Abstract: Proteins can be purified and concentrated from crude cell lysates using high-throughput, automated process control systems that use software application programs to instruct one or more processors, controllers, and actuators to control and/or monitor the operations of filtration, purification, and concentration modules in such systems. The high-throughput production of concentrated proteins can be enabled by filtering the lysates and using compressed, non-reactive gas to concentrate the purified proteins, rather than using more complex centrifugation techniques.

Abstract: An injection molding machine includes various devices for reducing injection cycle time. A molded article detection apparatus and method are disclosed. The detection system and method determines if an article, or a portion thereof, remains on a machine core pin after the article ejection cycle has occurred, and, if so, communicates this condition to both the machine controller and the take-out controller. This prevents the machine from starting a new cycle and damaging the injection mold. Also, by communicating the extraction status to both the take-out controller and machine controller, if no articles or portions remain, injection cycle time is reduced. Additionally, a variable vacuum pressure apparatus and method are described. The apparatus and method allows early removal of molded articles from the molds into a take-out plate while the parts are still warm.