Patents by Inventor H. Lin

H. Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11435726
    Abstract: An industrial device supports device-level data modeling that pre-models data stored in the device with known relationships, correlations, key variable identifiers, and other such metadata to assist higher-level analytic systems to more quickly and accurately converge to actionable insights relative to a defined business or analytic objective. Data at the device level can be modeled according to modeling templates stored on the device that define relationships between items of device data for respective analytic goals (e.g., improvement of product quality, maximizing product throughput, optimizing energy consumption, etc.). This device-level modeling data can be provided to higher level systems together with their corresponding data tag values to high level analytic systems, which discovers insights into an industrial process or machine based on analysis of the data and its modeling data.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: September 6, 2022
    Assignee: Rockwell Automation Technologies, Inc.
    Inventors: Bijan Sayyarrodsari, Michael Pantaleano, Ka H Lin, Juergen K Weinhofer, Andrew J Ellis, Kyle Crum, Sujeet Chand, David Vasko, Subbian Govindaraj
  • Patent number: 11435812
    Abstract: A spare capacity status of each of multiple computing systems in a data center is monitored. Temporary workloads are assigned to these computing systems if there exists sufficient additional electrical power supply and capacity on power distribution lines. Thus, computing systems that are typically not productively used, such as those that are about to be decommissioned, have not yet been assigned for normal servicing, are reserved for special circumstances, or that are assigned to services that are currently in low demand, are temporarily used for productive data center purposes.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: September 6, 2022
    Assignee: Meta Platforms, Inc.
    Inventors: Kevin H. Lin, Min Ni, Ephraim Donghyun Park
  • Publication number: 20220195460
    Abstract: The disclosure provides vectors for treating cancers, method of producing such vectors and methods of use of the vectors.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 23, 2022
    Applicant: DENOVO BIOPHARMA LLC
    Inventors: Harry E. GRUBER, Douglas J. JOLLY, Amy H. LIN, Joan M, ROBBINS, Derek G. OSTERTAG
  • Patent number: 11332459
    Abstract: The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: May 17, 2022
    Assignee: TEIJIN PHARMA LIMITED
    Inventors: Michael D. Bartberger, Nagasree Chakka, Hua Gao, Angel Guzman-Perez, Daniel B. Horne, Zihao Hua, Madeleine Kieffer, Daniel C. H. Lin, Benjamin Charles Milgram, Jane Panteleev, Laurie Schenkel, John Stellwagen, Matthew Weiss, Ryan D. White, Wei Zhao
  • Publication number: 20220090132
    Abstract: The disclosure provides non-replicating viral vectors (RNV) for adoptive cell therapy. The RNVs can deliver chimeric antigen receptors to immune cells (e.g., T-Cells) in vivo.
    Type: Application
    Filed: January 6, 2020
    Publication date: March 24, 2022
    Inventors: Douglas J. Jolly, Joan M. Robbins, Amy H. Lin, Derek G. Ostertag, Cornelia Bentley, Sophie Viaud
  • Patent number: 11279949
    Abstract: This disclosure provides modified recombinant retroviruses comprisings containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide. The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: March 22, 2022
    Assignee: DENOVO BIOPHARMA LLC
    Inventors: Douglas J. Jolly, Amy H. Lin, Andrew Hofacre, Daniel J. Hogan, Derek G. Ostertag
  • Patent number: 11230719
    Abstract: The disclosure provides vectors for treating cancers, method of producing such vectors and methods of use of the vectors.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: January 25, 2022
    Assignee: DENOVO BIOPHARMA LLC
    Inventors: Harry E. Gruber, Douglas J. Jolly, Amy H. Lin, Joan M. Robbins, Derek G. Ostertag
  • Publication number: 20220002752
    Abstract: This disclosure provides modified recombinant retroviruses comprisings a transgene encoding a protein with a heterologous secretion signal, containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide, The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.
