Abstract: The location of a printing device is determined. Environmental conditions in which the printing device operated when printing a print job are determined based on the determined location. An environmental adjustment factor for the printing device is determined based on the determined environmental conditions. A predicted print material usage of the printing device in printing the print job is adjusted based on the determined environmental adjustment factor.

Abstract: An image forming apparatus includes a development cartridge having a developing roller. A coupler for the image forming apparatus includes a shaft and a coupling structure to rotate the developing roller. The coupling structure is disposed at an end part of the shaft, is movable along an axial direction of the shaft and coupleable with another coupling structure of a print engine of the image forming apparatus. The coupling structure includes a body, a magnet disposed in the body to cause the coupling structure to be attracted to the another coupling structure so that the coupling structure is aligned with the another coupling structure, and a plurality of protrusions which protrude from the body in the axial direction to engage with the another coupling structure, the plurality of protrusions having at least one side with an inclined face.

Abstract: In response to detecting that a remaining supply of print material of a first cartridge has reached a first threshold, a printing device transmits a request. In response to detecting that a second cartridge has replaced the first cartridge, the printing device determines whether the remaining supply had reached a second threshold and whether a token permitting usage of the second cartridge was received responsive to the request. In response to determining that the remaining supply had reached the second threshold and that the token was received, the printing device prints with print material from the second cartridge.

Abstract: The number of days until a consumable item of a printing device reaches end of life is predicted based on a usage scenario of the printing device. An expected fulfillment time period is subtracted from the predicted number of days to determine a number of days until a fulfillment event occurs. A threshold remaining life of the consumable item is correlated with the number of days until the fulfillment event occurs. That the remaining life of the consumable item has reached the threshold remaining life is detected, and fulfillment of a replacement consumable item to replace the consumable item is responsively initiated.

Abstract: An occlusive device includes a covering component configured to modulate passage of blood or thrombus therethrough, and an occlusion frame that includes a plurality of elongate occlusion frame members. The elongate occlusion frame members are arranged to form a generally disc-shaped member. The occlusion frame is at least partially covered by the covering component. The device further includes an anchor frame that includes a plurality of elongate anchor frame members. The device further includes a first hub component from which the elongate frame members extend, and a second hub component from which the elongate frame members extend.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a plurality of absorbable filaments arranged in a support structure and configured degrade within a defined time period and a membrane arranged about the plurality of absorbable filaments and configured to contain fragments of the plurality of absorbable filaments in response to a fracture or degradation of a filament.

Abstract: A composition comprising direct, indirect and related pathway endocannabinoid mimetic compounds and methods of using the composition.

Abstract: The present disclosure provides a non-autologous product that is a mixture of two or more cells or tissue cultures of fibroblast, or extracts from cultures, or media cultures, isolated from separate individuals, either homogeneous or heterogeneous. The cells or factors are blended together in a product that imparts desired characteristics to the skin of a recipient who is not a source of the mixture. The present disclosure also relates to methods of making and using and/or culturing the fibroblasts including to optimize the potency of the mixture to impart one or more the desired characteristics to the skin of a recipient.

Abstract: An optimization of electrical characteristics for treatments of tumor or other abnormal cells in culture with sub-microsecond, high-electric field electrical pulses is disclosed. The voltages, pulse widths, and number of pulses are chosen such that the treatment energy is 10-20 J/mL. That is, U=n*?t*V*I/volume is 10-20 J/mL, in which n is the number of pulses, ?t is the duration of each pulse, V is the voltage, I is current, and volume is the area of parallel electrodes times the distance between them. V divided by the distance between the electrodes can be in an effective range of 6 kV/cm to 30 kV/cm, 60 kV/cm, 100 kV/cm, or higher intensities. Rows of needle electrodes, blade electrodes, or other configurations of electrodes can approximate parallel electrodes.

Abstract: Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the use of multiple light sources for treating skin with or without the use of a topical compositions or photomodulation enhancing agents. Dual light emitting diodes may, for example, be used at relatively low power (less than about 10 J/cm2) to photomodulate skin or living tissue to reduce wrinkles, fine lines, acne, acne bacteria, and other skin disorders.

