Patents by Inventor H. William Harris

H. William Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for raising pre-adult anadromous fish
    Patent number: 6463883
    Abstract: The invention relates to methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: October 15, 2002
    Assignee: MariCal, LLC
    Inventors: H. William Harris, Jr., David R. Russell, Jacqueline Nearing, Marlies Betka
  • Growing marine fish in freshwater
    Patent number: 6463882
    Abstract: The invention relates to methods, compositions and kits for raising marine fish in freshwater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significant increased level of the PVCR modulator in serum of the marine fish.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: October 15, 2002
    Assignee: MariCal, LLC
    Inventors: H. William Harris, Jr., David R. Russell, Jacqueline Nearing, Marlies Betka
  • Polycation-sensing receptor in aquatic species and methods of use
    Patent number: 6337391
    Abstract: Polycation-sensing receptors present in aquatic species and methods of regulating polycation-sensing receptor-mediated functions in aquatic species are described.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: January 8, 2002
    Assignee: Brighams & Women's Hospital
    Inventors: H. William Harris, Edward M. Brown, Steven C. Hebert
  • Method for determining the diuretic potency of candidate drugs as inhibitors of the antidiuretic hormone-elicited water channel
    Patent number: 5106610
    Abstract: A method for determining the diuretic potency of candidate drugs as inhibitors of ADH-elicited water channels is disclosed. In a preferred embodiment, such diuretic potency of candidate drugs is determined by suspending vesicles containing ADH water channels in an aqueous suspending medium, incorporating the candidate into the suspension, rapidly changing the pH of the suspending medium and thereafter detecting the proton permeability of the water channels. The proton permeability in the presence of the candidate drug can then be compared to the proton permeability of water channels under similar conditions without the presence of the candidate drug to determine the diuretic potency of the candidate drug to inhibit ADH-elicited water channels.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: April 21, 1992
    Assignee: Childrens Medical Center Corporation
    Inventors: H. William Harris, Mark L. Zeidel