Abstract: A rod-spring structured clamping and loosening device for a downhole belt replacement apparatus includes an upper and a lower cylinder fixed seat. The upper and the lower cylinder fixed seat are respectively connected to a first and a second set of pull rods, and each set of the pull rods pass through a first transition plate, a second transition plate, and a third transition plate. A first chuck is mounted on a side of the first transition plate facing the upper cylinder fixed seat, a second chuck is mounted on a side of the third transition plate facing the lower cylinder fixed seat, and the first and the second set of the pull rods are fixed at the first and the second chuck. A disc spring is mounted between the first and the second transition plate, and a jack is mounted between the second and the third transition plate.

Abstract: This present invention relates to BCMA binders (e.g. antibodies) and chimeric antigen receptor (CAR) constructs comprising a BCMA antigen binding molecule. The BCMA binders specifically bind to BCMA. The present BCMA CARs further comprise a hinge region (e.g., CD28 hinge), a transmembrane domain, and one or more intracellular NK cell signalling domains. NK cells expressing a BCMA CAR has increased efficacy in killing cancer cells. Provided herein also include therapeutic uses of the BCMA binders and BCMA CARs.

Abstract: The disclosure provides a separation device for steel cord cores of the conveyor belt, relates to conveyor belt steel cord core separation technology and solves the problems of high labor intensity and long time consumption when separating steel cord cores of a conveyor belt joint. The separation device comprises a mount, cutting mechanism and a conveying mechanism. The cutting mechanism is connected to the mount and is provided with knives, configured to separate steel cord cores of a joint site of a conveyor belt and arranged along the width direction of the conveyor belt. The dimension of the knife along the width direction of the conveyor belt is greater than or equal to the width of the conveyor belt. The conveying mechanism is fixedly connected to the mount and configured to move the conveyor belt joint site along the knife. The separation device is configured to separate steel cord cores of a conveyor belt joint site.

Abstract: The present invention provides a device for testing an allergen antibody in a liquid sample, and the device includes a testing area and a water absorption area, where the testing area is used to contact with liquid, and the water absorption area is located downstream of the testing area and used to absorb the liquid from the testing area; a plurality of first receptors are immobilized onto the testing area, and each of the first receptors is capable to specifically bind to a plurality of different allergen antibodies in the liquid sample. Such a device can be used to once test the presence or absence or level of a plurality of allergen antibodies in the liquid sample, thereby achieving an efficient and convenient testing effect.

Abstract: This present invention relates to BCMA binders (e.g. antibodies) and chimeric antigen receptor (CAR) constructs comprising a BCMA antigen binding molecule. The BCMA binders specifically bind to BCMA. The present BCMA CARs further comprise a hinge region (e.g., CD28 hinge), a transmembrane domain, and one or more intracellular NK cell signalling domains. NK cells expressing a BCMA CAR has increased efficacy in killing cancer cells. Provided herein also include therapeutic uses of the BCMA binders and BCMA CARs.

Abstract: A lifting mechanism includes a lifting beam, a hanging portion suspended below the lifting beam and including a hanging base, a hanging chain, a movable sprocket disposed on the hanging base, a distance adjusting sprocket, and a power mechanism. The distance adjusting sprocket and the power mechanism are arranged side by side and separately on the lifting beam. The power mechanism includes a fixed sprocket and a driving portion. The fixed sprocket is driven by the driving portion to drive the hanging chain to move, so as to lift or lower the hanging portion. An end of the hanging chain is fixed to the lifting beam, and the other end of the hanging chain engages the movable sprocket, the fixed sprocket, and the distance adjusting sprocket, or the other end of the hanging chain engages the movable sprocket, the distance adjusting sprocket, and the fixed sprocket.

Abstract: Provided herein are methods for treating cancer, comprising administering to a subject having cancer a therapeutically effective amount of an anti-GITR antibody alone or together with an anti-PD-1 or anti-PD-L1 antibody.

Abstract: Provided herein are methods for treating cancer, comprising administering to a subject having cancer a therapeutically effective amount of an anti-GITR antibody alone or together with an anti-PD-1 or anti-PD-L1 antibody.

Abstract: A vertical lifting device and method are provided. The vertical lifting device includes a fixed frame fixed to a foundation. A first cavity allowing passage of a lifting rope is provided in the middle of the fixed frame. A sliding frame moving horizontally on the fixed frame is arranged above the fixed frame. A second cavity allowing passage of the lifting rope is provided in the middle of the sliding frame. At least two stepping vehicles alternately lowering or lifting weights are arranged on the sliding frame and move on the sliding frame. The stepping vehicles are spaced in preset distances. The lifting rope penetrates through the stepping vehicles in sequence. Each stepping vehicle is provided with a clamping part clamping the lifting rope and a driving mechanism driving the stepping vehicle to move on the sliding frame.

Abstract: Provided are a suspension device of a monorail crane and a monorail crane. The suspension device includes a suspension box and at least one set of suspension wheels; the suspension box is provided with a receiving groove for receiving at least one set of the suspension wheels; the receiving groove is provided with a first suspension wheel and a second suspension wheel; a first gap is formed the first suspension wheel and the second suspension wheel; the monorail includes at least a first track on which the first suspension wheel is placed and a second track on which the second suspension wheel is placed; a spacer is provided between the first track and the second track; the first gap can accommodate at least the spacer; the suspension devices each further includes a braking mechanism fixed to the suspension box.

