Abstract: The present disclosure relates to a novel peptide derivative, etc., the peptide derivative being a partially modified adiponectin receptor peptide which, compared to conventional adiponectin receptor peptides, has higher stability, superior p-AMPK activity, and improved physical properties and activity and thus offers advantages when formulated into a drug. Therefore, the peptide derivative of the present invention can be used to prevent or treat inflammatory skin diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, to prevent or alleviate aging, sensitive skin, or wrinkles, or to enhance moisturization.

Abstract: The present invention relates to a novel peptoid derivative and the like. The peptoid derivative is obtained by partially modifying an adiponectin receptor peptide, and has high stability and excellent p-AMPK activity, compared to existing adiponectin receptor peptides and has improved physical properties and activity, thus having the advantage of being suitable for drug formulation. Therefore, the peptoid derivative of the present invention can be used for the prevention or treatment of skin inflammatory diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, or the prevention or amelioration of aging, sensitive skin, wrinkles, or moisturization.

Abstract: Disclosed are a method and an apparatus for managing a user profile. A user profile management method performed by a server according to an example embodiment includes creating a plurality of profiles corresponding to a user account, receiving a view request for a profile of the other user account in a predetermined relationship with the user account from a user terminal logged in with the user account, providing a UI of a profile of the other user account including an interfacing object regarding the profile of the user account to the user account, receiving an input for selecting a profile to be displayed on the other user terminal logged in the other user account, among a plurality of profiles corresponding to the user account through the interfacing object, and matching the other user account with the selected profile.

Abstract: Disclosed are a method and an apparatus for managing a user profile. A user profile management method performed by a server according to an example embodiment includes creating a plurality of profiles corresponding to a user account, receiving a view request for a profile of the other user account in a predetermined relationship with the user account from a user terminal logged in with the user account, providing a UI of a profile of the other user account including an interfacing object regarding the profile of the user account to the user account, receiving an input for selecting a profile to be displayed on the other user terminal logged in the other user account, among a plurality of profiles corresponding to the user account through the interfacing object, and matching the other user account with the selected profile.

Abstract: Disclosed are a method and an apparatus for managing a user profile. A user profile management method performed by a server according to an example embodiment includes creating a plurality of profiles corresponding to a user account, receiving a view request for a profile of the other user account in a predetermined relationship with the user account from a user terminal logged in with the user account, providing a UI of a profile of the other user account including an interfacing object regarding the profile of the user account to the user account, receiving an input for selecting a profile to be displayed on the other user terminal logged in the other user account, among a plurality of profiles corresponding to the user account through the interfacing object, and matching the other user account with the selected profile.

Abstract: A display apparatus in which each unit pixel includes four sub-pixels is provided. The four sub-pixels of each unit pixel may sequentially receive a data line through single data line. Two sub-pixels disposed on a side of the data line may be connected to a reference voltage supply line by a reference connecting line intersecting the data line. Two sub-pixels disposed another side of the data line may be connected to the data line by a data connection line intersecting the reference voltage supply line. An intersection region of the reference connection line and the data line may have the same area as an intersection region of the data connection line and the reference voltage supply line. Thus, in the display apparatus, the variation in the charging rate due to the parasitic capacitance difference of the data connection line and the reference connection line may be reduced.

Abstract: A display apparatus in which each unit pixel includes four sub-pixels is provided. The four sub-pixels of each unit pixel may sequentially receive a data line through single data line. Two sub-pixels disposed on a side of the data line may be connected to a reference voltage supply line by a reference connecting line intersecting the data line. Two sub-pixels disposed another side of the data line may be connected to the data line by a data connection line intersecting the reference voltage supply line. An intersection region of the reference connection line and the data line may have the same area as an intersection region of the data connection line and the reference voltage supply line. Thus, in the display apparatus, the variation in the charging rate due to the parasitic capacitance difference of the data connection line and the reference connection line may be reduced.

Abstract: The present disclosure relates to a biomarker for predicting the sensitivity to a protein kinase inhibitor and a use thereof. The present disclosure provides a marker, a composition, and a kit for predicting the sensitivity to a protein kinase inhibitor, and a prediction method thereof. According to the present disclosure, the marker has an excellent effect of predicting the sensitivity to a protein kinase inhibitor, and thus the present disclosure can be useful for cancer treatment.

Abstract: Disclosed is a preparation method for a toner. Problems according to use of a surfactant can be solved and it is possible to prepare toner particles having a uniform distribution of particle size by using an alkali-soluble resin containing an acidic group.

Abstract: Disclosed are a hyaluronic acid derivative effective against atopic dermatitis, and a method for manufacturing same. The method for manufacturing the hyaluronic acid derivative of the present invention comprises: a first step of chlorinating ascorbic acid; a second step of producing a tetrabutylamonium hydroxide (TBA) salt of hyaluronic acid; and a third step of conjugating the ascorbic acid chlorinated in the first step and the TBA salt of hyaluronic acid produced in the second step. The hyaluronic acid derivative can effectively decrease the substances causing skin lesions, can contribute toward the remission of atopic disease, and is effective in skin renewal.

Abstract: A toner having a core-shell structure and a method of preparing the same. Since a shell includes a crosslinked resin, a toner preventing hot offsets and having excellent charge stability is prepared.