Patents by Inventor Haichao Zhang

Haichao Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12209244
    Abstract: The present disclosure provides an innovative method for improving the enzyme activity of an NMN biosynthetic enzyme Nampt, and relates to the technical field of genetic engineering. A mutant protein of the present disclosure is obtained by firstly analyzing a target protein Nampt using two softwares FoldX and DeepDDG, and then predicting multiple key sites influencing the enzyme functions and finally performing the semi-rational design of the enzyme. In the examples of the present disclosure, 10 mutant strains are constructed using the designed primers according to the principle of point mutation, and 8 of the mutants have higher activity than a wild-type strain, in which the NMN yield of the mutant Nampt-V365L is increased by 62%, and the NMN yields of the mutants Nampt-S248A, Nampt-N164L, Nampt-S382M, Nampt-A245T and Nampt-A208G are increased by 34%, 27%, 27%, 22% and 17% respectively.
    Type: Grant
    Filed: September 21, 2022
    Date of Patent: January 28, 2025
    Assignee: HOBOOMLIFE BIO-TECHNOLOGY (SHENZHEN) CO., LTD.
    Inventors: Liqing Zhao, Jiansheng Chen, Zhigang Duan, Haichao Zhang, Beijia Huang
  • Publication number: 20240365004
    Abstract: A method includes obtaining a first image frame captured using at least one imaging sensor. The method also includes determining that an optical code is contained within the first image frame and determining whether to automatically zoom onto the optical code. The method further includes, in response to determining to automatically zoom onto the optical code, identifying a zoom ratio to be applied. In addition, the method includes controlling the at least one imaging sensor to capture a second image frame that is zoomed onto the optical code using the zoom ratio. Determining whether to automatically zoom onto the optical code includes identifying a distance between the optical code and a nearest edge or a nearest corner in the first image frame and determining to automatically zoom onto the optical code based on the identified distance being greater than a threshold distance.
    Type: Application
    Filed: August 30, 2023
    Publication date: October 31, 2024
    Inventors: Zhicheng Tang, Haichao Zhang, Ji Liang, Sia Jeffry Saputra, Rathinamoorthy Mylsamy
  • Publication number: 20240362491
    Abstract: Disclosed in the present disclosure are a transfer reinforcement learning method and apparatus, multi-task reinforcement learning method and apparatus, relating to the field of intelligent control technology. The transfer reinforcement learning method includes determining operational instructions for instructing an agent to perform a first task; determining an inclusion relation between multiple second tasks and the first tasks based on the operational instructions; determining a shared parameter set corresponding to the multiple second tasks based on the inclusion relation between the multiple second tasks and the first task, wherein the shared parameter set includes a plurality of parameters shared by the multiple second tasks; and performing transfer reinforcement learning based on the shared parameter set and the first task to obtain model parameters of a target policy model corresponding to the first task.
    Type: Application
    Filed: April 28, 2023
    Publication date: October 31, 2024
    Applicant: Horizon Robotics Inc.
    Inventors: Haichao ZHANG, Lingfeng SUN, Wei XU
  • Patent number: 12021544
    Abstract: Disclosed are an analog-to-digital conversion circuit, an analog-to-digital conversion device, and a digital x-ray imaging system. The analog-to-digital conversion circuit includes a first reference voltage source, a second reference voltage source, a first analog-to-digital converter connected to the first reference voltage source, a second analog-to-digital converter connected to the second reference voltage source, a connecting circuit connected to the first analog-to-digital converter and the second analog-to-digital converter, respectively, and a current source having negative temperature coefficient configured to be connected to the first reference voltage source and the second reference voltage source, respectively.
    Type: Grant
    Filed: March 3, 2022
    Date of Patent: June 25, 2024
    Assignee: Shanghai United Imaging Microelectronics Technology Co., Ltd.