Abstract: A lifting mechanism includes a lifting beam, a hanging portion suspended below the lifting beam and including a hanging base, a hanging chain, a movable sprocket disposed on the hanging base, a distance adjusting sprocket, and a power mechanism. The distance adjusting sprocket and the power mechanism are arranged side by side and separately on the lifting beam. The power mechanism includes a fixed sprocket and a driving portion. The fixed sprocket is driven by the driving portion to drive the hanging chain to move, so as to lift or lower the hanging portion. An end of the hanging chain is fixed to the lifting beam, and the other end of the hanging chain engages the movable sprocket, the fixed sprocket, and the distance adjusting sprocket, or the other end of the hanging chain engages the movable sprocket, the distance adjusting sprocket, and the fixed sprocket.

Abstract: Provided herein are methods for treating cancer, comprising administering to a subject having cancer a therapeutically effective amount of an anti-GITR antibody alone or together with an anti-PD-1 or anti-PD-L1 antibody.

Abstract: A vertical lifting device and method are provided. The vertical lifting device includes a fixed frame fixed to a foundation. A first cavity allowing passage of a lifting rope is provided in the middle of the fixed frame. A sliding frame moving horizontally on the fixed frame is arranged above the fixed frame. A second cavity allowing passage of the lifting rope is provided in the middle of the sliding frame. At least two stepping vehicles alternately lowering or lifting weights are arranged on the sliding frame and move on the sliding frame. The stepping vehicles are spaced in preset distances. The lifting rope penetrates through the stepping vehicles in sequence. Each stepping vehicle is provided with a clamping part clamping the lifting rope and a driving mechanism driving the stepping vehicle to move on the sliding frame.

Abstract: The present disclosure discloses a suspension device of a monorail crane and a monorail crane. The suspension device the suspension device comprises a suspension box and at least one set of suspension wheels; the suspension box is provided with a receiving groove for receiving at least one set of the suspension wheels; the receiving groove is provided with a first suspension wheel and a second suspension wheel; a first gap is formed the first suspension wheel and the second suspension wheel; the monorail comprises at least a first track on which the first suspension wheel is placed and a second track on which the second suspension wheel is placed; a spacer is provided between the first track and the second track; the first gap can accommodate at least the spacer; the suspension devices each further comprises a braking mechanism fixed to the suspension box.

Abstract: The present invention relates to a wire rope suspension device, control method and multi-rope friction lift system, the device comprising: a first beam (6) and a second beam (9) which are passed by a wire rope (1) and fixed to the wire rope (1); a suspension joint (15), for connecting a lifting container (30); a suspension cylinder (14), having two ends respectively connected to the second beam (9) and the suspension joint (15); a wedge joint (8), being disposed in an accommodating chamber provided inside the second beam (9); and a wire rope bias limiting mechanism, being disposed between the wedge joint (8) and the second beam (9), for driving the wedge joint (8) to lock a wire rope section on one side of the wedge joint (8) itself and releasing movement restriction of a wire rope section on the other side of the wedge joint (8), when the second beam (9) has a displacement with respect to the first beam (6) in a predetermined direction. The present invention allows a convenient rope adjustment operation.

Abstract: A composite material packaged fiber grating sensor and a manufacturing method thereof. The sensor includes a fiber grating sensor component, a composite material coverage layer, a resin package layer and a composite material substrate layer. In the sensor, a temperature fiber grating and a strain fiber grating are packaged in a composite material structure, so that the structure is light and simple, its computability with the composite material is good, the measurement accuracy is high, and the survival rate and the service life of the installed sensor can be greatly improved, the sensor component can be externally pasted on to or inter-implanted in a composite material structural part, and can be applied to the distributed online health monitoring on the structural part. The manufacturing method of the composite material packaged fiber grating sensor is simple, efficient and stable, and is suitable for rapid mass production by enterprises.

Abstract: The present invention relates to a wire rope suspension device, control method and multi-rope friction lift system, the device comprising: a first beam (6) and a second beam (9) which are passed by a wire rope (1) and fixed to the wire rope (1); a suspension joint (15), for connecting a lifting container (30); a suspension cylinder (14), having two ends respectively connected to the second beam (9) and the suspension joint (15); a wedge joint (8), being disposed in an accommodating chamber provided inside the second beam (9); and a wire rope bias limiting mechanism, being disposed between the wedge joint (8) and the second beam (9), for driving the wedge joint (8) to lock a wire rope section on one side of the wedge joint (8) itself and releasing movement restriction of a wire rope section on the other side of the wedge joint (8), when the second beam (9) has a displacement with respect to the first beam (6) in a predetermined direction. The present invention allows a convenient rope adjustment operation.

Abstract: An interface display method, a communication terminal and a computer storage medium. The interface display method comprises: detecting the number of SIM card(s) in a terminal; and according to the number of the SIM card(s), determining a display interface of the terminal.

Abstract: A composite material packaged fiber grating sensor and a manufacturing method thereof. The sensor includes a fiber grating sensor component, a composite material coverage layer, a resin package layer and a composite material substrate layer. In the sensor, a temperature fiber grating and a strain fiber grating are packaged in a composite material structure, so that the structure is light and simple, its computability with the composite material is good, the measurement accuracy is high, and the survival rate and the service life of the installed sensor can be greatly improved, the sensor component can be externally pasted on to or inter-implanted in a composite material structural part, and can be applied to the distributed online health monitoring on the structural part. The manufacturing method of the composite material packaged fiber grating sensor is simple, efficient and stable, and is suitable for rapid mass production by enterprises.

Abstract: An interface display method, a communication terminal and a computer storage medium. The interface display method comprises: detecting the number of SIM card(s) in a terminal; and according to the number of the SIM card(s), determining a display interface of the terminal.