Patents by Inventor H. John Kim

H. John Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING DISEASE USING ANALYSIS OF RNA
    Publication number: 20230072924
    Abstract: Methods for measuring subpopulations of ribonucleic acid (RNA) molecules are provided. In some embodiments, methods of generating a sequencing library from a plurality of RNA molecules in a test sample obtained from a subject are provided, as well as methods for analyzing the sequencing library to detect, e.g., the presence or absence of a disease.
    Type: Application
    Filed: October 24, 2022
    Publication date: March 9, 2023
    Inventors: Wenying Pan, Matthew Larson, H. John Kim, Arash Jamshidi
  • Methods for detecting disease using analysis of RNA
    Patent number: 11512349
    Abstract: Methods for measuring subpopulations of ribonucleic acid (RNA) molecules are provided. In some embodiments, methods of generating a sequencing library from a plurality of RNA molecules in a test sample obtained from a subject are provided, as well as methods for analyzing the sequencing library to detect, e.g., the presence or absence of a disease.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: November 29, 2022
    Assignee: GRAIL, LLC
    Inventors: Wenying Pan, Matthew Larson, H. John Kim, Arash Jamshidi
  • DIFFERENTIAL TAGGING OF RNA FOR PREPARATION OF A CELL-FREE DNA/RNA SEQUENCING LIBRARY
    Publication number: 20220010372
    Abstract: In various aspects, the present disclosure provides methods, compositions, reactions mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample. In some embodiments, RNA is treated so as to differentiate RNA sequences from DNA sequences derived from the same sample. In some embodiments, the RNA and DNA are cell-free polynucleotides.
    Type: Application
    Filed: September 24, 2021
    Publication date: January 13, 2022
    Inventors: Matthew Larson, H. John Kim, Nick Eattock, Arash Jamshidi
  • Differential tagging of RNA for preparation of a cell-free DNA/RNA sequencing library
    Patent number: 11180801
    Abstract: In various aspects, the present disclosure provides methods, compositions, reactions mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample. In some embodiments, RNA is treated so as to differentiate RNA sequences from DNA sequences derived from the same sample. In some embodiments, the RNA and DNA are cell-free polynucleotides.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: November 23, 2021
    Assignee: GRAIL, LLC
    Inventors: Matthew Larson, H. John Kim, Nick Eattock, Arash Jamshidi
  • METHODS FOR DETECTING DISEASE USING ANALYSIS OF RNA
    Publication number: 20200199671
    Abstract: Methods for measuring subpopulations of ribonucleic acid (RNA) molecules are provided. In some embodiments, methods of generating a sequencing library from a plurality of RNA molecules in a test sample obtained from a subject are provided, as well as methods for analyzing the sequencing library to detect, e.g., the presence or absence of a disease.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 25, 2020
    Inventors: Wenying Pan, Matthew Larson, H. John Kim, Arash Jamshidi
  • DIFFERENTIAL TAGGING OF RNA FOR PREPARATION OF A CELL-FREE DNA/RNA SEQUENCING LIBRARY
    Publication number: 20190062831
    Abstract: In various aspects, the present disclosure provides methods, compositions, reactions mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample. In some embodiments, RNA is treated so as to differentiate RNA sequences from DNA sequences derived from the same sample. In some embodiments, the RNA and DNA are cell-free polynucleotides.
    Type: Application
    Filed: October 31, 2018
    Publication date: February 28, 2019
    Inventors: Matthew Larson, H. John Kim, Nick Eattock, Arash Jamshidi
  • Differential tagging of RNA for preparation of a cell-free DNA/RNA sequencing library
    Patent number: 10144962
    Abstract: In various aspects, the present disclosure provides methods, compositions, reactions mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample. In some embodiments, RNA is treated so as to differentiate RNA sequences from DNA sequences derived from the same sample. In some embodiments, the RNA and DNA are cell-free polynucleotides.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: December 4, 2018
    Assignee: GRAIL, Inc.
    Inventors: Matthew Larson, H. John Kim, Nick Eattock, Arash Jamshidi
  • DIFFERENTIAL TAGGING OF RNA FOR PREPARATION OF A CELL-FREE DNA/RNA SEQUENCING LIBRARY
    Publication number: 20180002749
    Abstract: In various aspects, the present disclosure provides methods, compositions, reactions mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample. In some embodiments, RNA is treated so as to differentiate RNA sequences from DNA sequences derived from the same sample. In some embodiments, the RNA and DNA are cell-free polynucleotides.
    Type: Application
    Filed: June 29, 2017
    Publication date: January 4, 2018
    Inventors: Matthew Larson, H. John Kim, Nick Eattock, Arash Jamshidi