Abstract: A mounting element (8) for releasably receiving a sensor (18) for transferring and/or receiving electrical currents and/or signals relating to a body of an organism, comprising a mounting element base (9) having a receiving space (17) for receiving the sensor (18), the receiving space (17) comprising a floor (19), a wall (16) disposed on the floor (19) and disposed on at least three sides, an opening (20) formed by at least one tab (21, 22), at least one clip closure (23, 24), and further comprising a cover (10) for the mounting element base (9), an at least three-sided wall being disposed on the inner side (11) thereof, the end face (30) thereof being implemented for contacting the end face (41) of the wall (16), wherein at least one counterpart (28, 29) to the at least one clip closure (23, 24) is disposed on the wall (27), and the mounting element base (9) and the cover (10) are connected to each other by a connecting element (13) such that the cover (10) is displaceable relative to the mounting element ba

Abstract: A mounting element (8) for releasably receiving a sensor (18) for transferring and/or receiving electrical currents and/or signals relating to a body of an organism, comprising a mounting element base (9) having a receiving space (17) for receiving the sensor (18), the receiving space (17) comprising a floor (19), a wall (16) disposed on the floor (19) and disposed on at least three sides, an opening (20) formed by at least one tab (21, 22), at least one clip closure (23, 24), and further comprising a cover (10) for the mounting element base (9), an at least three-sided wall being disposed on the inner side (11) thereof, the end face (30) thereof being implemented for contacting the end face (41) of the wall (16), wherein at least one counterpart (28, 29) to the at least one clip closure (23, 24) is disposed on the wall (27), and the mounting element base (9) and the cover (10) are connected to each other by a connecting element (13) such that the cover (10) is displaceable relative to the mounting element ba

Abstract: Cleaning system for cleaning at least one region of a medical device that can be brought in contact with a human or animal body. Means (14) for positioning the medical device in the cleaning system are present, such that the region that can be brought in contact with the human or animal body is positioned in a non-contact manner in the cleaning system.

Abstract: The invention relates to a method for treating a biological cell (1) including a cytoskeleton (3) enveloped by a cell membrane (2). The method includes the following steps: the biological cell (1) and a tool (10) are mutually oriented such that the tool (10) comes into contact with the biological cell (1); the tool (10) and the biological cell (1) are displaced in relation to each other; and a gap is formed in the molecular composite of the cell membrane (2) of the biological cell (1). During the displacement of the tool (10), the cytoskeleton (3) of the biological cell (1) has a state of equilibrium. The invention also relates to a cell manipulator for carrying out the inventive method.

Abstract: The invention lies in the technical field of cell biology and transplantation medicine. It concerns devices and methods for rapid and noninvasive analysis or checking of biological samples, especially for sterility control, for characterization of infectious particles and microorganisms contained in the biological sample and for characterization of tissue cells and transplants. The main areas of application of the invention are biotechnological production of pharmacological active ingredients and therapeutic agents as well as transplantation medicine.

Abstract: The invention lies in the technical field of cell biology and transplantation medicine. It concerns devices and methods for rapid and noninvasive analysis or checking of biological samples, especially for sterility control, for characterization of infectious particles and microorganisms contained in the biological sample and for characterization of tissue cells and transplants. The main areas of application of the invention are biotechnological production of pharmacological active ingredients and therapeutic agents as well as transplantation medicine.

Abstract: Disclosed is a device for detecting bioelectric signals from spheroids comprising a measuring chamber having a measuring chamber wall which encloses a volume, which is open at least at one side, is composed of an electrically non-conducting material, and has, in at least one measuring region, an inner cross section, which corresponds as far as possible to the largest cross section of a spheroid, comprising at least a number of electrodes which are disposed in a common plane inside said measuring chamber wall and each electrode has a freely accessible electrode surface which is oriented towards the measuring region, and comprising an impedance measuring arrangement which is connected to the electrodes. The device and the method can be used to test substances in 3D biological in-vitro (three-dimensional) cell aggregates.

Abstract: The invention relates to a method for treating a biological cell (1) including a cytoskeleton (3) enveloped by a cell membrane (2). The method includes the following steps: the biological cell (1) and a tool (10) are mutually oriented such that the tool (10) comes into contact with the biological cell (1); the tool (10) and the biological cell (1) are displaced in relation to each other; and a gap is formed in the molecular composite of the cell membrane (2) of the biological cell (1). During the displacement of the tool (10), the cytoskeleton (3) of the biological cell (1) has a state of equilibrium. The invention also relates to a cell manipulator for carrying out the inventive method.

Abstract: A cell transfer method is described, in which transfer of at least one biological cell (21) describing a natural cell locomotion between a carrier (80) and a probe (10) is provided, and whereby positioning the probe (10) and the carrier (80) relative to one another in a transfer arrangement is provided, in which transfer of the cell (21) takes place due to the natural cell locomotion. Probes and cell manipulators for transferring biological cells are also described.

Abstract: The present invention relates to a device and a method for characterizing spheroids. The to-be-characterized spheroid is introduced into a tube of an electrically insulating material and with an inner diameter which is smaller than the diameter of the to-be-characterized spheroid in such a manner that the latter is in mechanical contact over the entire circumference with the inner wall of the electrically insulated tube. Electrodes are disposed on both sides of the spheroid in the tube. By means of these electrodes, a current flow can be generated through the spheroid and the resulting drop in voltage at the spheroid can be measured. The invented arrangement and the corresponding method permits producing an impedance spectrum of spheroids with high sensitivity, thereby realizing rapid and nondestructive characterization of spheroids.

Abstract: A cell transfer method is described, in which transfer of at least one biological cell (21) describing a natural cell locomotion between a carrier (80) and a probe (10) is provided, and whereby positioning the probe (10) and the carrier (80) relative to one another in a transfer arrangement is provided, in which transfer of the cell (21) takes place due to the natural cell locomotion.

Abstract: Disclosed is a device for detecting bioelectric signals from spheroids comprising a measuring chamber having a measuring chamber wall which encloses a volume, which is open at least at one side, is composed of an electrically non-conducting material, and has, in at least one measuring region, an inner cross section, which corresponds as far as possible to the largest cross section of a spheroid, comprising at least a number of electrodes which are disposed in a common plane inside said measuring chamber wall and each electrode has a freely accessible electrode surface which is oriented towards the measuring region, and comprising an impedance measuring arrangement which is connected to the electrodes. The device and the method can be used to test substances in 3D biological in-vitro (three-dimensional) cell aggregates.