Abstract: A needle protection assembly, adapted to protect a tip of a hypodermic needle, comprising a shield adapted, in a protected operative orientation of the needle protection assembly, to shield the tip of the hypodermic needle, a locking element including at least one slot, the slot including at least three surfaces corresponding to three operative orientations of the shield, at least one slot engaging element, functionally associated with the shield, the slot engaging element being disposed within the slot of the locking element and movable relative thereto, between the surfaces, so as to transition the shield between the three operative orientations, and at least one biasing element, adapted for axial biasing of the shield, wherein the three operative orientations include a storage operative orientation, an injection operative orientation, and a needle protection operative orientation.

Abstract: A method for monitoring blood vessels, the method including using a system for monitoring blood vessel functionality to look, listen and feel blood vessel functionality by imaging a patient's body to obtain blood vessel geometry, imaging a patient body to obtain a shape of a location of the patient's body using image analysis, and analyzing vibrations of the patient's body at a location of the patient's body which includes the blood vessels. A method for monitoring blood vessel functionality, the method including illuminating one or more blood vessels through a patient's skin, capturing at least one image of the blood vessels, analyzing the at least one image, and calculating a parameter associated with blood vessel functionality based upon the image analysis. Related apparatus and methods are also described.

Abstract: A method is described for performing suprachoroidal buckling in an eye of a subject. A sharp needle distal tip of a device is used to partially penetrate at a penetration point into a sclera of the eye, not completely through the sclera. An elongated tissue separator is moved distally within the needle lumen such that the separator distal tip moves distally to the sharp needle distal tip and penetrates into a choroid of the eye and forms a suprachoroidal passage in the choroid. The device is used to inject a fluid into the suprachoroidal passage. The fluid includes a therapeutic composition including viscous agents to achieve suprachoroidal buckling, including a short term buckling effect or a long term buckling effect.

Abstract: A method for displaying data on a patient's arm, the method including capturing an image of a patient's arm, analyzing the image, thereby obtaining information regarding a blood vessel in the patient's arm, displaying the information by projecting a light pattern on the patient's arm. A system for displaying data on a patient's arm, the system including a light source for illuminating a patient's arm, a sensor for capturing an image of the patient's arm, a computer for analyzing the image, thereby obtaining information regarding blood vessel in the patient's arm, a projector for displaying the information by projecting a light pattern on the patient's arm. Related apparatus and methods are also described.

Abstract: A method for monitoring blood vessels, the method including using a system for monitoring blood vessel functionality to look, listen and feel blood vessel functionality by imaging a patient's body to obtain blood vessel geometry, imaging a patient body to obtain a shape of a location of the patient's body using image analysis, and analyzing vibrations of the patient's body at a location of the patient's body which includes the blood vessels. A method for monitoring blood vessel functionality, the method including illuminating one or more blood vessels through a patient's skin, capturing at least one image of the blood vessels, analyzing the at least one image, and calculating a parameter associated with blood vessel functionality based upon the image analysis. Related apparatus and methods are also described.

Abstract: Provided is a device for injection into an interlayer of an organ of a subject. The device includes a needle having a size transitional portion terminating in a sharp needle distal tip. The device also includes an elongated tissue separator that is shiftable in the needle lumen. An actuator shifts the tissue separator in the needle lumen between a first position, in which the separator distal tip is fixedly positioned proximally to the needle distal tip, and a second position in which the separator distal tip is fixedly positioned a predetermined distance distally from the needle distal tip.

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: A kit includes an injector (1) including a substance syringe, which includes a plunger (3) that slides in a lumen of a barrel (4) which is coupled to a lumen of a needle (5), a fixation tool (10), and a coupling assembly (60) that includes a fixation-tool force transfer device (62) coupled to the fixation tool (10). The fixation-tool force transfer device (62) is coupled to the plunger (4) of the injector (1) such that actuation of the fixation-tool force transfer device (61) moves the plunger (4) of the injector (!).

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: A dual chamber injection system, comprising a guiding element arranged along a longitudinal axis and configured to at least partially contain a medicament container, the guiding element defines an inner surface and at least one protrusion extending radially inwardly therefrom; a plunger rod assembly, comprising a plunger outer portion arranged along the longitudinal axis and a plunger inner portion arranged concentrically within the plunger outer portion and having at least one guiding groove arranged on an outer surface of the plunger inner portion; the plunger outer portion is disposed externally relative to the guiding element; the plunger inner portion is at least partially received into the guiding element; and wherein the plunger rod assembly is displaceable relative to the guiding element and the displacement is guided by engagement of the at least one protrusion with the at least one guiding groove.

