Patents by Inventor Hadi Alphonse

Hadi Alphonse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Viral Inactivation of Biological Fluids
    Publication number: 20110033554
    Abstract: The invention relates to a novel method of virally inactivating biological fluids by solvent/detergent treatment of the fluid, followed by oil extraction and filtration.
    Type: Application
    Filed: March 25, 2009
    Publication date: February 10, 2011
    Applicant: Research Foundation For Medical Devices
    Inventors: Thierry Burnouf, Magdy El-Ekiaby, Hadi Alphonse Goubran, Miryana Radosevich
  • PREPARATION OF VIRALLY INACTIVATED BIOLOGICAL FLUIDS HAVING HIGH ALPHA-2-ANTIPLASMIN ACTIVITY
    Publication number: 20100167378
    Abstract: The invention relates to the use of polyoxyethylene (4-5) p-t-octyl phenol (t-Oct-C6H4—(OCH2CH2)x0H, x=˜5) or polyoxyethylene (20) sorbitan monooleate in solvent/detergent viral inactivation of biological fluids for the preparation of a virally inactivated biological fluid having a high alpha 2-antiplasmin content.
    Type: Application
    Filed: February 14, 2008
    Publication date: July 1, 2010
    Applicant: RESEARCH FOUNDATION FOR MEDICAL DEVICES
    Inventors: Thierry Burnouf, Magdy El-Ekiaby, Hadi Alphonse Goubran, Miryana Radosevich
  • Viral reduction method for plasma using a leukocyte-reduction filter and two virus-reduction filters of decreasing pore diameters
    Patent number: 7592134
    Abstract: The present invention relates to a plasma product or a serum product with an extremely low risk of viral contamination and a method for producing the same. Before treating plasma or serum to be used as a raw material for producing a plasma product or a serum product using a virus removal membrane, leucocytes contaminating the blood are removed. Thus, a plasma product or a serum product with an extremely low risk of viral contamination can be efficiently produced while preventing clogging. Since clogging scarcely arises, it is possible to carry out efficient filtration without applying an elevated pressure as the filtration proceeds.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: September 22, 2009
    Assignee: Asahi Kasei Medical Co., Ltd.
    Inventors: Sakae Sato, Tetsuo Sato, Thierry Burnouf, Miryana Radosevich, Hadi Alphonse Goubran
  • Set of Disposable Bags for Viral Inactivation of Biological Fluids
    Publication number: 20070219524
    Abstract: The invention relates to a set system of disposable bags comprising at least one viral inactivation bag (1), comprising an inner compartment (4), an inlet facility (5) and an outlet facility (6), which are both connected to the inner compartment (4), the bag (1) being characterised in that the inner compartment (4) has an ovoid longitudinal section, and at least one funnel bag (9), and/or a column chromatography bag (15), the different bags being connectable with each other, and to the use of said set system of disposable bags for the viral inactivation of biological fluids with excellent protein recovery.
    Type: Application
    Filed: February 1, 2006
    Publication date: September 20, 2007
    Inventors: Thierry Burnouf, Magdy El-Ekiaby, Hadi Alphonse, Miryana Radosevich