    Inventors: Rong Wu, Jieyou Zhao, Haichao Zhang
  • Patent number: 11958552
    Abstract: A bionic robot is provided, which includes a body; a plurality of sets of wheeled leg devices arranged at intervals in a front-rear direction, each comprising two wheeled leg devices arranged symmetrically in a left-right direction, each comprising a leg assembly and a travel wheel, and a power output shaft connected to the travel wheel; and a suspension device disposed in the body and connected to at least two sets from the plurality of sets of wheeled leg devices. The at least two sets of wheeled leg devices are located at the foremost end and the backmost end respectively. The suspension device comprises a plurality of drive assemblies, each connected to a corresponding leg assembly, which each comprise: an electric cylinder being configured to drive a telescopic rod to extend or retract; a damper connected between the body and the leg assembly; and an elastic member fitted over the damper.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: April 16, 2024
    Assignees: INNER MONGOLIA SU MENG TECHNOLOGY POWER EQUIPMENT CO., LTD., CHINA UNIVERSITY OF MINING & TECHNOLOGY, BEIJING
    Inventors: Jianwei Zhao, Hai Zhang, Zhikang Chi, Haichao Zhang, Chaoyi Liu, Xiaofei Ma
  • Publication number: 20240010605
    Abstract: Through an intermediate I (a compound having the structural formula as shown in the formula Ia and/or the formula Ib), or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a tautomer Ic of Ib, a bicyclopyrone intermediate II with a high yield can be prepared. Two compounds are docked first under the action of a base to produce an intermediate I, and then the intermediate I is subjected to intramolecular ring closure by an ammonium salt, which can increase the yield of the bicyclopyrone intermediate (II), reduce side reactions, and reduce problems that a reaction of raw materials is easily incomplete due to intramolecular ring closure directly through an ammonium salt. A one-pot method includes producing an intermediate I under the action of a base and then performing a ring-closure reaction to produce a bicyclopyrone intermediate (II) that reduces side reactions, and further increases the yield.
    Type: Application
    Filed: August 22, 2023
    Publication date: January 11, 2024
    Inventors: Zhiqing LI, Fenghua Gong, Haichao Zhang, Hongquan Zhang, Xiaoyang Qiu
  • Patent number: 11870710
    Abstract: In one embodiment, a method includes receiving, at a proxy application on a first computing device, a request from a first application on the first computing device to access a resource. The method further includes transmitting, from the proxy application on the first computing device, a modified version of the request to a proxy application on a second computing device and receiving, from the proxy application on the second computing device, a response comprising data from the requested resource, where the resource is on the second computing device. The method further includes transmitting, to the first application on the first computing device, a response satisfying the first application's request to access the resource.
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: January 9, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Haichao Zhang
  • Patent number: 11831124
    Abstract: The disclosure belongs to the technical field of photoelectric emission in semiconductors, and discloses an electro-absorption modulated laser chip and a fabrication method thereof, which can solve the problems of signal distortion caused by optical crosstalk between components in an existing electro-absorption modulated laser (EML) integrated with a semiconductor optical amplifier (SOA), and failure in longer-distance transmission.
    Type: Grant
    Filed: March 27, 2023
    Date of Patent: November 28, 2023
    Assignee: Yuanjie Semiconductor Technology Co., Ltd.
    Inventors: Mahui Li, Yenting Pan, Yao Mu, Yuchen Shi, Haichao Zhang
  • Publication number: 20230361526
    Abstract: The disclosure belongs to the technical field of photoelectric emission in semiconductors, and discloses an electro-absorption modulated laser chip and a fabrication method thereof, which can solve the problems of signal distortion caused by optical crosstalk between components in an existing electro-absorption modulated laser (EML) integrated with a semiconductor optical amplifier (SOA), and failure in longer-distance transmission.
    Type: Application
    Filed: March 27, 2023
    Publication date: November 9, 2023
    Applicant: Yuanjie Semiconductor Technology Co., Ltd.
    Inventors: Mahui LI, YENTING PAN, Yao MU, Yuchen SHI, Haichao ZHANG
  • Publication number: 20230347510
    Abstract: Disclosed in the present disclosure are a method for training a multi-task model through multi-task reinforcement learning, an apparatus, an electronic device and a non-transitory computer readable storage medium. A method for training a multi-task model through multi-task reinforcement learning, including: acquiring observation signals observed for an environment by an agent; receiving T instructions each for instructing the agent to perform one of T tasks, T being a preset positive integer greater than 1; and generating K base policy models by performing training through multi-task reinforcement learning over a neural network based on the observation signals and the T instructions, wherein the K base policy models are combinable for generating respective task policy models for the T tasks to obtain the multi-task model for achieving the T tasks.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Inventors: Haichao Zhang, Lingfeng Sun, Wei Xu
  • Patent number: 11795678
    Abstract: The present disclosure relates to the technical field of daily necessities, and provides a urinal, a squatting pan and a pedestal pan. The special urinal comprises a urinal, a sewage discharge port, a water inlet and a water outlet hole. The urinal has a first end adjacent to the sewage discharge port and a second end away from the sewage discharge port; the sewage discharge port is provided at the bottom of the urinal, the water outlet hole is communicated with the water inlet, the urinal is internally provided with a protruding portion that is used for being opposite to the anus of a user; one end of the protruding portion extends to the bottom of the urinal; and the water outlet hole is used for flushing the protruding portion. The present disclosure aims to solve the defect in the prior art that a female urinal cannot distinguish stool from urine.