Abstract: A surgical fixation tool (10) includes at least one fixation member (12) which protrudes from a leg (16) of a proximal grasping portion (20). The at least one fixation member (12) includes a needle (28) with a sharp distal tip (29). The needle (28) protrudes distally from a support structure (30) that includes one or more sloped support surfaces (34, 36) that are sloped with respect to a needle shaft (27).

Abstract: A needle protection assembly, adapted to protect a tip of a hypodermic needle, comprising a shield adapted, in a protected operative orientation of the needle protection assembly, to shield the tip of the hypodermic needle, a locking element including at least one slot, the slot including at least three surfaces corresponding to three operative orientations of the shield, at least one slot engaging element, functionally associated with the shield, the slot engaging element being disposed within the slot of the locking element and movable relative thereto, between the surfaces, so as to transition the shield between the three operative orientations, and at least one biasing element, adapted for axial biasing of the shield, wherein the three operative orientations include a storage operative orientation, an injection operative orientation, and a needle protection operative orientation.

Abstract: A needle protection assembly, adapted to protect a tip of a hypodermic needle, comprising a shield adapted, in a protected operative orientation of the needle protection assembly, to shield the tip of the hypodermic needle, a locking element including at least one slot, the slot including at least three surfaces corresponding to three operative orientations of the shield, at least one slot engaging element, functionally associated with the shield, the slot engaging element being disposed within the slot of the locking element and movable relative thereto, between the surfaces, so as to transition the shield between the three operative orientations, and at least one biasing element, adapted for axial biasing of the shield, wherein the three operative orientations include a storage operative orientation, an injection operative orientation, and a needle protection operative orientation.

Abstract: A method for monitoring blood vessels, the method including using a system for monitoring blood vessel functionality to look, listen and feel blood vessel functionality by imaging a patient's body to obtain blood vessel geometry, imaging a patient body to obtain a shape of a location of the patient's body using image analysis, and analyzing vibrations of the patient's body at a location of the patient's body which includes the blood vessels. A method for monitoring blood vessel functionality, the method including illuminating one or more blood vessels through a patient's skin, capturing at least one image of the blood vessels, analyzing the at least one image, and calculating a parameter associated with blood vessel functionality based upon the image analysis. Related apparatus and methods are also described.

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: A manipulating device includes a hollow tube having a tube wall formed with distal cutouts that define at least one deformable member in the tube wall and proximal cutouts that define an actuator in the tube wall connected to the at least one deformable member. Movement of the actuator deforms the at least one deformable member from a first orientation to a second orientation.

Abstract: Provided is a device for injection into an interlayer of an organ of a subject. The device includes a needle having a size transitional portion terminating in a sharp needle distal tip. The device also includes an elongated tissue separator that is shiftable in the needle lumen. An actuator shifts the tissue separator in the needle lumen between a first position, in which the separator distal tip is fixedly positioned proximally to the needle distal tip, and a second position in which the separator distal tip is fixedly positioned a predetermined distance distally from the needle distal tip.

Abstract: A method for monitoring blood vessel functionality, the method including illuminating one or more blood vessels through a patient's skin, capturing at least one image of the blood vessels, analyzing the at least one image, and calculating a parameter associated with blood vessel functionality based upon the image analysis. A method for replacing a physical examination performed by medical staff for monitoring blood vessel functionality in dialysis patients, the method including producing at least one image of a patient organ instead of manually manipulating the patient's organ, analyzing the at least one image, and classifying the patient's status to be one of suitable for dialysis or at risk for dialysis. Related apparatus and methods are also described.

Abstract: Systems and devices for interfacing between a medicinal vial, a hypodermic needle, and an injection device such as a syringe, comprising a valve, functionally associated with said vial adaptor, said injection device port, and said needle, said valve having a first orientation wherein said injection device port is in fluid flow communication with said vial adaptor and a second orientation wherein said injection device port is in fluid flow communication with said hypodermic needle, wherein rotation of said injection device port between a first position and a second position thereof, drives transition of said valve from said first orientation to said second orientation.

Abstract: The invention provides a safe auto-needle device for injection, comprising: a main housing and a syringe-support receiving a disposable prefilled syringe terminating in a needle covered by a needle sheath (NS). The speed of depressing of the syringe plunger is manually controllable by a user. In a first embodiment, a locking mechanism is present, for preventing premature advancement of the needle. A second embodiment comprises an interlock, for preventing depressing of a plunger, prior to advancement of the syringe-support to a needle penetration location. Additional components include a drive mechanism; and a needle shield moveable between: a needle covered position; a partially exposed position, to a fully extended needle safe position. The invention also discloses a needle sheath (NS) remover.