Abstract: The present application relates to the field of biomedicine, and relates to a combined pharmaceutical composition for treating biliary tract tumor, liver cancer, triple negative breast cancer or lung cancer. The combined pharmaceutical composition comprises an anti-PD-L1 antibody and anlotinib, and has good anti-biliary tract tumor, liver cancer, triple negative breast cancer or lung cancer activity.

Abstract: An apparatus configured to measure current includes a probe configured to connect to a device under test and touch probe circuitry connected to the probe. The touch probe circuitry is configured to detect, via the probe, a leakage or touch current of the device under test while the device under test is connected to a power source. The apparatus further includes analog to digital converter circuitry configured to receive the leakage or touch current from the touch probe circuitry. The analog to digital converter further outputs at least one digital value related the leakage or touch current. The apparatus further includes current monitor circuitry configured to detect differential current between power lines connected to the device under test. The analog to digital converter circuitry is further configured to receive the differential current from the current monitor circuitry and output at least one digital value related to the differential current.

Abstract: Provided is a novel screening system for a drug target antagonist based on cell life/death phenotype. Specifically, on the basis of a target protein and a conditional suicide protein FKBP 12 (F36V)-Caspase9, a screening system is designed for screening a target protein inhibitor or a degradation agent. The screening system is stable and efficient, the phenotype is obviously easy to observe, and the screening system can be used for high-throughput screening.

Abstract: A comprehensive two-dimensional gas chromatograph, comprising a sample injector, a primary dimension column, a two-position three-way valve, a secondary dimension column, a three-way tube, a heating oven and a detector, wherein an inlet end(s) of the sample injector is connected to a carrier gas line and as well to a sample line, and an outlet end thereof is connected to a first end of the primary dimension column, a second end of the primary dimension column is connected to a first branch of the three-way tube, a second branch of the T-union is connected to a first end of the secondary dimension column, a second end of the secondary dimension column is connected to an inlet of the detector, a third branch of the three-way tube is connected to a gas inlet of the two-position three-way valve, and a first gas outlet of the two-position three-way valve is connected to the carrier gas line.

Abstract: The present invention provides a quinoline derivative for treating triple-negative breast cancer and use thereof in preparing a pharmaceutical composition for treating a tumor.

Abstract: The present application relates to the field of biomedicine, and relates to a combined pharmaceutical composition for treating biliary tract tumor, liver cancer, triple negative breast cancer or lung cancer. The combined pharmaceutical composition comprises an anti-PD-L1 antibody and anlotinib, and has good anti-biliary tract tumor, liver cancer, triple negative breast cancer or lung cancer activity.

Abstract: A comprehensive two-dimensional gas chromatograph, comprising a sample injector, a primary dimension column, a two-position three-way valve, a secondary dimension column, a three-way tube, a heating oven and a detector, wherein an inlet end(s) of the sample injector is connected to a carrier gas line and as well to a sample line, and an outlet end thereof is connected to a first end of the primary dimension column, a second end of the primary dimension column is connected to a first branch of the three-way tube, a second branch of the T-union is connected to a first end of the secondary dimension column, a second end of the secondary dimension column is connected to an inlet of the detector, a third branch of the three-way tube is connected to a gas inlet of the two-position three-way valve, and a first gas outlet of the two-position three-way valve is connected to the carrier gas line.

Abstract: A Cardamine hupingshanensis selenium-enriched Chinese yellow rice wine and a production method are provided. The production method is performed as follows. Fresh C. hupingshanensis is selected, followed by preparing the C. hupingshanensis into a juice containing effective components of C. hupingshanensis, or C. hupingshanensis powder. Glutinous rice raw materials are soaked in clear water, followed by taking out and steaming to obtain steamed glutinous rice. The steamed glutinous rice is cooled and mixed with distillers' yeast for pre-fermentation, after a temperature of fermented material rising to a harrowing temperature, a pre-fermented product is obtained by harrowing regularly. A post-fermentation is performed, followed by performing a pressure filtration. A pressure filtrate is put aside for clarification, followed by filtering and sterilizing, then adding the juice. Alternatively, the C.

Abstract: A brewing process of a Chinese yellow rice wine rich in active ingredients of Stachys sieboldii Miq. and Allium cepa L. by preparing Stachys sieboldii Miq. and Allium cepa L. into a juice or a powder respectively; immersing raw glutinous rice in water for water absorption and expansion, steaming, placing in a fermentation tank for pre-fermentation, stirring with a rake regularly when a temperature of fermented materials rises to a certain temperature to obtain a pre-fermented product; post-fermenting with the pre-fermented product, press filtering, allowing a press filtrate to stand still for clarification, filtering, heat sterilizing, adding a juice containing active ingredients of the Stachys sieboldii Miq. and a juice containing active ingredients of the Allium cepa L. into every 1 L of the press filtrate to obtain a Chinese yellow rice wine rich in active ingredients of Stachys sieboldii Miq. and Allium cepa L.

Abstract: The present invention provides a quinoline derivative for treating triple-negative breast cancer and use thereof in preparing a pharmaceutical composition for treating a tumor.

