Patents by Inventor H. Frederick Bowman

H. Frederick Bowman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10258274
    Abstract: A unitary multilumen cranial bolt for use in multimodal monitoring of a plurality of physiological parameters in brain tissue incorporates a plurality of lumens, each lumen directing a catheter borne sensor through a bore hole in the cranium and into brain tissue of a patient. The lumens are configured to cause the catheters to splay outward as they enter the cranial cavity and reach their intended depth of penetration. Each lumen is associated with a guide. The guides are adapted for use with introducers that enable fragile and/or flexible sensors to be introduced into brain tissue. Each catheter borne sensor can be positioned and repositioned within brain tissue independently of all other sensors.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: April 16, 2019
    Assignee: Thermal Technologies, Inc.
    Inventors: H Frederick Bowman, Sammy M Khalifa, Dean Honkonen
  • Patent number: 10052064
    Abstract: An edema monitor uses patient-specific measurements of tissue conductivity and tissue perfusion and an empirically developed perfusion coefficient of thermal conductivity to obtain tissue intravascular water and tissue extravacular water components of tissue total water. Edema is an excess of tissue extravacular water. A value for edema is obtained by deducting from the obtained value for tissue extravacular water a normal value for tissue extravacular water.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: August 21, 2018
    Assignee: Thermal Technologies, Inc.
    Inventor: H. Frederick Bowman
  • Publication number: 20180092590
    Abstract: A unitary multilumen cranial bolt for use in multimodal monitoring of a plurality of physiological parameters in brain tissue incorporates a plurality of lumens, each lumen directing a catheter borne sensor through a bore hole in the cranium and into brain tissue of a patient. The lumens are configured to cause the catheters to splay outward as they enter the cranial cavity and reach their intended depth of penetration. Each lumen is associated with a guide. The guides are adapted for use with introducers that enable fragile and/or flexible sensors to be introduced into brain tissue. Each catheter borne sensor can be positioned and repositioned within brain tissue independently of all other sensors.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 5, 2018
    Applicant: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Sammy M. Khalifa, Dean Honkonen
  • Patent number: 9924878
    Abstract: Methods and apparatus for determining blood flow in tissue are disclosed. The methods and apparatus are used to establish a baseline for both thermal properties of the tissue and non-physiologic conditions. Periodic changes in either or both constituents of the baseline are determined and, when the changes correspond to a need for a new baseline, a new baseline is established.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 27, 2018
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Publication number: 20140378775
    Abstract: A unitary multilumen cranial bolt for use in multimodal monitoring of a plurality of physiological parameters in brain tissue incorporates a plurality of lumens, each lumen directing a catheter borne sensor through a bore hole in the cranium and into brain tissue of a patient. The lumens are configured to cause the catheters to splay outward as they enter the cranial cavity and reach their intended depth of penetration. Each lumen is associated with a guide. The guides are adapted for use with introducers that enable fragile and/or flexible sensors to be introduced into brain tissue. Each catheter borne sensor can be positioned and repositioned within brain tissue independently of all other sensors.
    Type: Application
    Filed: May 14, 2014
    Publication date: December 25, 2014
    Applicant: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Sammy M. Khalifa, Dean Honkonen
  • Patent number: 8915862
    Abstract: The system assesses the endothelial function of a subject. Particularly, peripheral tissue perfusion measurements taken in a subject are compared to reference perfusion data and the comparison yields the assessment of endothelial function. The reference may be data indicative of peripheral tissue perfusion in a healthy person. Also, peripheral tissue perfusion measurements taken in a subject when perfusion is in an unperturbed state (the reference) can be compared to perfusion measurements taken promptly after a challenge to normal or unperturbed tissue perfusion of the subject.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 23, 2014
    Assignee: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Publication number: 20140303513
    Abstract: An edema monitor uses patient-specific measurements of tissue conductivity and tissue perfusion and an empirically developed perfusion coefficient of thermal conductivity to obtain tissue intravascular water and tissue extravascular water components of tissue total water. Edema is an excess of tissue extravascular water. A value for edema is obtained by deducting from the obtained value for tissue extravascular water a normal value for tissue extravascular water.
