Patents by Inventor H. Alex Brown

H. Alex Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS COMPRISING AKT INHIBITORS AND/OR PHOSPHOLIPASE D INHIBITORS
    Publication number: 20170319611
    Abstract: Disclosed are methods of treating viral infections or disorders of uncontrolled proliferation comprising, in one aspect, administering compounds that are phospholipase D inhibitors and/or Akt therapeutic agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: April 28, 2017
    Publication date: November 9, 2017
    Inventors: H. Alex Brown, Craig W. Lindsley
  • Methods and Compositions for Treating HIV Infection
    Publication number: 20160296506
    Abstract: Disclosed are methods of treating HIV infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 22, 2016
    Publication date: October 13, 2016
    Inventors: H. Alex Brown, Craig W. Lindsley
  • Isoform selective phospholipase D inhibitors
    Patent number: 9127005
    Abstract: Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: September 8, 2015
    Assignee: Vanderbilt University
    Inventors: H. Alex Brown, Craig W. Lindsley, Alex G. Waterson, Sarah A. Scott
  • ANTIVIRAL THERAPIES WITH PHOSPHOLIPASE D INHIBITORS
    Publication number: 20150025041
    Abstract: Disclosed are methods of treating viral infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to antiviral therapies. For example, compounds having Phospholipase D activity (e.g., isoform selective Phospholipase D inhibitors) can be useful in antiviral therapies (e.g., influenza treatments).
    Type: Application
    Filed: September 30, 2012
    Publication date: January 22, 2015
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Craig W. Lindsley, H. Alex Brown
  • METHODS AND COMPOSITIONS COMPRISING AKT INHIBITORS AND/OR PHOSPHOLIPASE D INHIBITORS
    Publication number: 20140378524
    Abstract: Disclosed are methods of treating viral infections or disorders of uncontrolled proliferation comprising, in one aspect, administering compounds that are phospholipase D inhibitors and/or Akt therapeutic agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 11, 2013
    Publication date: December 25, 2014
    Inventors: H. Alex Brown, Craig W. Lindsley
  • METHODS AND COMPOSITIONS OF TREATING HIV INFECTION
    Publication number: 20140163055
    Abstract: Disclosed are methods of treating HIV infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 12, 2014
    Inventors: H. Alex Brown, Craig W. Lindsley
  • ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS
    Publication number: 20120214832
    Abstract: Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: July 23, 2010
    Publication date: August 23, 2012
    Inventors: H. Alex Brown, Craig W. Lindsley, Alex G. Waterson, Sarah A. Scott