Abstract: Provided in the present invention is a quinoline derivative for treating gastric cancer. 1-[[[4-(4-fluoro-2-methyl-1H-indol-5-yl)oxy-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropylamine or a pharmaceutically acceptable salt, a hydrate or a prodrug thereof as provided in the present application can effectively treat gastric cancer, and can stabilize or relieve the state of illness of a gastric cancer patient.

Abstract: The present invention relates to methods and apparatuses for providing selective network access, wherein a cell type indication is provided based on at least one of a preamble and a header portion of a broadcast signal. At the receiving end, it is checked based on at least one of the preamble and the header portion, whether broadcast signals are received from different first and second cell types. The first cell type is selected for network access, if both broadcast signals from the first and second cell types are received with sufficient strength.

Abstract: The present invention relates to methods and apparatuses for providing selective network access, wherein a cell type indication is provided based on at least one of a preamble and a header portion of a broadcast signal. At the receiving end, it is checked based on at least one of the preamble and the header portion, whether broadcast signals are received from different first and second cell types. The first cell type is selected for network access, if both broadcast signals from the first and second cell types are received with sufficient strength.

Abstract: Provided in the present invention is a quinoline derivative for treating gastric cancer. 1-[[[4-(4-fluoro-2-methyl-1H-indol-5-yl)oxy-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropylamine or a pharmaceutically acceptable salt, a hydrate or a prodrug thereof as provided in the present application can effectively treat gastric cancer, and can stabilize or relieve the state of illness of a gastric cancer patient.

Abstract: The invention is directed to a method of characterizing a mechanism of action of an agent (e.g., a chemotherapeutic agent, a genotoxic agent). The method comprises contacting a plurality of populations of cells with an agent to be assessed, wherein each population of cells have one gene of interest targeted by a small hairpin RNA (shRNA) and wherein said gene of interest regulates cell death and a plurality of genes that regulate cell death are targeted in the plurality of populations of cells. A responsiveness of each population of cells to the agent is determined, thereby obtaining an shRNA signature of the agent, so as to identify one or more genes that mediate a response to the agent, thereby characterizing the mechanism of action of the agent. The invention is also directed an article of manufacture for characterizing a mechanism of action of a chemotherapeutic or genotoxic agent.

Abstract: A base station handover method and system for a communication system are provided. The method includes: a serving base station triggering a bi-casting operation according to information reported by a user equipment, adding a communication context of a target base station into a Mobile Management Entity (MME), and the MME notifying a Serving GateWay (SGW) to store two communication routes; the SGW communicating with the serving base station and the target base station after the triggering of bi-casting is completed; and the serving base station interacting with the user equipment, and handing over the user equipment from the serving base station to the target base station. By means of the technical scheme according to the embodiments of the present document, the complexity of base station handover can be reduced, the efficiency of base station handover can be increased, and at the same time the practicability is enhanced.

Abstract: Embodiments of the present invention relate to the field of electronic products and provide a method, an apparatus, and a system for supplying power to an active noise reduction headset, which can resolve a problem that a power supply operation of the active noise reduction headset is highly complex. The method for supplying power to an active noise reduction headset includes: receiving a signal of first voltage transmitted by a terminal; processing the signal of the first voltage to obtain a signal of second voltage, where the second voltage is less than the first voltage, and the signal of the second voltage is transmitted to a noise reduction chip of the active noise reduction headset, so that the noise reduction chip of the active noise reduction headset obtains the signal of the second voltage to implement a noise reduction function.

Abstract: A test apparatus for testing of a stop mechanism on a saw includes a support arm movable relative to a blade of the saw from a first position to a second position. The test apparatus also includes a simulation member coupled to the support arm. In the first position, the first end of the simulation member is offset from a portion of the blade of the saw, and in the second position, the first end of the simulation member is adapted to be in contact with the portion of the blade of the saw. The test apparatus further includes circuitry operatively connected to the simulation member to replicate an electrical property of a human finger such that contact between the blade and the first end of the simulation member triggers the stop mechanism of the saw.

Abstract: A method of data-aided timing recovery for Ethernet systems is disclosed. A first device negotiates a pseudorandom number sequence with a second device and receives a data signal from the second device. The first device samples the received data signal to recover a first training sequence. The first device also generates a second training sequence based on the pseudorandom number sequence. The second training sequence is then synchronized with the first training sequence. The synchronized second training sequence is used to align a receive clock signal of the first device with the data signal received from the second device.

Abstract: A test apparatus for testing of a stop mechanism on a saw includes a support arm movable relative to a blade of the saw from a first position to a second position. The test apparatus also includes a simulation member coupled to the support arm. In the first position, the first end of the simulation member is offset from a portion of the blade of the saw, and in the second position, the first end of the simulation member is adapted to be in contact with the portion of the blade of the saw. The test apparatus further includes circuitry operatively connected to the simulation member to replicate an electrical property of a human finger such that contact between the blade and the first end of the simulation member triggers the stop mechanism of the saw.