Abstract: Provided are methods and devices for loss evaluation to automated driving. The method includes: taking classes or localizations of observations as tasks of an automated driving model; correcting loss of each of the observations based on real-world scenarios in driving practice. In the present disclosure, the evaluation of algorithms in automated driving can be set with true realistic value in real world scenario; and rectify the misalignment from using of generic evaluation methods to algorithms used in automated driving scenarios.

Abstract: YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.

Abstract: A method for fabricating a protonic ceramic energy device includes: coating an electrolyte layer on an anode layer; and densifying the electrolyte layer by a rapid laser reactive sintering (RLRS) process on the electrolyte layer and/or the anode layer to form a half-cell comprising a dense electrolyte and a porous anode.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A pH micro-probe, a temperature micro-probe, and an immuno-based micro-probe each include a shaft for transmuting an input light signal and a tip for inserting into a cell or other substance for measuring pH, temperature, and/or antigens. The pH micro-probe and the temperature micro-probe each include a luminescent material positioned on the tip of the micro-probe. The light signal excites the luminescent material so that the luminescent material emits a luminescent light signal. The luminescent light signal has a property value dependent on the pH or temperature being measured and reflects back through the shaft for being measured by a light signal measuring device. The immuno-based micro-probe includes a reflective material that has an effective refractive index dependent on the number of antigen-antibody bonds present on the reflective material.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.

Abstract: Devices, systems, and methods provide direct digitization and encoding of a parameter to be sensed or measured. Digitized readings are encoded into binary bits, which are acquired and handled by digital devices. An all-digital sensing device can be implemented in passive, active, or semi-passive forms, and in some embodiments includes a transducer, digitizer/encoder, reader, and transmitter. A transducer converts the parameter to be measured into a digitizable quantity, based on such as mechanical deformation, dielectric properties, or electromagnetic wave or acoustic-wave properties. A piezoelectric material transducer converts stress/pressure into resistance or voltage. A fiber-optic interferometer transducer converts pressure/temperature/PH into irradiation amplitude or wavelength shift in spectrum domain. Encoded binary or quasi-binary states are identified by a reader. Binary states have resolutions arranged according to a 2N format.

Abstract: Devices, systems, and methods provide direct digitization and encoding of a parameter to be sensed or measured. Digitized readings are encoded into binary bits, which are acquired and handled by digital devices. An all-digital sensing device can be implemented in passive, active, or semi-passive forms, and in some embodiments includes a transducer, digitizer/encoder, reader, and transmitter. A transducer converts the parameter to be measured into a digitizable quantity, based on such as mechanical deformation, dielectric properties, or electromagnetic wave or acoustic-wave properties. A piezoelectric material transducer converts stress/pressure into resistance or voltage. A fiber-optic interferometer transducer converts pressure/temperature/PH into irradiation amplitude or wavelength shift in spectrum domain. Encoded binary or quasi-binary states are identified by a reader. Binary states have resolutions arranged according to a 2N format.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A pH micro-probe, a temperature micro-probe, and an immuno-based micro-probe each include a shaft for transmuting an input light signal and a tip for inserting into a cell or other substance for measuring pH, temperature, and/or antigens. The pH micro-probe and the temperature micro-probe each include a luminescent material positioned on the tip of the micro-probe. The light signal excites the luminescent material so that the luminescent material emits a luminescent light signal. The luminescent light signal has a property value dependent on the pH or temperature being measured and reflects back through the shaft for being measured by a light signal measuring device. The immuno-based micro-probe includes a reflective material that has an effective refractive index dependent on the number of antigen-antibody bonds present on the reflective material.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: An optical carrier based microwave interferometry (OCMI) system for measuring a physical, chemical, or biological property broadly comprises an optical carrier signal source, a waveguide, a microwave envelope signal source, a microwave modulator, an optical interferometer, a detector, and an analyzer. An optical carrier signal is modulated with a microwave envelope signal and transmitted through an optical interferometer. The optical signal is interrogated in microwave domain to obtain interference patterns or absorption/emission spectra corresponding to the physical, chemical, or biological property being measured.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A device and method include a broadband light source in communication with a waveguide to provide a light signal for interrogating each of a plurality for sensors within the waveguide. An analyzer modulates the light signal with a microwave signal and demodulates and evaluates light signals reflected by the sensors. An amplitude and a phase of each reflected signal from each sensor is distinguished in the time domain and the modulated signal is reconstructed in the frequency domain.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A global manager computer generates management instructions for a particular managed server within an administrative domain according to a set of rules. A global manager computer identifies a traffic midpoint device through which the provider managed server provides a service to a user device. The global manager determines a relevant rule from the set of rules that is applicable to communication between the provider managed server and the user device and generates a backend rule that is applicable to communication between the provider managed server and the traffic midpoint device. The global managed generates a backend function-level instruction including a reference to an actor-set authorized to communicate with the provider managed server to use the service. The global manager sends the backend function-level instruction to the provider managed server to configure the provider managed server to enforce the backend rule on communication with the actor-set including the traffic midpoint device.

Abstract: A pH micro-probe, a temperature micro-probe, and an immuno-based micro-probe each include a shaft for transmitting an input light signal and a tip for inserting into a cell or other substance for measuring pH, temperature, and/or antigens. The pH micro-probe and the temperature micro-probe each include a luminescent material positioned on the tip of the micro-probe. The light signal excites the luminescent material so that the luminescent material emits a luminescent light signal. The luminescent light signal has a property value dependent on the pH or temperature being measured and reflects back through the shaft for being measured by a light signal measuring device. The immuno-based micro-probe includes a reflective material that has an effective refractive index dependent on the number of antigen-antibody bonds present on the reflective material.

Abstract: A microresonator structure comprises a waveguide and a microsphere. The waveguide is of elongated cylindrical shape and includes a first section of optical transmission material and a cavity section axially aligned with the first section. The cavity section includes a first cavity and a second cavity. The first cavity is adjacent to the first section and includes a first sidewall of optical transmission material with an inner surface that tapers inward to an apex positioned adjacent to the first section. The second cavity is positioned adjacent to the first cavity of hollow cylindrical shape and includes a circumferential second sidewall of optical transmission material that abuts the first sidewall. The microsphere has a spherical outer surface and is positioned within the cavity section such that the outer surface contacts a portion of the first sidewall and a portion of the second sidewall.