Abstract: A multi-module matrix control system dynamically manages the operation of electrolyzers across modules to optimize power allocation and maximize efficiency. Each module operates as an independent unit with multiple electrolyzers and corresponding power sources, utilizing linear and nonlinear algorithms for load distribution. The system includes innovative rotation strategies to balance wear and ensure longevity, fault prediction for proactive maintenance, and real-time adjustments to adapt to power input fluctuations. With three operational modes—Peak Performance, Dynamic Equilibrium, and Energy Conservation—the system seamlessly transitions between states based on power availability. This control approach enhances hydrogen production scalability, minimizes energy consumption, and ensures stable, efficient operation under varying conditions, making it ideal for applications ranging from megawatt to gigawatt-scale systems.

Abstract: A micro actuator for inner ear injection and sampling surgery is provided. The microneedle puncture mechanism module is embedded in the driving and sensing module. The driving and sensing module is installed on the high-precision linear driving module. The end-effector mechanism module is installed in the front of the driving and sensing module. The microneedle puncture mechanism module passes through the end operating mechanism module and extends. An endoscope camera module located in the end-effector mechanism module provides real-time images of a surgical process. A tension sensor in the driving and sensing module monitors tension changes of steel wires in real time to ensure safe interaction with the intra-ear environment.

Abstract: The disclosure relates to the technical field of electrolytic cells, in particular to a lightweight electrolyzer with a plug-in module comprising two end plates. An electrolysis chamber is arranged between the end plates, the electrolysis chamber includes an anode plate and a cathode plate, and two tie rods run through the two end plates, respectively, the electrolysis chamber is engaged with a chamber fixing frame engaged with a first splint and a second splint, both the outer sides of the first splint and the second splint are connected with fixing blocks and provided with grooves. The outside of the bottom of one of the end plates is fixedly connected with a slide rail, so that the fixing frame of the cell, the first splint, the second splint, and the guidance of the slide rail can be used to make the installation and disassembly more flexible.

Abstract: The present disclosure relates to an siRNA for inhibiting the expression of an angiopoietin-like protein 3 (ANGPTL3) gene, an siRNA conjugate, and a pharmaceutical composition thereof, and a method for reducing the expression of the ANGPTL3 gene by using the siRNA, the siRNA conjugate, and the pharmaceutical composition thereof. The siRNA, the siRNA conjugate, and the pharmaceutical composition thereof of the present disclosure can be used for treating and/or preventing an ANGPTL3 gene-mediated disease or disorder.

Abstract: The present invention discloses a class of compounds for gout, which is a compound as represented by general formula (I) or a pharmaceutically acceptable salt thereof, can reduce the serum uric acid level in a rat model of hyperuricemia, and has potential application value in aspects such as an anti-gout medicament and an anti-hyperuricemia medicament.

Abstract: The invention discloses a class of compounds for reducing uric acid, which are compounds represented by formula (I) or their pharmaceutically acceptable salts. The compounds can significantly reduce the serum uric acid level in the rat model of hyperuricemia, and have potential application value in aspects such as anti-gout medicaments and anti-hyperuricemia medicaments.

Abstract: It belongs to the field of medicinal chemistry, in particular discloses anti-inflammatory and analgesic compounds and use thereof, the compounds of the present invention are compounds, isomers or pharmaceutically acceptable salts as shown in formula (I) or formula (II); the compounds have significant curative effect on gouty arthritis in rats, and have excellent anti-inflammatory factor effect; therefore, the compounds have potential application prospects in anti-inflammatory and analgesic drugs, especially in anti-acute gouty arthritis drugs, anti-rheumatoid arthritis drugs, drugs to reduce inflammatory factors, drugs to treat inflammatory storm or coronavirus pneumonia.

Abstract: The present disclosure provides a method for extracting lithium using a resin adsorbent to pretreat low-grade deep brine, which relates to the technical field of lithium extraction from brine. In the present disclosure, resin adsorbent is used to perform adsorption pretreatment on the concentrated brine, which can adsorb organic impurities in the concentrated brine without adsorbing lithium ions, so that the concentration of lithium ions is almost unchanged compared with the feed material, with the subsequent manganese-based lithium adsorbent, the adsorption rate of lithium can be increased by 41%; At the same time, pretreating the concentrated brine using resin adsorbents has shorter steps, less materials, and does not produce a large amount of low-value product gypsum, which makes the lithium extraction process simpler and easier to operate, and reduces production costs.

Abstract: Provided are a new compound as represented by formula (I) having a dual antagonistic effect of an angiotensin II receptor and an endothelin receptor, and the use thereof in the preparation of a drug.

