Abstract: An image processing apparatus comprises a normalisation module operatively connected across a bus to a memory storing an image in which a region of interest (ROI) has been identified within the image. The ROI is bound by a rectangle having a non-orthogonal orientation within the image. In one embodiment, the normalisation module is arranged to divide the ROI into one or more slices, each slice comprising a plurality of adjacent rectangular tiles. For each slice, the apparatus successively reads ROI information for each tile from the memory including: reading a portion of the image extending across at least a width of the slice line-by-line along an extent of a slice. For each tile, the apparatus downsamples the ROI information to a buffer to within a scale SD<2 of a required scale for a normalised version of the ROI.

Abstract: An image processing apparatus comprises a normalisation module operatively connected across a bus to a memory storing an image in which a region of interest (ROI) has been identified within the image. The ROI is bound by a rectangle having a non-orthogonal orientation within the image. In one embodiment, the normalisation module is arranged to divide the ROI into one or more slices, each slice comprising a plurality of adjacent rectangular tiles. For each slice, the apparatus successively reads ROI information for each tile from the memory including: reading a portion of the image extending across at least a width of the slice line-by-line along an extent of a slice. For each tile, the apparatus downsamples the ROI information to a buffer to within a scale SD<2 of a required scale for a normalised version of the ROI.

Abstract: An image processing apparatus comprises a normalisation module operatively connected across a bus to a memory storing an image in which a region of interest (ROI) has been identified within the image. The ROI is bound by a rectangle having a non-orthogonal orientation within the image. In one embodiment, the normalisation module is arranged to divide the ROI into one or more slices, each slice comprising a plurality of adjacent rectangular tiles. For each slice, the apparatus successively reads ROI information for each tile from the memory including: reading a portion of the image extending across at least a width of the slice line-by-line along an extent of a slice. For each tile, the apparatus downsamples the ROI information to a buffer to within a scale SD<2 of a required scale for a normalised version of the ROI.

Abstract: An image processing apparatus comprises a normalisation module operatively connected across a bus to a memory storing an image in which a region of interest (ROI) has been identified within the image. The ROI is bound by a rectangle having a non-orthogonal orientation within the image. In one embodiment, the normalisation module is arranged to divide the ROI into one or more slices, each slice comprising a plurality of adjacent rectangular tiles. For each slice, the apparatus successively reads ROI information for each tile from the memory including: reading a portion of the image extending across at least a width of the slice line-by-line along an extent of a slice. For each tile, the apparatus downsamples the ROI information to a buffer to within a scale SD<2 of a required scale for a normalised version of the ROI.

Abstract: Diuretic and saluretic tetrahydro-isoquinoline derivatives of the Formula (I) ##STR1## wherein R stands for hydrogen or chlorine,R.sup.1 and R.sup.2 are hydrogen, methoxy or ethoxy, andR.sup.3 and R.sup.4 are hydrogen or methyl,and a process for the preparation thereof as well as pharmaceutical compositions containing as active ingredients isoquinoline derivatives of the Formula (I). The compounds of Formula I are prepared by reacting a 2-amino-tetrahydro-isoquinoline derivative of the Formula (II) ##STR2## with a carboxylic acid derivative of the Formula (III) ##STR3## wherein x stands for chlorine, --OH, --OCH.sub.2 CN, --OCH.sub.3, --OC.sub.2 H.sub.5, --OCOOCH.sub.3 or --OCOOC.sub.2 H.sub.5R.sup.5 and R.sup.6 stand for hydrogen or together from CHN(CH.sub.3).sub.2 and in case of the Formula (Ia) ##STR4## splitting off the protective group in alkaline medium.

Abstract: The present invention relates to novel compounds of the general formula ##STR1## wherein R is hydrogen atom or a trifluoromethyl, carboxy, C.sub.2-5 alkoxycarbonyl, cyano, benzoyl, sulfamoyl or C.sub.1-4 alkylsulfonyl group;R.sup.1 is hydrogen atom or a linear or branched chain C.sub.1-4 alkyl, C.sub.1-4 alkylthio, C.sub.1-4 alkylsulfonyl, benzylthio, benzylsulfonyl, phenyl, hydroxy or mercapto group; andR.sup.2 is hydrogen or chlorine atom,as well as their pharmaceutically acceptable salts.The compounds according to the invention possess diuretic and saluretic activity with an advantageous Na/K ratio.