    Type: Application
    Filed: April 1, 2014
    Publication date: October 9, 2014
    Applicant: Thermal Technologies, Inc
    Inventor: H. Frederick Bowman
  • Publication number: 20130218034
    Abstract: Methods and apparatus for determining blood flow in tissue are disclosed. The methods and apparatus are used to establish a baseline for both thermal properties of the tissue and non-physiologic conditions. Periodic changes in either or both constituents of the baseline are determined and, when the changes correspond to a need for a new baseline, a new baseline is established.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 22, 2013
    Applicant: Thermal Technologies Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Publication number: 20130218046
    Abstract: The system assesses the endothelial function of a subject. Particularly, peripheral tissue perfusion measurements taken in a subject are compared to reference perfusion data and the comparison yields the assessment of endothelial function. The reference may be data indicative of peripheral tissue perfusion in a healthy person. Also, peripheral tissue perfusion measurements taken in a subject when perfusion is in an unperturbed state (the reference) can be compared to perfusion measurements taken promptly after a challenge to normal or unperturbed tissue perfusion of the subject.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 22, 2013
    Applicant: Thermal Technologies Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Patent number: 8454525
    Abstract: Methods and apparatus for determining blood flow in tissue are disclosed. The methods and apparatus are used to establish a baseline for both thermal properties of the tissue and non-physiologic conditions. Periodic changes in either or both constituents of the baseline are determined and, when the changes correspond to a need for a new baseline, a new baseline is established.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: June 4, 2013
    Assignee: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Patent number: 8449475
    Abstract: The system assesses the endothelial function of a subject. Particularly, peripheral tissue perfusion measurements taken in a subject are compared to reference perfusion data and the comparison yields the assessment of endothelial function. The reference may be data indicative of peripheral tissue perfusion in a healthy person. Also, peripheral tissue perfusion measurements taken in a subject when perfusion is in an unperturbed state (the reference) can be compared to perfusion measurements taken promptly after a challenge to normal or unperturbed tissue perfusion of the subject.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: May 28, 2013
    Assignee: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Publication number: 20100241016
    Abstract: Methods and apparatus for determining blood flow in tissue are disclosed. The methods and apparatus are used to establish a baseline for both thermal properties of the tissue and non-physiologic conditions. Periodic changes in either or both constituents of the baseline are determined and, when the changes correspond to a need for a new baseline, a new baseline is established.
    Type: Application
    Filed: May 25, 2010
    Publication date: September 23, 2010
    Applicant: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Patent number: 7758511
    Abstract: Disclosed are methods and apparatus for determining blood flow in tissue. Particularly methods and apparatus are disclosed for establishing baseline thermal properties for the tissue and providing one or more steps for periodically determining changes in the tissue thermal properties that correspond to a need for a new baseline and establishing the new baseline.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: July 20, 2010
    Assignee: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Publication number: 20090216136
    Abstract: A technique is disclosed for determining blood flow in a living body by changing the thermal energy level in the venous blood flow path and determining temperatures in both the venous and arterial blood flow paths. Blood flow is calculated as a function of the change in energy level and the temperature differences in the venous and arterial blood flow paths.
    Type: Application
    Filed: March 2, 2009
    Publication date: August 27, 2009
    Applicant: Thermal Technologies, Inc.
    Inventor: H. Frederick Bowman
  • Publication number: 20030219719
    Abstract: Disclosed are methods and apparatus for determining blood flow in tissue. Particularly methods and apparatus are disclosed for establishing baseline thermal properties for the tissue and providing one or more steps for periodically determining changes in the tissue thermal properties that correspond to a need for a new baseline and establishing the new baseline.
    Type: Application
    Filed: April 4, 2003
    Publication date: November 27, 2003
    Applicant: Thermal Technologies, Inc.
    Inventors: H. Frederick Bowman, Gregory T. Martin
  • Patent number: 4741343
    Abstract: Oxygen partial pressure and temperature are measured in living tissue by inserting a thin probe into living tissue. The probe includes a plurality of spatially separated thermal sensors secured to the probe substrate. A plurality of oxygen sensors is positioned along the length of the probe substrate and each oxygen sensor is associated with and positioned adjacent to or is an integral part of one of the thermal sensors. Electrical parameters of the sensors located on the probe are measured and used to determine oxygen partial pressure and to determine temperature at each of a plurality of sites along the probe.
    Type: Grant
    Filed: December 22, 1986
    Date of Patent: May 3, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: H. Frederick Bowman, Stephen K. Burns, David J. Edell, James C. Weaver