Patents by Inventor Haifeng Song
Haifeng Song has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220062409Abstract: Simian adenoviral vectors and RNA molecules, each encoding an immunogen of interest, can be sequentially administered to provide potent and long-lasting immunity.Type: ApplicationFiled: December 13, 2019Publication date: March 3, 2022Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Stefania CAPONE, Nicolas Frederic DELAHAYE, Giulietta MARUGGI, Haifeng SONG
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Patent number: 8962895Abstract: The present invention relates to a method for the production of ethylene glycol using a feedstock comprising an oxalate and a catalyst containing copper and/or a copper oxide, comprising contacting the feedstock with the catalyst in a reactor under the conditions of a temperature in the range from about 170 to about 270° C., a weight hourly space velocity of the oxalate in the range from about 0.2 to about 5 h?1, a molar ratio of hydrogen to the oxalate in the range from about 40:1 to about 200:1 and a reaction pressure in the range from about 1.5 to about 10 MPa, to produce an effluent containing ethylene glycol, in which the reactor is a tube-array reactor using partitioned heat exchange and adopting outer and inner tubes configured in a double-tube structure to facilitate the heat exchange of the catalyst.Type: GrantFiled: February 24, 2012Date of Patent: February 24, 2015Assignees: China Petroleum & Chemical Corporation, Shanghai Research Institute of Petrochemical Technology, SinopecInventors: Juntao Liu, Weimin Yang, Lei Li, Wanmin Wang, Linna Zhang, Haifeng Song
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Patent number: 8962319Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: GrantFiled: November 4, 2011Date of Patent: February 24, 2015Assignees: Sanofi Pasteur Vaxdesign Corp., Virginia Commonwealth UniversityInventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin, John G. Tew
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Publication number: 20140248640Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: ApplicationFiled: November 4, 2011Publication date: September 4, 2014Applicants: VIRGINIA COMMONWEALTH UNIVERSITY, SANOFI PASTEUR VAXDESIGN CORPORATIONInventors: William L. WARREN, Donald DRAKE, III, Janice MOSER, Inderpal SINGH, Haifeng SONG, Eric MISHKIN, John G. TEW
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Patent number: 8697371Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: GrantFiled: November 3, 2011Date of Patent: April 15, 2014Assignees: Sanofi Pasteur VaxDesign Corp., Virginia Commonwealth UniversityInventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin, John G. Tew
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Publication number: 20130338406Abstract: The present invention relates to a method for the production of ethylene glycol using a feedstock comprising an oxalate and a catalyst containing copper and/or a copper oxide, comprising contacting the feedstock with the catalyst in a reactor under the conditions of a temperature in the range from about 170 to about 270° C., a weight hourly space velocity of the oxalate in the range from about 0.2 to about 5 h?1, a molar ratio of hydrogen to the oxalate in the range from about 40:1 to about 200:1 and a reaction pressure in the range from about 1.5 to about 10 MPa, to produce an effluent containing ethylene glycol, in which the reactor is a tube-array reactor using partitioned heat exchange and adopting outer and inner tubes configured in a double-tube structure to facilitate the heat exchange of the catalyst.Type: ApplicationFiled: February 24, 2012Publication date: December 19, 2013Applicants: SHANGHAI RESEARCH INSTITUTE OF PETROCHEMICAL TECHNOLOGY, SINOPEC, CHINA PETROLEUM & CHEMICAL CORPORATIONInventors: Juntao Liu, Weimin Yang, Lei Li, Wanmin Wang, Linna Zhang, Haifeng Song
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Publication number: 20120052517Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: ApplicationFiled: November 3, 2011Publication date: March 1, 2012Applicants: VIRGINIA COMMONWEALTH UNIVERSITY, SANOFI PASTEUR VAXDESIGN CORPORATIONInventors: William L. WARREN, Donald DRAKE, III, Janice MOSER, Inderpal SINGH, Haifeng SONG, Eric MISHKIN, John G. TEW
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Patent number: 8080416Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: GrantFiled: February 17, 2010Date of Patent: December 20, 2011Assignee: Sanofi Pasteur Vaxdesign Corp.Inventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin
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Patent number: 8071373Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: GrantFiled: June 15, 2006Date of Patent: December 6, 2011Assignees: Sanofi Pasteur Vaxdesign Corp., Virginia Commonwealth UniversityInventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin, John G. Tew
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Publication number: 20110218114Abstract: A nucleotide triphosphate (NTP) participates in a phosphorylation reaction, wherein a phosphate group is transferred from the NTP to a substrate by a kinase. Provision in a kinase reaction of a NTP whose gamma phosphate is conjugated to an electroactive label results in the transfer of the gamma phosphate-electroactive label conjugate from the NTP to the substrate. The electroactive label is an organic moiety such as a quinone or a nitroheterocycle, or is a metallocene such as a ferrocene or a cobaltocene. Upon transfer of the gamma phosphate-electroactive label conjugate to an electrode-bound substrate by a kinase, the phosphorylation event is detected electrochemically by cyclic voltammetry. Phosphorylation can also be detected by mass spectrometry of a substrate carrying the electroactive label-conjugated gamma phosphate.Type: ApplicationFiled: September 26, 2008Publication date: September 8, 2011Inventors: Heinz-Bernhard Kraatz, Kagan Kerman, Haifeng Song
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Publication number: 20100287630Abstract: The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.Type: ApplicationFiled: March 17, 2010Publication date: November 11, 2010Applicant: VAXDESIGN CORP.Inventors: John G. TEW, Mohey Eldin M. EL SHIKH, Inderpal SINGH, Eric MISHKIN, Donald DRAKE, III, Haifeng SONG, William L. WARREN
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Patent number: 7785806Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: GrantFiled: November 8, 2006Date of Patent: August 31, 2010Assignee: Vaxdesign CorporationInventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin
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Publication number: 20100166763Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: ApplicationFiled: February 17, 2010Publication date: July 1, 2010Applicant: VAXDESIGN CORPORATIONInventors: William L. WARREN, Donald DRAKE, III, Janice MOSER, Inderpal SINGH, Haifeng SONG, Eric MISHKIN
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Patent number: 7709257Abstract: The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.Type: GrantFiled: June 27, 2007Date of Patent: May 4, 2010Assignees: Vax Design Corp., Virginia Commonwealth UniversityInventors: John G. Tew, Mohey Eldin M. El Shikh, Inderpal Singh, Eric Mishkin, Donald Drake, III, Haifeng Song, William L Warren
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Publication number: 20090117581Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: ApplicationFiled: November 8, 2006Publication date: May 7, 2009Inventors: William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin
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Publication number: 20080008653Abstract: The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.Type: ApplicationFiled: June 27, 2007Publication date: January 10, 2008Inventors: John Tew, Mohey Eldin El Shikh, Inderpal Singh, Eric Mishkin, Donald Drake, Haifeng Song, William Warren
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Publication number: 20070154956Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.Type: ApplicationFiled: June 15, 2006Publication date: July 5, 2007Inventors: William Warren, Donald Drake, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin