime, 1
    Type: Application
    Filed: October 18, 2002
    Publication date: June 26, 2003
    Inventors: Youseung Kim, Soon Bang Kang, Gyochang Keum, Min Seok Jang, Jae Yang Kong, Dae Young Jeong
  • Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same
    Publication number: 20030114491
    Abstract: The present invention relates to substituted pyrrolidinone compounds of formula 1, 1
    Type: Application
    Filed: October 18, 2002
    Publication date: June 19, 2003
    Inventors: Youseung Kim, Soon Bang Kang, Gyochang Keum, Min Seok Jang, Jae Yang Kong, Dae Young Jeong