Patents by Inventor Gyongyi Szakalas-Gratzl

Gyongyi Szakalas-Gratzl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vasopressin liquid formulations
    Patent number: 11684573
    Abstract: A liquid pharmaceutical composition for intravenous administration that includes vasopressin or a pharmaceutically acceptable salt thereof. The formulation further includes a lactate buffer or lactic acid, optionally in combination with a pH adjuster. The pharmaceutical composition can have a pH of from about 3.0 to about 4.1 and demonstrates improved stability for long term storage, particularly at room temperature.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: June 27, 2023
    Assignee: HIKMA PHARMACEUTICALS USA INC.
    Inventors: Gyongyi Szakalas-Gratzl, Ping Ma, James Murtagh
  • Nonthrombogenic implant surfaces
    Patent number: 5993890
    Abstract: Triblock polymers comprised of polysaccharide, such as heparin or dextran, and a hydrocarbon chain, have been prepared. The triblock polymer adsorbs strongly on the surface of hydrophobic polymer substrates such as polyethylene, through hydrophobic interaction between the polymer and the hydrophobic hydrocarbon chain of the triblock polymer. The surface adsorbed with triblock polymer is resistant to protein deposition, which renders the surface nonthrombogenic.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 30, 1999
    Assignee: Case Western Reserve University
    Inventors: Roger E. Marchant, Shengmei Yuan, Gyongyi Szakalas-Gratzl
  • Nonthrombogenic implant surfaces
    Patent number: 5741852
    Abstract: Triblock polymers comprised of polysaccharide, such as heparin or dextran, and a hydrocarbon chain, have been prepared. The triblock polymer adsorbs strongly on the surface of hydrophobic polymer substrates such as polyethylene, through hydrophobic interaction between the polymer and the hydrophobic hydrocarbon chain of the triblock polymer. The surface adsorbed with triblock polymer is resistant to protein deposition, which renders the surface nonthrombogenic.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: April 21, 1998
    Assignee: Case Western Reserve University
    Inventors: Roger E. Marchant, Shengmei Yuan, Gyongyi Szakalas-Gratzl