Abstract: Structures and methods operable to detect radiation are described. The structure includes a dual-layer detector imaging device that permits one-shot of x-rays for dual-energy imaging. In one embodiment, a front layer of the detector includes a photon counting detector and aback layer of the detector includes an an x-ray radiation source for absorbing x-ray radiation to separate radiation into low energy and high energy components for incidence upon an imaging object. In an embodiment, the imaging object includes a contrast agent material having a characteristic K-edge atomic energy band level, and the separation filter absorbing the X-ray radiation is near the K-edge atomic energy band level.

Abstract: Provided herein are methods and systems for use in identifying a subject with inflammatory bowel disease based on certain criteria, including genetics or serological markers measured in a sample obtained from the subject. Also provided are methods and systems for treatment of the inflammatory bowel disease in the subject. The systems described herein may include polygenic risk score (PRS), which is useful for determining the relative risk of the subject as compared with a reference population.

Abstract: Disclosed is a diagnostic apparatus for a chronic obstructive pulmonary disease (COPD) based on prior knowledge CT subregion radiomics, belonging to the field of medical imaging. The diagnostic apparatus comprises: a subregion partitioning module based on prior knowledge configured for partitioning a CT lung image of a patient into three subregions based on the CT values of the interior of the lung, wherein the CT value of the interior of the lung of a subregion 1 is in the range of (?1024, ?950), the CT value of the interior of the lung of a subregion 2 is in the range of (?190, 110), and the CT value of the interior of the lung of a subregion 3 is in the range of (?950, ?190); a feature extraction module configured for extracting the radiomics features of the three subregions, respectively, and obtaining the LAA-950I features.

Abstract: The present disclosure provides a data processing method, including: receiving an expiration redemption file sent by a channel side and a mandatory redemption file sent by a third party system; when a verification of the expiration redemption file succeeds and the expiration redemption file is a closed one, judging whether redemption data contained in the expiration redemption file is identical with pre-stored purchase data; when the redemption data is identical with the pre-stored purchase data, and the mandatory redemption file requires full redemption on expiration, matching the expiration redemption file with the mandatory redemption file; and when the expiration redemption file is identical with the mandatory redemption file, generating a result confirmation file, informing the third party system, and sending the result confirmation file to the channel side.

Abstract: A novel set of methods for gene-based tests of association are provided. By gathering multiple independent effects into a single test, GWiS has greater power than conventional tests to identify genes with multiple causal variants. GWiS also retains power for low-frequency minor alleles that are increasingly important for personal genetics, a feature not shared by other multi-SNP tests. The methods of the present invention can be combined with conventional computing platforms to provide a new analytical tool for analyzing genes which are linked to multiple traits.