Patents by Inventor Gyu-Jin RHO

Gyu-Jin RHO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220339196
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating obesity or non-alcoholic fatty liver, containing dental tissue-derived mesenchymal stem cells cryopreserved by vitrification. The pharmaceutical composition for preventing or treating obesity or non-alcoholic fatty liver, of the present invention, reduces body weight, lowers serum adipokine concentration, allows the liver to recover in view of histological findings, and improves lipid metabolic enzymes in the liver, thereby exhibiting remarkable prevention and treatment effects on obesity or non-alcoholic fatty liver. In addition, dental tissue-derived mesenchymal stem cells, which are the active ingredients of the present invention, are mesodermal stem cells having verified safety and may be obtained with the least invasiveness, and thus are expected to be effectively used as a cell therapeutic agent for obesity or non-alcoholic fatty liver.
    Type: Application
    Filed: September 7, 2020
    Publication date: October 27, 2022
    Inventors: Gyu Jin Rho, Kyung Min Kim, Si Jung Jang, Sung Lim Lee, Bong Wook Park, Hyeon Jeong Lee
  • Publication number: 20220226385
    Abstract: The present invention relates to a pharmaceutical composition including vitrified periodontal tissue-derived mesenchymal stem cells for prevention or treatment of male infertility. The pharmaceutical composition for prevention or treatment of male infertility according to the present invention recovers sex hormone levels in seminiferous tubules of atrophic testes and blood to normal levels through improvement in the activity of lipid metabolism enzymes in the liver, thereby exhibiting remarkable prophylactic and therapeutic effects on male infertility. In addition, the periodontal tissue-derived mesenchymal stem cells which are an active ingredient in the present invention can be obtained in the most non-invasive manner and as such, are expected to be advantageously used as a cell therapy product for male infertility.
    Type: Application
    Filed: May 8, 2020
    Publication date: July 21, 2022
    Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY, STEMCENTRIC CO., LTD.
    Inventors: Gyu Jin Rho, Kyung Min Kim, Si Jung Jang, Sung Lim Lee, Bong Wook Park
  • Patent number: 11007240
    Abstract: Disclosed are uses of ginseng saponin, which contains at least 90% of a compound K, Rd, F2, and Rg3 as a main ingredient and has effects in extending the lifespan of the cell, promoting the cell differentiation, increasing the number of red blood cells, and reducing the triglycerides by extracting, heat-treating, and enzyme-converting the ginseng saponin to prepare active saponins Rd, F2, and Rg3 including a compound K.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: May 18, 2021
    Assignee: KOREAN DRUG CO., LTD.
    Inventors: Jae Seon Kang, Bo Suel Kim, Heyong-Soo Kim, Gyu-Jin Rho, Sin-Ja Bae, Seo Hyun Lee, Jong Jin Park, Choel-Min Kim
  • Patent number: 10765715
    Abstract: Disclosed are uses of ginseng saponin, which contains at least 90% of a compound K, Rd, F2, and Rg3 as a main ingredient and has effects in extending the lifespan of the cell, promoting the cell differentiation, increasing the number of red blood cells, and reducing the triglycerides by extracting, heat-treating, and enzyme-converting the ginseng saponin to prepare active saponins Rd, F2, and Rg3 including a compound K.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: September 8, 2020
    Assignee: KOREAN DRUG CO., LTD.
    Inventors: Jae Seon Kang, Bo Suel Kim, Heyong-Soo Kim, Gyu-Jin Rho, Sin-Ja Bae, Seo Hyun Lee, Jong Jin Park, Choel-Min Kim
  • Publication number: 20200246407
    Abstract: Disclosed are uses of ginseng saponin, which contains at least 90% of a compound K, Rd, F2, and Rg3 as a main ingredient and has effects in extending the lifespan of the cell, promoting the cell differentiation, increasing the number of red blood cells, and reducing the triglycerides by extracting, heat-treating, and enzyme-converting the ginseng saponin to prepare active saponins Rd, F2, and Rg3 including a compound K.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 6, 2020
    Applicant: KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION
    Inventors: Jae Seon KANG, Bo Suel KIM, Heyong-Soo KIM, Gyu-Jin RHO, Sin-Ja BAE, Seo Hyun LEE, Jong Jin PARK, Choel-Min KIM
  • Publication number: 20180369309
    Abstract: Disclosed are uses of ginseng saponin, which contains at least 90% of a compound K, Rd, F2, and Rg3 as a main ingredient and has effects in extending the lifespan of the cell, promoting the cell differentiation, increasing the number of red blood cells, and reducing the triglycerides by extracting, heat-treating, and enzyme-converting the ginseng saponin to prepare active saponins Rd, F2, and Rg3 including a compound K.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 27, 2018
    Applicant: KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION
    Inventors: Jae Seon KANG, Bo Suel KIM, Heyong-Soo KIM, Gyu-Jin RHO, Sin-Ja BAE, Seo Hyun LEE, Jong Jin PARK, Choel-Min KIM