Patents by Inventor H. Andrew Strong

H. Andrew Strong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190029986
    Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
    Type: Application
    Filed: May 1, 2018
    Publication date: January 31, 2019
    Inventors: H. Andrew Strong, Suzanne Cadden
  • Patent number: 9987245
    Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: June 5, 2018
    Assignee: Novelion Therapeutics Inc.
    Inventors: H. Andrew Strong, Suzanne Cadden
  • Publication number: 20170087114
    Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
    Type: Application
    Filed: October 5, 2015
    Publication date: March 30, 2017
    Inventors: H. Andrew Strong, Suzanne Cadden
  • Patent number: 9226917
    Abstract: The use of a combination of photodynamic therapy and an anti-VEGF agent in the treatment of conditions characterized by unwanted choroidal neovasculature is described. These conditions include wet age-related macular degeneration Preferred anti-VEGF agents are antibodies such as bevacizumab or ranibizumab Photosensitizers may be selected from green porphyrins such as BPD-MA (verteporfin) and the photodynamic activation of the photo sensitizer may be accomplished using a reduced fluence rate. The use may further comprises an anti-inflammatory agent such as dexamethasone.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: January 5, 2016
    Assignee: Valeant Pharmaceuticals International, Inc.
    Inventors: H. Andrew Strong, Yong Hao
  • Patent number: 9173856
    Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: November 3, 2015
    Assignee: QLT INC.
    Inventors: H. Andrew Strong, Suzanne Cadden
  • Publication number: 20120310144
    Abstract: Photodynamic therapy of conditions of the eye, especially those conditions characterized by unwanted neovasculature, such as age-related macular degeneration, results in enhanced visual acuity for treated subjects.
    Type: Application
    Filed: August 13, 2012
    Publication date: December 6, 2012
    Inventors: H. Andrew STRONG, Julia Levy, Gustav Huber, Mario Fsadni
  • Patent number: 8239978
    Abstract: Photodynamic therapy of conditions of the eye, especially those conditions characterized by unwanted neovasculature, such as age-related macular degeneration, results in enhanced visual acuity for treated subjects.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: August 14, 2012
    Assignee: Novartis Opthalmics AG
    Inventors: H. Andrew Strong, Julia G. Levy, Gustav Huber, Mario Fsadni
  • Publication number: 20120041356
    Abstract: The use of a combination of photodynamic therapy and an anti-VEGF agent in the treatment of conditions characterized by unwanted choroidal neovasculature is described. These conditions include wet age-related macular degeneration Preferred anti-VEGF agents are antibodies such as bevacizumab or ranibizumab Photosensitizers may be selected from green porphyrins such as BPD-MA (verteporfin) and the photodynamic activation of the photo sensitizer may be accomplished using a reduced fluence rate. The use may further comprises an anti-inflammatory agent such as dexamethasone.
    Type: Application
    Filed: December 16, 2009
    Publication date: February 16, 2012
    Applicant: QLT INC.
    Inventors: H. Andrew Strong, Yong Hao
  • Publication number: 20110257266
    Abstract: Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
    Type: Application
    Filed: April 19, 2011
    Publication date: October 20, 2011
    Applicant: QLT, INC.
    Inventors: H. Andrew Strong, Suzanne Cadden
  • Patent number: 8034803
    Abstract: The invention relates to the selection and treatment of subjects afflicted with occult choroidal neovascular lesions, including subjects with age-related macular degeneration, by use of photo dynamic therapy (PDT).
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: October 11, 2011
    Assignees: QLT Inc., Novartis, A.G.
    Inventors: H. Andrew Strong, Mohammad Azab, Yong Hao, John Miller Koester, Troy Albert Reaves, Jr.
  • Patent number: 7753943
    Abstract: The invention relates to the use of reduced fluency rate PDT to treat neovasculature, particularly choroidal neovasculature (CNV). Reduced fluency rate PDT decreases the likelihood of molecular oxygen being the limiting factor in the photodynamic reaction so that the concentration of either photons (light intensity) or photosensitizer in the target tissue controls the photodynamic reaction.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: July 13, 2010
    Assignee: QLT Inc.
    Inventor: H. Andrew Strong
  • Patent number: 7060695
    Abstract: An improved method to treat conditions of the eye characterized by ocular neovascularization is provided in which patients are given and initial photodynamic therapy (PDT) treatment to destroy the neovasculature, and then are re-evaluated at least twice during the following 6 months, and retreated as necessary. Preferably, three retreatments are provided.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: June 13, 2006
    Assignees: QLT, Inc., Novartis AG
    Inventors: H. Andrew Strong, Mohammad Azab, Troy Albert Reaves, Jr.
  • Patent number: 7015240
    Abstract: The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: March 21, 2006
    Assignee: QLT, Inc.
    Inventors: Janice North, Peter Hnik, H. Andrew Strong
  • Patent number: 6800086
    Abstract: The invention relates to the use of reduced fluence rate PDT to treat neovasculature, particularly choroidal neovasculature (CNV). Reduced fluence rate PDT decreases the likelihood of molecular oxygen being the limiting factor in the photodynamic reaction so that the concentration of either photons (light intensity) or photosensitizer in the target tissue controls the photodynamic reaction.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: October 5, 2004
    Assignee: QLT Inc.
    Inventor: H. Andrew Strong
  • Publication number: 20040122491
    Abstract: The invention relates to the use of reduced fluence rate PDT to treat neovasculature, particularly choroidal neovasculature (CNV). Reduced fluence rate PDT decreases the likelihood of molecular oxygen being the limiting factor in the photodynamic reaction so that the concentration of either photons (light intensity) or photosensitizer in the target tissue controls the photodynamic reaction.
    Type: Application
    Filed: August 14, 2003
    Publication date: June 24, 2004
    Inventor: H. Andrew Strong
  • Publication number: 20040019032
    Abstract: The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
    Type: Application
    Filed: July 17, 2003
    Publication date: January 29, 2004
    Inventors: Janice North, Peter Hnik, H. Andrew Strong
  • Publication number: 20030149012
    Abstract: Photodynamic therapy of conditions of the eye, especially those conditions characterized by unwanted neovasculature, such as age-related macular degeneration, results in enhanced visual acuity for treated subjects.
    Type: Application
    Filed: March 7, 2003
    Publication date: August 7, 2003
    Inventors: H. Andrew Strong, Julia Levy, Gustav Huber, Mario Fsadni
  • Patent number: 6599891
    Abstract: The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: July 29, 2003
    Assignee: QLT Inc.
    Inventors: Janice North, Peter Hnik, H. Andrew Strong
  • Publication number: 20030099596
    Abstract: The invention relates to the use of photodynamic therapy (PDT) to treat macular edemas, including DME, CRVO and BRVO. It provides an alternative to photocoagulation and the disadvantages associated therewith.
    Type: Application
    Filed: July 19, 2002
    Publication date: May 29, 2003
    Inventors: Janice North, Peter Hnik, H. Andrew Strong
  • Publication number: 20030087889
    Abstract: The invention relates to the selection and treatment of subjects afflicted with occult choroidal neovascular lesions, including subjects with age-related macular degeneration, by use of photo dynamic therapy (PDT).
    Type: Application
    Filed: February 6, 2002
    Publication date: May 8, 2003
    Inventors: H. Andrew Strong, Mohammad Azab, Yong Hao, John Miller Koester, Troy Albert Reaves