Abstract: An anti-angiogenic composition is disclosed. The anti-angiogenic composition includes a multi-tyrosine kinase inhibitor having a chemical structure: where the tyrosine kinase inhibitor has a crystalline structure having a single crystal polymorph. The anti-angiogenic composition including the tyrosine kinase inhibitor, as characterized by powder x-ray diffraction, has diffraction peaks at 2? of 11.37 150 18.04 242 288 and 24.72. The tyrosine kinase inhibitor may have a particle size of from about 50 to about 300 microns. The tyrosine kinase inhibitor is injectable. The tyrosine kinase inhibitor has an anti-angiogenic efficacy as indicated by a reduction in endothelial cell marker cd31, vascular endothelial-cadherin (VE-CDH), smooth muscle pericyte marker alpha smooth muscle actin (ASMACT), or a combination thereof, as compared to a control composition.

Abstract: A control program is automatically generated to allow a shorter overall operation time of an automated manufacturing machine. An action chart includes subperiods assigned with element actions of actuators to describe the operation of the automated manufacturing machine. Program elements for the element actions are combined in an order of the subperiods to generate the control program. The action chart includes a parallel processing portion including subperiods and their parallel subperiods. Each parallel subperiod in the parallel processing portion is assigned with an element action of a predetermined selected actuator. Each subperiod in the parallel processing portion is assigned with an element action of another actuator. In the parallel processing portion, the control program is generated by combining, in an order of the parallel subperiods, the program elements for the parallel subperiods and combining, in an order of the subperiods, the program elements for the subperiods.

Abstract: A control program is automatically created using an action chart that is easy to create for an automated manufacturing machine with a complex operation. A subchart is pre-created for a set of consecutive subperiods of multiple subperiods included in an action chart. The action chart includes a subchart representation in a subperiod for identifying the subchart to represent the set of consecutive subperiods corresponding to the subchart. The action chart and the subchart are read together. Program elements for element actions in the subperiods on the action chart are combined together. For the subperiod with the subchart representation on the action chart, program elements for element actions assigned to the consecutive subperiods on the subchart are combined together in an order of the consecutive subperiods on the subchart. The control program is thus generated.

Abstract: A special suspension-type tracked underwater robot adaptable to ultra-soft geological conditions comprises traveling mechanisms, wherein the traveling mechanisms are track-mud sled structures, the mud sled structures are fixedly arranged on two sides of each track, and the bottoms of the mud sled structures are higher than the bottoms of the tracks and are provided with arched plate heads; the arched plate heads are provided with plate water-jet devices capable of spraying water forwards; and in the traveling process of the traveling mechanisms, and the arched plate heads press water downwards to form a water film at the bottoms of the mud sled structures together with the water sprayed by the plate water-jet devices, so that the traveling mud resistance is reduced, and the robot can stably advance under ultra-soft geological conditions.

Abstract: A stored control program includes subperiods into which an operation period from a start to an end of an operation of an automated manufacturing machine is divided. Each subperiod is assigned with an actuator to act and action information about the actuator. The subperiods are sequentially selected one by one as a control target, and feedback control is performed on an action of the actuator assigned to the selected subperiod. This reduces the number of actuators controlled at the same time for controlling the operation of an automated manufacturing machine including many actuators. The control program can thus be executed promptly with an operation control apparatus having ordinary processing capability.

Abstract: A special suspension-type tracked underwater robot adaptable to ultra-soft geological conditions comprises traveling mechanisms, wherein the traveling mechanisms are track-mud sled structures, the mud sled structures are fixedly arranged on two sides of each track, and the bottoms of the mud sled structures are higher than the bottoms of the tracks and are provided with arched plate heads; the arched plate heads are provided with plate water-jet devices capable of spraying water forwards; and in the traveling process of the traveling mechanisms, and the arched plate heads press water downwards to form a water film at the bottoms of the mud sled structures together with the water sprayed by the plate water-jet devices, so that the traveling mud resistance is reduced, and the robot can stably advance under ultra-soft geological conditions.

Abstract: A piece of submarine mining equipment comprises an equipment body, a plurality of adaptive submarine mining collectors and respective mineral delivery pipes. The equipment body and the adaptive submarine mining collectors are connected through the mineral delivery pipes. The lengths, stretching out of the equipment body, of the mineral delivery pipes can be adjusted under control. The adaptive submarine mining collectors are provided with tracked traveling mechanisms and can autonomously travel under control. An underwater detector is used for detecting the submarine topography and mineral distribution in the vicinity of an operation area, and the traveling path of the submarine mining collectors and a mineral storage vehicle is reasonably planned according to detected information. The multiple adaptive submarine mining collectors simultaneously and independently work and are made light and small, thus reducing damage of mining operations to the submarine ecological environment.

Abstract: A piece of submarine mining equipment comprises an equipment body, a plurality of adaptive submarine mining collectors and respective mineral delivery pipes. The equipment body and the adaptive submarine mining collectors are connected through the mineral delivery pipes. The lengths, stretching out of the equipment body, of the mineral delivery pipes can be adjusted under control. The adaptive submarine mining collectors are provided with tracked traveling mechanisms and can autonomously travel under control. An underwater detector is used for detecting the submarine topography and mineral distribution in the vicinity of an operation area, and the traveling path of the submarine mining collectors and a mineral storage vehicle is reasonably planned according to detected information. The multiple adaptive submarine mining collectors simultaneously and independently work and are made light and small, thus reducing damage of mining operations to the submarine ecological environment.