Abstract: The invention relates to systems and methods for calibrating and using resistance temperature detectors. In one embodiment, the system includes a calibration circuit comprising a resistance temperature detector in a bridge circuit with at least one potentiometer, and a programmable gain amplifier coupled to the bridge circuit. Embodiments of the invention further comprise methods for calibrating the bridge circuit and the programmable gain amplifier for use with the resistance temperature detector and methods for determining the self heating voltage of the bridge circuit.

Abstract: Gaskets for use with a bell and spigot coupling system are disclosed herein. The gasket comprises an elastomeric member having a front edge, a first section, and a second section. Axial forces generated by the insertion of the spigot to the first section of the elastomeric member displace the first section of the elastomeric member in an axial and radial direction.

Abstract: In an exemplary embodiment, a temperature sensor and a 4-20 mA transmitter on a single flexible circuit subassembly with a separate housing suitable for use in industrial control or HVAC applications. In a preferred embodiment, a narrow flex circuit substrate includes a silicon diode-based surface-mount sensor at a sensor end, a surface-mount programmable transmitter IC on a flex circuit substrate in the transmitter section, conductive traces connecting the sensor to the transmitter IC, and two conductive pads at an output end for connecting the 4-20 mA output to a pair of external wires. Additional traces on the flex subassembly are provided for testing and programming the transmitter IC and sensor. The sensor end of the flex subassembly is mounted in a metal sensor tube, filled and sealed in the same manner as RTD or thermistor sensors with leads are currently assembled for use in industrial control or HVAC applications.

Abstract: The invention relates to methods and devices for control of an integrated thin-film device with a plurality of microfluidic channels. In one embodiment, a microfluidic device is provided that includes a microfluidic chip having a plurality of microfluidic channels and a plurality of multiplexed heater electrodes, wherein the heater electrodes are part of a multiplex circuit including a common lead connecting the heater electrodes to a power supply, each of the heater electrodes being associated with one of the microfluidic channels. The microfluidic device also includes a control system configured to regulate power applied to each heater electrode by varying a duty cycle, the control system being further configured to determine the temperature of each heater electrode by determining the resistance of each heater electrode.

Abstract: A protective coating for a metal substrate is provided that is light, durable, galvanically protective, and easily applied at the site of manufacture. The coating has at least two layers, one of which is a galvanizing layer and one of which is a micro-composite of a galvanic metal and a non-conducting material, such as polymer. Such coatings are useful for example to protect pipes or other metal surfaces in corrosive environments. Methods of producing the coating are provided, including methods that use advanced spraying techniques to provide very thin but consistent layers. Using the advanced spraying methods the composite layer can be created by co-spraying the galvanic metal and the nonconductive material onto the surface of the galvanic coating. Optionally, an outer coat of insulating material can be applied to provide further protection to the surface.

Abstract: A conduit coupling system, sealing device, bell and method of use are disclosed herein. The system comprises at least two piping components, and a sealing device. A first component has a bell and a second component has a spigot, the spigot is adapted to mate with the bell. The bell comprises a first end and a second end, the first end coupled to the first component. The bell has a concave annular inner surface and a diameter of the annular inner surface adjacent to the first end of the bell is greater than a diameter of the annular inner surface adjacent to the second end of the bell. The sealing device comprises a locking segment comprising a convex outer surface and a K-type gasket coupled to a locking segment or a non-restraining anti-extrusion segment. The sealing device is adapted to fit between the bell and the spigot.

Abstract: A conduit coupling system, sealing device, bell and method of use are disclosed herein. The system comprises at least two piping components, and a sealing device. A first component has a bell and a second component has a spigot, the spigot is adapted to mate with the bell. The bell comprises a first end and a second end, the first end coupled to the first component. The bell has a concave annular inner surface and a diameter of the annular inner surface adjacent to the first end of the bell is greater than a diameter of the annular inner surface adjacent to the second end of the bell. The sealing device comprises a locking segment comprising a convex outer surface and a K-type gasket coupled to a locking segment or a non-restraining anti-extrusion segment. The sealing device is adapted to fit between the bell and the spigot.

Abstract: The present invention, in one aspect, provides methods and systems for controlling slugs using temperature dependent fluorescent dyes. In some embodiments, the present invention uses one or more techniques to enhance the visibility of slugs, enhance a system's ability to differentiate between slugs, and enhance a system's ability to identify the positions of slugs.

Abstract: The present invention relates generally to systems and methods for the rapid serial processing of multiple nucleic acid assays. More particularly, the present invention provides for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g.

Abstract: Gaskets for use with a bell and spigot coupling system are disclosed herein. The gasket comprises an elastomeric member having a front edge, a first section, and a second section. Axial forces generated by the insertion of the spigot to the first section of the elastomeric member displace the first section of the elastomeric member in an axial and radial direction.

Abstract: A conduit coupling system, sealing device, bell, and method of use are disclosed herein. The system comprises at least two piping components, and a sealing device. A first component has a bell and a second component has a spigot, the spigot is adapted to mate with the bell. The bell comprises a first end and a second end, the first end coupled to the first component. The bell has a concave annular inner surface and a diameter of the annular inner surface adjacent to the first end of the bell is greater than a diameter of the annular inner surface adjacent to the second end of the bell. The sealing device comprises a locking segment comprising a convex outer surface and a K-type gasket coupled to a locking segment or a non-restraining anti-extrusion segment. The sealing device is adapted to fit between the bell and the spigot.