Abstract: There is provided a topical skin composition directed to one or more desired benefits. The composition includes one or more proteins selected based on the desired skin benefit to be derived by application of the topical skin composition. In one embodiment, each protein is from one donor group having two or more individuals. In another embodiment, the protein is from two or more donor group.

Abstract: Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the reduction of acne and acne related bacteria using low-intensity light therapy. In an illustrative embodiment, skin containing acne bacteria is treated with a series of pulses of light from a light emitting diode. The LED has a dominant emissive wavelength of about 660 nm and an energy output of about 4 m W. The acne bacteria-containing tissue is exposed to pulses from the light source about 100 times for about 250 milliseconds per pulse, with an interpulse interval of about 100 milliseconds.

Abstract: Disclosed is a system and method for treatment of cells and, in particular, visual pathway disorders. More particularly, the disclosed invention is directed toward the photomodulation and/or photorejuvenation of retinal epithelial cells, to treat a variety of vision disorders. The process of treating retinal cells to reduce or reverse the effects of visual pathway disorders employs a narrowband source of multichromatic light applied to the retinal cells to deliver a very low energy fluence.

Abstract: A method including photomodulating mammalian tissue with more than one light source of narrowband, multi chromatic electromagnetic radiation, wherein at least one light source emits radiation at a wavelength corresponding to yellow light and at least one light source emits radiation corresponding to infra-red light, wherein the ratio of the intensity of yellow light to infra-red light is about 4:1.

Abstract: Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the use of multiple light sources for treating skin with or without the use of a topical compositions or photomodulation enhancing agents. Dual light emitting diodes may, for example, be used at relatively low power (less than about 10 J/cm2) to photomodulate skin or living tissue to reduce wrinkles, fine lines, acne, acne bacteria, and other skin disorders.

Abstract: A method including photomodulating mammalian tissue with more than one light source of narrowband, multi chromatic electromagnetic radiation, wherein at least one light source emits radiation at a wavelength corresponding to yellow light and at least one light source emits radiation corresponding to infra-red light, wherein the ratio of the intensity of yellow light to infra-red light is about 4:1.

Abstract: The present disclosure provides a non-autologous product that is a mixture of two or more cells or tissue cultures of fibroblast, or extracts from cultures, or media cultures, isolated from separate individuals, either homogeneous or heterogeneous. The cells or factors are blended together in a product that imparts desired characteristics to the skin of a recipient who is not a source of the mixture. The present disclosure also relates to methods of making and using and/or culturing the fibroblasts including to optimize the potency of the mixture to impart one or more the desired characteristics to the skin of a recipient.

Abstract: Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the use of multiple light sources for treating skin with or without the use of a topical compositions or photomodulation enhancing agents. Dual light emitting diodes may, for example, be used at relatively low power (less than about 10 J/cm2) to photomodulate skin or living tissue to reduce wrinkles, fine lines, acne, acne bacteria, and other skin disorders.

Abstract: Described herein are the results of comprehensive genetic expression and other molecular analysis of the effect of antioxidants on biological systems, including specifically different human cells. Based on these analyses, methods and compositions are described for modifying or influencing the lifespan of cells, tissues, organs, and organisms. In various embodiments, there are provided methods for modulating the activity of the gene maintenance process in order to influence the length and/or structural integrity of the telomere in living cells, as well as methods for modulating the rate/efficiency of the cellular respiration provided by the mitochondria, mitochondrial biogenesis, and maintenance of the mitochondrial membrane potential.

Abstract: Provided herein are methods of culturing cells in vitro in order to exploit the biochemical production ability of the cells to make metabolites that are evaluated and harvested for their biological effects. Also provided are systems for evaluating extracts from such cultured cells to characterize their biological activity(s), particularly with regard to impact on health, wellbeing, longevity, DNA maintenance, mitochondrial health and/or biogenesis, and so forth. Biologically active extracts, components thereof, and compositions (such as cosmetic or pharmaceutical preparations) made comprising such, are also provided.