Abstract: The disclosure relates to the technical field of electrolytic cells, in particular to a lightweight electrolyzer with a plug-in module comprising two end plates. An electrolysis chamber is arranged between the end plates, the electrolysis chamber includes an anode plate and a cathode plate, and two tie rods run through the two end plates, respectively, the electrolysis chamber is engaged with a chamber fixing frame engaged with a first splint and a second splint, both the outer sides of the first splint and the second splint are connected with fixing blocks and provided with grooves. The outside of the bottom of one of the end plates is fixedly connected with a slide rail, so that the fixing frame of the cell, the first splint, the second splint, and the guidance of the slide rail can be used to make the installation and disassembly more flexible.

Abstract: A portable hydrogen electrolyzer integrated with water purifier indicating lifetime percentage of purification materials includes an electrolysis cell, a purification chamber, and an alterable color drying tower. A purification chamber ensures that the device can use regular water, instead of deionized water, for hydrogen production. Various configurations have been contemplated using fewer parts than other devices to decrease the risk of hydrogen leakage and improve the user experience.

Abstract: The invention relates to water-electrolysis hydrogen production technology, in particular to electrolyte supply structure for providing uniform fluid flow for large alkaline hydrogen electrolyzers. The electrolyte supply structure includes a bipolar electrode frame that has an electrolyzer cell inside, an outlet located at the top, and three inlets (a first inlet, a second inlet, and a third inlet) located at the left, middle, and right of the bottom, wherein the third inlet having a barrier plate located at the left inside. This invention, by setting the three inlets replacing the original two inlets and adjusting the inlets' width, quantities, and inlets' angles, effectively increases the uniformity of fluid flow inside the cell, improves performance, and has no influence on mechanical processing and cost.

Abstract: The present disclosure provides a method for extracting lithium using a resin adsorbent to pretreat low-grade deep brine, which relates to the technical field of lithium extraction from brine. In the present disclosure, resin adsorbent is used to perform adsorption pretreatment on the concentrated brine, which can adsorb organic impurities in the concentrated brine without adsorbing lithium ions, so that the concentration of lithium ions is almost unchanged compared with the feed material, with the subsequent manganese-based lithium adsorbent, the adsorption rate of lithium can be increased by 41%; At the same time, pretreating the concentrated brine using resin adsorbents has shorter steps, less materials, and does not produce a large amount of low-value product gypsum, which makes the lithium extraction process simpler and easier to operate, and reduces production costs.

Abstract: There are provided bivalent compounds and conjugates thereof, the conjugates comprising a bivalent compound, a targeting moiety, and a bioactive agent, as well as pharmaceutical compositions and methods of use of the conjugate for the treatment, inhibition, or prevention of diseases and disorders which are therapeutic targets of the bioactive agent.

Abstract: The invention discloses a self-derivative iron-containing nickel anode for alkaline water electrolysis and its preparation method. The anode comprises a nickel substrate and catalytic material layer. The catalytic layer is disposed on and integrated with the surface of the nickel substrate. The catalytic layer contains nickel oxide with iron components. The nickel oxide results from the reaction of the surface layer of the nickel substrate with an oxidant-rich alkaline solution and forms a nanosheet array layer. A nickel-oxidation state containing the iron component is formed by electrochemically induced iron-ion corrosion of the nickel-oxidation state. The invention can effectively reduce the potential difference between the anode and cathode of an electrolysis cell, thereby significantly reduces energy consumption and improves the efficiency of water electrolysis.

Abstract: The invention provides, among other things, a method for preparing a sintered nickel alkaline water electrolysis electrode for electrolytic hydrogen production. This method utilizes sintering furnace, ball-millings the mixture of nickel carbonate and selected nickel powder to obtain the raw material, adds polyvinyl alcohol to get the die under cold-pressing effect, sintering to make porous sintered nickel. In some embodiments, the surface of a nickel mesh used for the electrode is larger than the surface of the nickel mesh usually used in conventional hydrogen generation equipment and exhibits high-level catalytical activity and stability of hydrogen evolution. The proposed method is simple, easy to operate and has low production cost, which is suitable for electrolytic reactions under high current density conditions.

Abstract: The invention discloses a water electrolysis hydrogen production plant with a pumpless water supply system. The plant includes a water treatment system, a water tank, a water electrolysis device, and a controller. The water treatment system, water tank and water electrolysis device are sequentially connected together via pipelines and associated valves. Compressed gas is connected, via a pipeline, to the water tank, and serves to drive water from the water tank into the water electrolysis device. A process flow for the method of operating the pumpless water supply system in a water electrolysis hydrogen production plant is also disclosed.