Patents by Inventor H. Paul Redmond

H. Paul Redmond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10736902
    Abstract: A method of treating a patient suffering from TNBC by a multidisciplinary method involving treating the patient with a plurality of the following treatments: i) one or more checkpoint inhibitors; ii) hyperthermia treatment; iii) low dose chemotherapy; iv) Interleukin-2 (IL-2); and v) a compound selected from the group consisting of taurolidine, taurultam, oxathiazin-like compounds, and combinations thereof.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: August 11, 2020
    Assignee: GEISTLICH PHARMA AG
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20190091233
    Abstract: A method of treating a patient suffering from TNBC by a multidisciplinary method involving treating the patient with a plurality of the following treatments: i) one or more checkpoint inhibitors; ii) hyperthermia treatment; iii) low dose chemotherapy; iv) Interleukin-2 (IL-2); and v) a compound selected from the group consisting of taurolidine, taurultam, oxathiazin-like compounds, and combinations thereof.
    Type: Application
    Filed: March 17, 2017
    Publication date: March 28, 2019
    Applicant: GEISTLICH PHARMA AG
    Inventors: H. Paul REDMOND, Rolf W. PFIRRMANN
  • Patent number: 9012444
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: April 21, 2015
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20110172213
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: March 21, 2011
    Publication date: July 14, 2011
    Applicant: Ed. Geistlich Soehne AG fuer chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 7914817
    Abstract: Patients suffering from inflammatory bowel disease such as Crohn's disease or ulcerative colitis are treated either orally or intravenously with methylol transfer agents, such as taurolidine and/or taurultam. These agents can be used in combination with other drugs thereby allowing the use of smaller amounts of the other drugs and limiting unwanted side effects.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: March 29, 2011
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 7910580
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: March 22, 2011
    Assignee: Ed. Geistlich Soehne AG Fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 7892530
    Abstract: Tumor metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of Interleukin-2 and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: February 22, 2011
    Assignee: ED. Geistlich Soehne AG Fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20080171738
    Abstract: A method of treating a patient with breast cancer includes administering to the patient a breast cancer cell proliferation-inhibiting amount of a methylol-containing compound such as taurolidine, taurultam or a mixture thereof.
    Type: Application
    Filed: January 2, 2008
    Publication date: July 17, 2008
    Applicant: ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 7345039
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: March 18, 2008
    Assignee: Ed. Geistlich Soehne AG fuer chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 7151099
    Abstract: Taurolidine and/or taurultam is administered during and after surgical removal of a cancerous tumor to treat abdominal cancer.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: December 19, 2006
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20040087579
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 6, 2004
    Applicant: Ed. Geistlich Soehne fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Patent number: 6641571
    Abstract: Patients undergoing cardiopulmonary bypass surgery are treated perioperatively with methylol transfer agents, such as Taurolidine. Patients undergoing crystalloid cardioplegia who are treated with taurolidine show reduced levels of IL-6 and increased levels of IL-10 when compared to crystalloid cardioplegia patients administered a placebo. Crystalloid cardioplegia patients administered Taurolidine also show reduced levels of IL-6 and increased levels of IL-10 when compared to blood cardioplegia patients who were administered Taurolidine.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: November 4, 2003
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20030119824
    Abstract: Patients suffering from inflammatory bowel disease such as Crohn's disease or ulcerative colitis are treated either orally or intravenously with methylol transfer agents, such as taurolidine and/or taurultam. These agents can be used in combination with other drugs thereby allowing the use of smaller amounts of the other drugs and limiting unwanted side effects.
    Type: Application
    Filed: December 19, 2002
    Publication date: June 26, 2003
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20030092707
    Abstract: A method of treating a patient with breast cancer includes administering to the patient a breast cancer cell proliferation-inhibiting amount of a methylol-containing compound such as taurolidine, taurultam or a mixture thereof.
    Type: Application
    Filed: October 15, 2002
    Publication date: May 15, 2003
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20030027818
    Abstract: A method of inducing apoptotic death of a neoplastic cell, whereby the neoplastic cell is contacted with an apoptosis-inducing amount of a methylol-containing compound. This method is useful for treating both primary and metastatic cancers. A preferred embodiment includes administering a :4 methylol transfer agent to the mammal, at a total daily dose of from about 2 g to about 60 g, the administration including at least two dosing cycles, each dosing cycle including an infusion phase of about 1 to 8 days, and a non-administration phase of about 1 to 14 days. Another embodiment includes treating liver cancer by administration of a solution of a methylol transfer agent directly to the liver via a hepatic vessel.
    Type: Application
    Filed: March 29, 2002
    Publication date: February 6, 2003
    Inventors: H. Paul Redmond, Hanns Moehler, Ruediger Stendel, Rolf W. Pfirrmann
  • Publication number: 20020111328
    Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: November 27, 2001
    Publication date: August 15, 2002
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20020098164
    Abstract: Tumor metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of Interleukin-2 and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.
    Type: Application
    Filed: October 23, 2001
    Publication date: July 25, 2002
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20020091123
    Abstract: Taurolidine and/or taurultam is administered during and after surgical removal of a cancerous tumor to treat abdominal cancer.
    Type: Application
    Filed: October 9, 2001
    Publication date: July 11, 2002
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20020035996
    Abstract: Patients undergoing cardiopulmonary bypass surgery are treated perioperatively with methylol transfer agents, such as Taurolidine. Patients undergoing crystalloid cardioplegia who are treated with taurolidine show reduced levels of IL-6 and increased levels of IL-10 when compared to crystalloid cardioplegia patients administered a placebo. Crystalloid cardioplegia patients administered Taurolidine also show reduced levels of IL-6 and increased levels of IL-10 when compared to blood cardioplegia patients who were administered Taurolidine.
    Type: Application
    Filed: January 4, 2001
    Publication date: March 28, 2002
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann
  • Publication number: 20020004502
    Abstract: Patients suffering from inflammatory bowel disease such as Crohn's disease or ulcerative colitis are treated either orally or intravenously with methylol transfer agents, such as taurolidine and/or taurultam. These agents can be used in combination with other drugs thereby allowing the use of smaller amounts of the other drugs and limiting unwanted side effects.
    Type: Application
    Filed: January 4, 2001
    Publication date: January 10, 2002
    Inventors: H. Paul Redmond, Rolf W. Pfirrmann