Patents by Inventor H. Daniel Perez

H. Daniel Perez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity soluble interleukin-18 receptor
    Publication number: 20020052475
    Abstract: A soluble, heterodimeric interleukin 18 (IL-18) receptor molecule is described which comprises two subunits, one of which comprises an extracelluar domain, or a fragment thereof, of IL-18R, and the other of which comprises an extracelluar domain, or a fragment thereof, of AcPL. Preferably, the soluble, heterodimeric receptor binds to IL-18 with higher affinity than does either IL-18R or AcPL alone.
    Type: Application
    Filed: July 19, 2001
    Publication date: May 2, 2002
    Applicant: Schering AG
    Inventors: Stewart Leung, H. Daniel Perez, Neil Miyamoto
  • Bispecific monoclonal antibodies to IL-12 and IL-18
    Publication number: 20020025317
    Abstract: A bispecific monoclonal antibody is described which comprises two moieties, one of which comprises an antigen-binding region which is specific for either the IL-12R&bgr;1 or the IL-12R&bgr;2 subunit of an IL-12 receptor, and the other of which comprises an antigen-binding region which is specific for either the IL-18R or the AcPL subunit of an IL-18 receptor.
    Type: Application
    Filed: July 19, 2001
    Publication date: February 28, 2002
    Applicant: Schering AG
    Inventors: Stewart Leung, H. Daniel Perez, Neil Miyamoto
  • Pharmaceutical preparations for TNF inhibition
    Patent number: 6117895
    Abstract: Compounds of formula I ##STR1## are useful for treating TNF-mediated diseases.
    Type: Grant
    Filed: July 18, 1996
    Date of Patent: September 12, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Helmut Wachtel, Hermann Graf, Herbert Schneider, Daryl Faulds, H. Daniel Perez, Harald Dinter
  • Combined treatment of multiple sclerosis
    Patent number: 6060501
    Abstract: A pharmaceutically composition for treating MS comprising an effective amount of a combination of a PDE IV inhibitor and an anti-inflammatory and immunomodulatory drug in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: September 24, 1997
    Date of Patent: May 9, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Helmut Wachtel, Peter-Andreas Loschmann, Hermann Graf, H. Daniel Perez