Abstract: Disclosed are a method for preparing 4-nitro-2-(trifluoromethyl) acetophenone and application thereof.

Abstract: A method for preparing 2-amino-5-chloro-N,3-dimethylbenzamide, including: subjecting o-toluidine to acylation reaction with an acylation agent to obtain o-methylacetanilide; subjecting the o-methylacetanilide to chlorination reaction with a chlorination agent to obtain 4-chloro-2-methylacetanilide; subjecting the 4-chloro-2-methylacetanilide to oximation reaction with an oximation agent to obtain 4-chloro-2-(hydroxyimino)-N-(2-methylphenyl) acetamide; subjecting the 4-chloro-2-(hydroxyimino)-N-(2-methylphenyl) acetamide to cyclization reaction with sulfuric acid to obtain 5-chloro-7-methylisatin; subjecting the 5-chloro-7-methylisatin to oxidation reaction with an oxidation agent to obtain 5-chloro-7-methylisatoic anhydride; and subjecting the 5-chloro-7-methylisatoic anhydride to ammonolysis reaction with monomethylamine to obtain the 2-amino-5-chloro-N,3-dimethylbenzamide

Abstract: The application provides a high-purity thermostable crystal form of a substituted 3-isoxazolidinone compound, a preparation method therefor and an application thereof. The High-purity thermostable crystal form is prepared by a particular method of the present technology and is determined by single-crystal X-ray diffraction as an orthorhombic crystal, featuring a space group of P212121 and lattice parameters of a=9.2301(2) ?, b=11.0751(3) ?, c=12.7554(3) A, ?=90°, ?=90°, and ?=90°. The orthorhombic crystal can be conveniently applied in preparation of agrochemical formulations, such as a suspension concentrate and a water dispersible granule, and the new formulations prepared have a better herbicidal activity and crop safety.

Abstract: The present disclosure provides a herbicide composition and a preparation method and an application method thereof, and relates to the technical field of herbicides. The herbicide composition includes pinoxaden and a cyclic lactone compound. The cyclic lactone compound is five-membered cyclic lactone and/or six-membered cyclic lactone. The herbicide composition solves the technical problems of poor chemical stability and precipitation due to crystallization at low temperature of existing pinoxaden emulsifiable concentrate formulations. In the herbicide composition, the cyclic lactone compound is used in combination with the pinoxaden, such that not only the solubility of the pinoxaden is improved, but also a chemical stabilization effect of the pinoxaden is effectively improved, and the problems of precipitation due to crystallization at low temperature and chemical stability of the pinoxaden emulsifiable concentrate formulations are solved.

Abstract: The application provides a high-purity thermostable crystal form of a substituted 3-isoxazolidinone compound, a preparation method therefor and an application thereof. The High-purity thermostable crystal form is prepared by a particular method of the present technology and is determined by single-crystal X-ray diffraction as an orthorhombic crystal, featuring a space group of P212121 and lattice parameters of a=9.2301(2) ?, b=11.0751(3) ?, c=12.7554(3) A, ?=90°, ?=90°, and ?=90°. The orthorhombic crystal can be conveniently applied in preparation of agrochemical formulations, such as a suspension concentrate and a water dispersible granule, and the new formulations prepared have a better herbicidal activity and crop safety.