Patents by Inventor Haikuo Ma

Haikuo Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl compounds as inhibitors of programmed necrosis pathway, composition and method using the same
    Publication number: 20230121233
    Abstract: The present disclosure provides heteroaryl compounds of Formula I, processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the programmed necrosis pathway.
    Type: Application
    Filed: January 4, 2021
    Publication date: April 20, 2023
    Inventors: Xiaohu Zhang, Haikuo MA, Sudan HE
  • Heteroaryl compounds as CXCR4 inhibitors, composition and method using the same
    Patent number: 11396501
    Abstract: The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the CXCR4 pathway.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: July 26, 2022
    Assignee: CGENETECH (SUZHOU, CHINA) CO., LTD.
    Inventors: Xiaohu Zhang, Jiyue Zheng, Haikuo Ma
  • Heteroaryl compounds as inhibitors of necrosis, composition and method using the same
    Patent number: 11339177
    Abstract: The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis.
    Type: Grant
    Filed: June 23, 2018
    Date of Patent: May 24, 2022
    Assignee: Accro Bioscience (HK) Limited
    Inventors: Xiaohu Zhang, Haikuo Ma, Jiyue Zheng, Sudan He
  • HETEROARYL COMPOUNDS AS NECROSIS INHIBITORS, COMPOSITION AND METHOD USING THE SAME
    Publication number: 20220112188
    Abstract: The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis.
    Type: Application
    Filed: January 11, 2020
    Publication date: April 14, 2022
    Inventors: Xiaohu Zhang, Sudan He, Haikuo MA
  • HETEROARYL COMPOUNDS AS INHIBITORS OF NECROSIS, COMPOSITION AND METHOD USING THE SAME
    Publication number: 20210155635
    Abstract: The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis.
    Type: Application
    Filed: June 23, 2018
    Publication date: May 27, 2021
    Inventors: Xiaohu Zhang, Haikuo Ma, Jiyue Zheng, Sudan He
  • Heteroaryl compounds as inhibitors of necrosis, composition and application thereof
    Patent number: 10815226
    Abstract: The present disclosure provides heteroaryl compounds of formulas I, Ia and Ib, processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis.
    Type: Grant
    Filed: July 15, 2017
    Date of Patent: October 27, 2020
    Assignee: ACCRO BIOSCIENCE INC.
    Inventors: Xiaohu Zhang, Haikuo Ma, Jiyue Zheng, Sudan He
  • HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME
    Publication number: 20200239439
    Abstract: The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the CXCR4 pathway.
    Type: Application
    Filed: September 24, 2018
    Publication date: July 30, 2020
    Inventors: Xiaohu Zhang, Jiyue Zheng, Haikuo Ma
  • HETEROARYL COMPOUNDS AS INHIBITORS OF NECROSIS, COMPOSITION AND APPLICATION THEREOF
    Publication number: 20190284180
    Abstract: The present disclosure provides heteroaryl compounds of formulas I, Ia and Ib, processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis.
    Type: Application
    Filed: July 15, 2017
    Publication date: September 19, 2019
    Inventors: Xiaohu Zhang, Haikuo Ma, Jiyue Zheng, Sudan He