Patents by Inventor H. James Hnatyszyn

H. James Hnatyszyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7285282
    Abstract: An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: October 23, 2007
    Assignee: University of Miami
    Inventors: Diana M. Lopez, Lynn M. Herbert, Mantley Dorsey, Jr., G√ľnter Kraus, H. James Hnatyszyn
  • Publication number: 20030166853
    Abstract: An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO: 1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.
    Type: Application
    Filed: April 2, 2002
    Publication date: September 4, 2003
    Inventors: Diana M. Lopez, Lynn M. Herbert, Mantley Dorsey, Gunter Kraus, H. James Hnatyszyn
  • Patent number: 5585646
    Abstract: Improved bio-electronic devices in which a layer of a polyhydroxy oligomer is provided between the surface of a semiconductor material and an electronically active biochemical molecule which is designed to be bound to the semiconductor surface to provide an electronic device. The layer of polyhydroxy oligomer functions as a biochemical stabilization layer to prevent denaturization of the electronically active biochemical molecule.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: December 17, 1996
    Assignee: The Regents of the University of California
    Inventors: Nir Kossovsky, Andrew Gelman, H. James Hnatyszyn, Samir Rajguru
  • Patent number: 5506420
    Abstract: Improved bio-electronic devices in which a layer of a polyhydroxy oligomer is provided between the surface of a semiconductor material and an electronically active biochemical molecule which is designed to be bound to the semiconductor surface to provide an electronic device. The layer of polyhydroxy oligomer functions as a biochemical stabilization layer to prevent denaturization of the electronically active biochemical molecule.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: April 9, 1996
    Assignee: The Regents of the University of California
    Inventors: Nir Kossovsky, Andrew Gelman, H. James Hnatyszyn, Samir Rajguru
  • Patent number: 5464634
    Abstract: A red blood cell surrogate which is composed of a nanocrystalline core particle to which an oxygen carrier such as hemoglobin is bound. An oxygen carrier anchor coating is provided between the nanocrystalline core particle and the oxygen carrier in order to provide binding of the oxygen carrier to the nanocrystalline core particle without denaturing the oxygen carrier or otherwise destroying its oxygen carrying capacity. The nanocrystalline core particle with the oxygen carrier bound thereto is coated with a layer of lipid and then an outer layer of a sugar or allosteric effector is applied.
    Type: Grant
    Filed: April 25, 1994
    Date of Patent: November 7, 1995
    Assignee: The Regents of the University of California
    Inventors: Nir Kossovsky, Andrew E. Gelman, H. James Hnatyszyn
  • Patent number: 5462751
    Abstract: A biologically active composition made up of biodegradable core particles which are coated with a layer that is designed to allow attachment of biologically active agents without denaturing them. The composition may further include an exterior targeting membrane which provides selective targeting to specific receptors.
    Type: Grant
    Filed: November 1, 1993
    Date of Patent: October 31, 1995
    Assignee: The Regeants of the University of California
    Inventors: Nir Kossovsky, H. James Hnatyszyn, Andrew Gelman
  • Patent number: 5460831
    Abstract: A biologically active composition for use in gene therapy and other transfection procedures. The composition is composed of nanocrystalline core particles which are coated with a layer that is designed to allow attachment of transfection agents (DNA/RNA segments or antisense fragments) without denaturing them. The composition may further include an exterior targeting membrane which provides selective targeting of the transfection agents to specific cell receptors.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: October 24, 1995
    Assignee: The Regents of the University of California
    Inventors: Nir Kossovsky, H. James Hnatyszyn, Andrew Gelman