Abstract: This application provides novel bispecific antigen-binding antibodies, and antigen-binding fragments thereof, that bind to both HER2 and Trop-2. These bispecific anti-HER2/Trop-2 antibodies comprise a first antigen-binding domain that specifically binds human HER2 or Trop-2, and a second antigen-binding domain that specifically binds human Trop-2 or HER2. The bispecific antibodies have high binding affinity for HER2 and Trop-2, can be internalized by cells expressing HER2 and/or Trop-2. The bispecific antibody-drug conjugates (ADC) are capable of inhibiting the growth of tumors cells expressing HER2 and/or Trop-2 in vitro and in vivo. The bispecific antibodies can be used to diagnose, prognose, and treat HER2- and/or Trop-2-associated human diseases (e.g., cancer, infectious diseases, autoimmune diseases, asthma, transplant rejection, and inflammatory disorders).

Abstract: Methods and systems for training a model include distinguishing hidden states of a monitored system based on condition information. An encoder and decoder are generated for each respective hidden state using forward and backward autoencoder losses. A hybrid hidden state is determined for an input sequence based on the hidden states. The input sequence is reconstructed using the encoders and decoders and the hybrid hidden state. Parameters of the encoders and decoders are updated based on a reconstruction loss.

Abstract: A computer-implemented method for simulating vehicle data and improving driving scenario detection is provided.

Abstract: An insulation tape, a battery unit, a battery, a method and apparatus for preparing a battery unit, and a power consuming apparatus are provided. In some embodiments, the insulation tape includes a bottom surface coverage area, and a plurality of first side surface coverage areas and a plurality of second side surface coverage areas which are alternately arranged. Each of edges of the bottom surface coverage area is connected to one of the first side surface coverage areas or one of the second side surface coverage areas; each of the first side surface coverage areas includes a bottom covering portion and two side surface overlapping portions, a bottom edge of the bottom covering portion being connected to one of the edges of the bottom surface coverage area.

Abstract: According to example embodiments, there is provided a photoresist inspection method. The photoresist inspection method includes: providing a photoresist on a substrate; irradiating the photoresist with an electron beam and an excitation beam; detecting fluorescent light generated by the photoresist in response to the excitation beam; and evaluating the photoresist based on the fluorescent light.

Abstract: A multi-station wheel deburring device is disclosed, which consists of a lower lifting translation system, a first brush system, a second brush system, a synchronous clamping drive system and a third brush system, etc. The multi-station wheel deburring device can be used for removing burrs from the root of a wheel flange, a center hole, bolt holes and a back cavity, can automatically adjust the position of each brush according to the dimension and shape of a wheel, and at the same time, has the characteristics of high automation, high removal efficiency, advanced technology, strong universality and high safety and stability.

Abstract: The present disclosure discloses a cable and a cable processing method. The cable includes a wire core, a metal braid layer, a magnetic powder layer, a metal shield, an outer sheath and an elastic ring. The metal braid layer includes an inner braid portion and an everted braid portion which are mutually connected. The inner braid portion is wrapped around an outer side of the wire core, the magnetic powder layer is wrapped around an outer side of the inner braid portion, the metal shield is wrapped around an outer side of the magnetic powder layer, and the outer sheath is wrapped around an outer side of the metal shield. The elastic ring is sleeved outside the inner braid portion, the everted braid portion is wrapped around outer sides of the elastic ring and the outer sheath, and the elastic ring covers an end surface of the metal shield.

Abstract: The present application relates to a runout detection device, which includes a base plate, lateral plates, guide sleeves, springs and dial gauges, etc. During the operation, the sliding sleeve and the lateral dial gauge are moved along the sliding groove in the lateral formwork, so that the runout of right end of the work piece may be measured. The bottom plate of the lower end measuring device is placed above the base plate, the ball at the top end of the probe is always in contact with the lower end of the work piece under the action of the upper spring, the probe is pressed down when contacting a projection, and the L-shaped plate is rotated clockwise through the head nail, at this time, the runout of the lower end of the work piece may be known by the reading of the lower dial gauge.

Abstract: Present invention concerns optical processing of materials comprising complex phase behaviour, such as perovskites for stabilizing the optically active phase of thin films of materials with complex phase behaviour, such as perovskites.

Abstract: A gage for detecting the diameter of a bolt hole back socket consists of a go side cylinder, a first holder, a first digital depth gage, a first screw, a handle, a no-go side cylinder, a second screw, a second holder and a second digital depth gage. The gage can meet the detection requirement for the plane diameter of a bolt hole back socket of a wheel. An operator can use the gage to quickly detect whether the plane diameter of the bolt hole back socket is qualified, so that high-precision complete detection is realized. The gage converts depth detection into determination on whether the diameter is qualified.

Abstract: An automatic sand abrasion device includes a shell, an integrated framework, a sand falling mechanism, a sand transport mechanism, a sand falling channel, a sample working frame and a circuit control cabinet, where the device adopts the transport belt and the second speed reduction motor to realize transportation of sand, and realizes that the weighed sand falls into the bottom of the abrasion device through the first speed reduction motor and the automatic weighing machine. The whole process can be automatically operated while parameters such as the operation time and the weight of abrasion sand are set, so that the detection efficiency for the abrasion resistance can be improved, and the labor cost is greatly reduced. The device is firm in structure and stable and reliable in work and improves the accuracy and efficiency of an experiment.

Abstract: The present application relates to a runout detection device, which includes a base plate, lateral plates, guide sleeves, springs and dial gauges, etc. During the operation, the sliding sleeve and the lateral dial gauge are moved along the sliding groove in the lateral formwork, so that the runout of right end of the work piece may be measured. The bottom plate of the lower end measuring device is placed above the base plate, the ball at the top end of the probe is always in contact with the lower end of the work piece under the action of the upper spring, the probe is pressed down when contacting a projection, and the L-shaped plate is rotated clockwise through the head nail, at this time, the runout of the lower end of the work piece may be known by the reading of the lower dial gauge.

Abstract: A multi-station wheel deburring device is disclosed, which consists of a lower lifting translation system, a first brush system, a second brush system, a synchronous clamping drive system and a third brush system, etc. The multi-station wheel deburring device can be used for removing burrs from the root of a wheel flange, a center hole, bolt holes and a back cavity, can automatically adjust the position of each brush according to the dimension and shape of a wheel, and at the same time, has the characteristics of high automation, high removal efficiency, advanced technology, strong universality and high safety and stability.

Abstract: A gage for detecting the diameter of a bolt hole back socket consists of a go side cylinder, a first holder, a first digital depth gage, a first screw, a handle, a no-go side cylinder, a second screw, a second holder and a second digital depth gage. The gage can meet the detection requirement for the plane diameter of a bolt hole back socket of a wheel. An operator can use the gage to quickly detect whether the plane diameter of the bolt hole back socket is qualified, so that high-precision complete detection is realized. The gage converts depth detection into determination on whether the diameter is qualified.