    Type: Grant
    Filed: June 5, 2023
    Date of Patent: October 24, 2023
    Assignee: BAOMA YIXUAN ELECTRONIC COMMERCE (TIANJIN) CO., LTD.
    Inventor: Haichao Zhang
  • Publication number: 20230323650
    Abstract: The present disclosure relates to the technical field of daily necessities, and provides a urinal, a squatting pan and a pedestal pan. The special urinal comprises a urinal, a sewage discharge port, a water inlet and a water outlet hole. The urinal has a first end adjacent to the sewage discharge port and a second end away from the sewage discharge port; the sewage discharge port is provided at the bottom of the urinal, the water outlet hole is communicated with the water inlet, the urinal is internally provided with a protruding portion that is used for being opposite to the anus of a user; one end of the protruding portion extends to the bottom of the urinal; and the water outlet hole is used for flushing the protruding portion. The present disclosure aims to solve the defect in the prior art that a female urinal cannot distinguish stool from urine.
    Type: Application
    Filed: June 5, 2023
    Publication date: October 12, 2023
    Applicant: BAOMA YIXUAN ELECTRONIC COMMERCE (TIANJIN) CO., LTD.
    Inventor: Haichao ZHANG
  • Patent number: 11768932
    Abstract: Described herein are embodiments for fast training of adversarially robust models against adversarial attacks. Embodiments for model training by perturbing both the image and the label, which may be referred to as Bilateral Adversarial Training (BAT), are disclosed. To generate the adversarial label, one or more closed-form heuristic solutions are derived. One-step targeted attack is used with the target label being the most confusing class. It is shown in various experiments that random start and the most confusing target attack effectively prevent the label leaking and gradient masking problem. Coupled with the adversarial label part, embodiments of presented models significantly improve the state-of-the-art results. Experiments on one or more computationally challenging dataset also demonstrate the effectiveness of the presented BAT method embodiments.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: September 26, 2023
    Assignee: Baidu USA LLC
    Inventors: Jianyu Wang, Haichao Zhang
  • Publication number: 20230224259
    Abstract: In one embodiment, a method includes receiving, at a proxy application on a first computing device, a request from a first application on the first computing device to access a resource. The method further includes transmitting, from the proxy application on the first computing device, a modified version of the request to a proxy application on a second computing device and receiving, from the proxy application on the second computing device, a response comprising data from the requested resource, where the resource is on the second computing device. The method further includes transmitting, to the first application on the first computing device, a response satisfying the first application’s request to access the resource.
    Type: Application
    Filed: June 7, 2022
    Publication date: July 13, 2023
    Inventor: Haichao Zhang
  • Patent number: 11636332
    Abstract: Described herein are embodiments for a feature-scattering-based adversarial training approach for improving model robustness against adversarial attacks. Conventional adversarial training approaches leverage a supervised scheme, either targeted or non-targeted in generating attacks for training, which typically suffer from issues such as label leaking as noted in recent works. Embodiments of the disclosed approach generate adversarial images for training through feature scattering in the latent space, which is unsupervised in nature and avoids label leaking. More importantly, the presented approaches generate perturbed images in a collaborative fashion, taking the inter-sample relationships into consideration. Extensive experiments on different datasets compared with state-of-the-art approaches demonstrate the effectiveness of the presented embodiments.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: April 25, 2023
    Assignee: Baidu USA LLC
    Inventors: Haichao Zhang, Jianyu Wang
  • Patent number: 11598575
    Abstract: A side-open left-right-door arbitrary-opening structure of a refrigerator comprises four hinge shafts are fixedly connected at left and right sides of a refrigerator body in pairs respectively, left and right sides of upper and lower end faces of a refrigerator door are all provided with an opening neck, each hinge shaft is correspondingly placed in one opening neck, four hinge shaft stoppers are slidably arranged on the upper and lower end faces of the refrigerator door in pairs respectively, one spring is arranged between two hinge shaft stoppers in each pair, tail ends of the hinge shaft stoppers on the upper and lower end faces of the refrigerator door extend into the opening necks at the corresponding sides, and the hinge shafts at the corresponding sides are positioned in the opening necks.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: March 7, 2023
    Assignees: SKYWORTH ELECTRIC CO., LTD., Way Interglobal Network, LLC
    Inventors: Ping Wu, Haichao Zhang, Yanxi Chong, Wenwen Nie, Qinan Wu, Gary Xie
  • Publication number: 20230022968
    Abstract: The present disclosure provides an innovative method for improving the enzyme activity of an NMN biosynthetic enzyme Nampt, and relates to the technical field of genetic engineering. A mutant protein of the present disclosure is obtained by firstly analyzing a target protein Nampt using two softwares FoldX and DeepDDG, and then predicting multiple key sites influencing the enzyme functions and finally performing the semi-rational design of the enzyme. In the examples of the present disclosure, 10 mutant strains are constructed using the designed primers according to the principle of point mutation, and 8 of the mutants have higher activity than a wild-type strain, in which the NMN yield of the mutant Nampt-V365L is increased by 62%, and the NMN yields of the mutants Nampt-S248A, Nampt-N164L, Nampt-S382M, Nampt-A245T and Nampt-A208G are increased by 34%, 27%, 27%, 22% and 17% respectively.
    Type: Application
    Filed: September 21, 2022
    Publication date: January 26, 2023
    Inventors: Liqing ZHAO, Jiansheng Chen, Zhigang Duan, Haichao Zhang, Beijia Huang
  • Patent number: 11492627
    Abstract: The present disclosure provides an innovative method for improving the enzyme activity of an NMN biosynthetic enzyme Nampt, and relates to the technical field of genetic engineering. A mutant protein of the present disclosure is obtained by firstly analyzing a target protein Nampt using two softwares FoldX and DeepDDG, and then predicting multiple key sites influencing the enzyme functions and finally performing the semi-rational design of the enzyme. In the examples of the present disclosure, 10 mutant strains are constructed using the designed primers according to the principle of point mutation, and 8 of the mutants have higher activity than a wild-type strain, in which the NMN yield of the mutant Nampt-V365L is increased by 62%, and the NMN yields of the mutants Nampt-S248A, Nampt-N164L, Nampt-S382M, Nampt-A245T and Nampt-A208G are increased by 34%, 27%, 27%, 22% and 17% respectively.
    Type: Grant
    Filed: September 29, 2021
    Date of Patent: November 8, 2022
    Assignee: HOBOOMLIFE BIO-TECHNOLOGY (SHENZHEN) CO., LTD.
    Inventors: Liqing Zhao, Jiansheng Chen, Zhigang Duan, Haichao Zhang, Beijia Huang
  • Publication number: 20220348931
    Abstract: The present disclosure provides an innovative method for improving the enzyme activity of an NMN biosynthetic enzyme Nampt, and relates to the technical field of genetic engineering. A mutant protein of the present disclosure is obtained by firstly analyzing a target protein Nampt using two softwares FoldX and DeepDDG, and then predicting multiple key sites influencing the enzyme functions and finally performing the semi-rational design of the enzyme. In the examples of the present disclosure, 10 mutant strains are constructed using the designed primers according to the principle of point mutation, and 8 of the mutants have higher activity than a wild-type strain, in which the NMN yield of the mutant Nampt-V365L is increased by 62%, and the NMN yields of the mutants Nampt-S248A, Nampt-N164L, Nampt-S382M, Nampt-A245T and Nampt-A208G are increased by 34%, 27%, 27%, 22% and 17% respectively.
    Type: Application
    Filed: September 29, 2021
    Publication date: November 3, 2022
    Inventors: Liqing Zhao, Jiansheng Chen, Zhigang Duan, Haichao Zhang, Beijia Huang
  • Patent number: D1013130
    Type: Grant
    Filed: March 8, 2022
    Date of Patent: January 30, 2024
    Assignee: Baoma Yixuan E-Commerce (Tianjin) Co., Ltd.
    Inventor: Haichao Zhang