    Type: Application
    Filed: November 13, 2019
    Publication date: January 6, 2022
    Applicant: DENOVO BIOPHARMA LLC
    Inventors: Amy H. LIN, Douglas J. JOLLY
  • Patent number: 11193927
    Abstract: Methods, devices, and systems for automated cellular analysis of a body fluid sample are disclosed. The methods, devices, and systems apply watershed transform to data, generated by flowing a body fluid sample through a flow cytometer, to determine threshold(s) to be used for analysis of the data.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: December 7, 2021
    Assignee: Abbott Laboratories
    Inventors: Wenjing Li, Emily H. Lin, Jiong Wu
  • Publication number: 20210361691
    Abstract: This disclosure relates to replication competent viral vectors for treating cell proliferative disorders. The disclosure further relates to the use of such replication competent viral vectors for delivery and expression of a heterologous nucleic acid in normal and diseased tissues and methods and compositions that facilitate such delivery and expression to tissues in vivo and in vitro. The disclosure further relates to replication competent retroviral vectors for these uses and in conjunction with methods and compositions that facilitate in vivo therapeutics.
    Type: Application
    Filed: March 1, 2021
    Publication date: November 25, 2021
    Applicant: DENOVO BIOPHARMA, LLC
    Inventors: Harry E. Gruber, Douglas J. Jolly, Derek G. Ostertag, Ryan S. Burnett, Amy H. Lin, Tiffany Huang, Joan M. Robbins
  • Patent number: 11163474
    Abstract: Provided are a method, system, and computer program product in which a storage controller receives a request from a host to migrate a source dataset comprising a plurality of tracks to a cloud storage. A plurality of readers are initiated to read the plurality of tracks of the source dataset in parallel, wherein each of the plurality of readers reads different tracks from the source dataset and transmits the tracks that are read from the source dataset to a migrator. For each track received by the migrator from the plurality of readers, the track is appended sequentially to a migrate dataset to be stored in the cloud storage. Metadata that indicates a mapping of tracks of the source dataset to tracks of the migrate dataset is generated.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 2, 2021
    Assignee: International Business Machines Corporation
    Inventors: Qiang Xie, Hui Zhang, Edward H. Lin
  • Patent number: 11157192
    Abstract: A storage controller receives a request from a host to generate a source dataset by downloading a cloud object corresponding to the source dataset from a cloud storage. A plurality of writers that execute in parallel determines from metadata that indicates a mapping of tracks of the source dataset to tracks of the cloud object, which track of the cloud object corresponds to which track of the source dataset, to generate the source dataset from the cloud object for storing in a storage drive coupled to the storage controller.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: October 26, 2021
    Assignee: International Business Machines Corporation
    Inventors: Qiang Xie, Hui Zhang, Edward H. Lin
  • Patent number: 11086559
    Abstract: Provided are techniques for cloud based store and restore with copy services. A store command to transfer data from one or more tracks of a volume to cloud storage is received. With track services, data for the one or more tracks in the volume is retrieved by emulating a host read. With a cloud data movement engine, the data for the one or more tracks is converted to data for one or more objects. With the cloud data movement engine, the one or more objects are stored in the cloud storage.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: August 10, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Matthew R. Craig, Edward H. Lin, Beth A. Peterson, Qiang Xie
  • Patent number: 11065311
    Abstract: This disclosure provides a retroviral replicating vector for gene delivery comprising a therapeutic cassette containing at least one mini-promoter linked to a gene to be expressed.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: July 20, 2021
    Assignee: DENOVO BIOPHARMA LLC
    Inventors: Harry E. Gruber, Douglas J. Jolly, Amy H. Lin, Christopher R. Logg, Noriyuki Kasahara
  • Publication number: 20210218368
    Abstract: A solid-state device chip including diodes (generating a higher or lower frequency output through frequency multiplication or mixing of the input frequency) and a novel on-chip diplexing design that allows combination of two or more multiplier or mixer structures operating at different frequency bands within the 50-5000 GHz range within a same chip and/or waveguide. The on-chip diplexing design consists of a single-substrate multiplier chip with two or more multiplying structures each one containing 2 or more Schottky diodes. The diodes in each structure are tuned to one portion of the target frequency band, resulting in the two or more structures working together as a whole as a large broadband multiplier or mixer. Thus, an increase in bandwidth from 10-15% (current state-of-the-art) to at least 40% is achieved. Depending on the target frequencies, each subset of diodes within the chip can be designed to work either as a doubler or a tripler.