Abstract: The subject invention relates to implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants.

Abstract: Methods for determining structural integrity of a bone within the spine of a patient, the bone having a first aspect and a second aspect, wherein the second aspect separated from the first aspect by a width and located adjacent to a spinal nerve. The methods involve (a) applying an electrical stimulus to the first aspect of the bone; (b) electrically monitoring a muscle myotome associated with the spinal nerve to detect if an onset neuro-muscular response occurs in response to the application of the electrical stimulus to the first aspect of the bone; (c) automatically increasing the magnitude of the electrical stimulus to until the onset neuro-muscular response is detected; and (d) communicating to a user via at least one of visual and audible means information representing the magnitude of the electrical stimulus which caused the onset neuro-muscular response.

Abstract: A conduit coupling system, sealing device, bell and method of use are disclosed herein. The system comprises at least two piping components, and a sealing device. A first component has a bell and a second component has a spigot, the spigot is adapted to mate with the bell. The bell comprises a first end and a second end, the first end coupled to the first component. The bell has a concave annular inner surface and a diameter of the annular inner surface adjacent to the first end of the bell is greater than a diameter of the annular inner surface adjacent to the second end of the bell. The sealing device comprises a locking segment comprising a convex outer surface and a K-type gasket coupled to a locking segment or a non-restraining anti-extrusion segment. The sealing device is adapted to fit between the bell and the spigot.

Abstract: Methods for determining structural integrity of a bone within the spine of a patient, the bone having a first aspect and a second aspect, wherein the second aspect separated from the first aspect by a width and located adjacent to a spinal nerve. The methods involve (a) applying an electrical stimulus to the first aspect of the bone; (b) electrically monitoring a muscle myotome associated with the spinal nerve to detect if an onset neuro-muscular response occurs in response to the application of the electrical stimulus to the first aspect of the bone; (c) automatically increasing the magnitude of the electrical stimulus to until the onset neuro-muscular response is detected; and (d) communicating to a user via at least one of visual and audible means information representing the magnitude of the electrical stimulus which caused the onset neuro-muscular response.

Abstract: In one aspect, the present invention provides a systems and methods for the real-time amplification and analysis of a sample of DNA.

Abstract: A system is disclosed for integrated electronic mail, voice mail, and fax mail messaging. A common message format is defined for use by an electronic mail service and a telecommunications service so electronic mail messages that may include voice and fax mail attachments may be exchanged between the services. Message senders and receivers may choose from a variety of filter and forward options that allow them to manage their communications and specify a preference for receiving messages at the electronic mail or telecommunications service. Forwarding and conversion of messages is performed automatically. The options are used to define a set of rules to be applied to inbound and outbound messages so that messages are sent and received in accordance with the preferences of the senders and receivers.

Abstract: A method of use of a conduit coupling system, sealing device, and bell are disclosed herein. The method comprises positioning a sealing device inside a bell coupled to one end of a first conduit, inserting a spigot of a second conduit through the sealing device inside the bell, wherein the sealing device is adapted to move axially within the bell in the direction of the insertion of the spigot and in a radial direction from a centerline of the conduit, and partially removing the spigot from the bell, wherein a segment of the sealing device engages the outer surface of the spigot end as the spigot end is partially removed from the bell. The bell comprises a first end and a second end, the first end coupled to the first conduit. The bell has a concave annular inner surface and a diameter of the annular inner surface adjacent to the first end of the bell is greater than a diameter of the annular inner surface adjacent to the second end of the bell.

Abstract: An electrical junction assembly for a wiring harness (10) couples one or more branch wires (18) to a main trunk line (12). The junction assembly includes a housing (16) having an internal cavity into which is received first (34) and second (36) trunk terminals which interlock with one another and establish electrical conductivity therethrough. A branch wire (18) is inserted into the housing (16) through a branch opening (28). The branch wire (18) has a branch terminal (48) on its end which is adapted to mechanically connect to the interlocked first (34) and second (36) trunk terminals, thereby establishing electrical conductivity between the branch wire (18) and the main trunk line (12). A mounting member (56) is formed integrally on the housing (16) to provide a secure connection to a suitable mounting structure (58). A hook (40) within the cavity in the housing (16) automatically engages and securely retains the second trunk terminal (36) when inserted into a full operative position.

Abstract: Systems for determining structural integrity of a bone within the spine of a patient, the bone having a first aspect and a second aspect, wherein the second aspect separated from the first aspect by a width and located adjacent to a spinal nerve. A stimulator is configured to generate an electrical stimulus to be applied to the first aspect of the bone. A monitor is configured to electrically monitor a muscle myotome associated with the spinal nerve to detect if an onset neuro-muscular response occurs in response to the application of the electrical stimulus to the first aspect of the bone. An adjuster is configured to automatically increase the magnitude of the electrical stimulus to until the onset neuro-muscular response is detected. Lastly, a communicator is configured to communicate to a user via at least one of visual and audible means information representing the magnitude of the electrical stimulus which caused the onset neuro-muscular response.