    Type: Application
    Filed: November 9, 2020
    Publication date: July 15, 2021
    Applicant: California Institute of Technology
    Inventors: Jose Vicente Siles Perez, Choonsup Lee, Robert H. Lin, Alejandro Peralta
  • Patent number: 11023431
    Abstract: In one embodiment of split data migration in accordance with the present description, to migrate the data of a volume or other data unit which has been previously mirrored from a primary data storage system to a secondary data storage system, the data unit is split into two or more parts. One part is migrated from the primary data storage system to a migration target storage system, and another part is migrated from the secondary data storage system, to the same, common migration target storage system. In this manner, the migration workload of migrating a unit of data may be split between the primary and secondary storage systems, reducing the impact of migration data processing upon the primary storage system and reducing migration time. Other features and aspects may be realized, depending upon the particular application.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: June 1, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Edward H. Lin, Joseph M. Swingler, Robert S. Gensler, Jr.
  • Publication number: 20210158951
    Abstract: A system obtains patient data, de-identifies each patient with a unique patient key (UPK) and joins the patient data without linking to personal identities of the patients. The system further receives a search query from a user device, identifies a group of UPKs associated with patient data that satisfies criteria of the search query based on values for associated healthcare attributes, and clusters the group of UPKs with respect to healthcare events. The system then ranks the healthcare events of the clusters and sends a query result including healthcare data that is generated based on the ranking, where the query result conceals any personal identity of any of the patients.
    Type: Application
    Filed: January 6, 2021
    Publication date: May 27, 2021
    Inventors: David A. Vivero, Jorge A. Caballero, Abraham M. Othman, Farid Jamshidian, Eithon Michael Galinato Cadag, Abhinav Chowdary Yarlagadda, James Lyon Fingal, Nicholas C. Dunkman, Kunal Dhiren Shah, Willard Kirk Strauser, Michael H. Lin, Mary Audrey Hampden, Sumul Mahendra Shah, Rebecca Ackermann
  • Publication number: 20210130866
    Abstract: Herein is provided a simple, reliable and accurate method for cellular analysis on hematology analyzers. In various aspects, the methods provide separation and/or differentiation between red blood cells (RBCs) and white blood cells (WBCs) by utilizing a fluorescent dye to selectively stain WBCs such that they emit stronger fluorescence signals. The method provides optimal detection limits on WBCs and RBCs, thereby allowing analysis of samples with sparse cellular concentrations. As few as one reagent may be used to prepare a single dilution for body fluid analysis, in order to simplify the body fluid analysis. Minimal damage to WBCs is attained using the lysis-free approach described in aspects of the disclosure.
    Type: Application
    Filed: August 25, 2020
    Publication date: May 6, 2021
    Inventors: Jiong Wu, Emily H. Lin, Jihping Yang
  • Publication number: 20210097456
    Abstract: A smart gateway platform leverages pre-defined industrial expertise to identify limited subsets of available industrial data deemed relevant to a desired business objective, and to collect and model this relevant data to apply useful constraints on subsequent artificial intelligence or machine learning analytics applied to the data. This approach can reduce the data space to which AI analytics are applied and assist data analytic systems to more quickly derive valuable insights and business outcomes. In some embodiments, the smart gateway platform can operate within the context of a multi-level industrial analytic system, feeding pre-modeled data to one or more AI or machine learning systems executing on one or more different levels of an industrial enterprise. The multi-level industrial analytic system can also further refine modeled industrial data as the data moves upward through the system (e.g., from the device level to higher levels).
    Type: Application
    Filed: September 30, 2019
    Publication date: April 1, 2021
    Inventors: Bijan Sayyarrodsari, Michael Pantaleano, Ka H Lin, Juergen K Weinhofer, Andrew J Ellis, Kyle Crum, Sujeet Chand, David Vasko, Subbian Govindaraj
  • Publication number: 20210096551
    Abstract: An industrial data broker system receives contextualized industrial data from one or more industrial devices that support data modeling at the device level. The received industrial data is augmented with contextualization metadata that defines correlations between the data relevant to an analytical objective, and labels specifying analytic topics to which each data item is relevant. The broker system allows external systems, such as analytic systems, to subscribe to topics of interest, and streams a subset of contextualized device data relevant to the topic of interest to the external system for analysis.
    Type: Application
    Filed: September 30, 2019
    Publication date: April 1, 2021
    Inventors: Bijan Sayyarrodsari, Michael Pantaleano, Ka H. Lin, Juergen K. Weinhofer, Andrew J. Ellis, Kyle Crum, Sujeet Chand, David Vasko, Subbian Govindaraj