Patents by Inventor Haiqing Yuan

Haiqing Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240125128
    Abstract: This invention discloses digitally printed plate, the manufacturing method and applications thereof, is characterized in that the digitally printed plate is of respectively from top to bottom surface lacquer layer, texture layer, second wear layer, first wear layer, pattern layer, bottom lacquer layer, base layer. The digitally printed plated has various patterns, with sufficient materials, printing unrepeatable stereoscopic pattern is possible, so it can satisfy customers' personalized customization requirements, without wasting abundant time or cost, and with process reduced, production efficiency is improved, enabling order manufacturing order insert and sample making at any time.
    Type: Application
    Filed: March 24, 2021
    Publication date: April 18, 2024
    Inventors: Jun Yuan, Quanshan Cheng, Juan Chen, Haiqing Qian, Rong Jiang, Yuan Liu
  • Publication number: 20240066850
    Abstract: The invention discloses a high strength fireproof board, which has two structures. The first structure is a three-layer hot pressed composite structure, which is composed of fiber layer, foaming fiber layer and fiber layer respectively from top to bottom, and the second structure is composed of hot-pressed fiber layer. The invention also discloses a wear resistant fireproof decorative panel consisting of a high strength fireproof board which is hot pressed at one time, or can be hot pressed twice, or composite molded after glue coated. The invention also discloses a manufacturing method for high strength fireproof board and wear resistant decorative panel based on high strength fireproof base board. The stated high strength fireproof board and wear resistant decorative panel are made of thermosetting resin and have the characteristics of flame retardant, wear resistant, high, and low temperature resistant, sound absorbing and antistatic.
    Type: Application
    Filed: March 24, 2021
    Publication date: February 29, 2024
    Inventors: Jun Yuan, Jinshan Cheng, Juan Chen, Haiqing Qian, Chunyang Wang
  • Patent number: 11876347
    Abstract: A broadband tuning system includes a first chip and a second chip. The first chip includes a first light amplification region, a first forward grating region and a first backward grating region that are sequentially arranged in a first direction. The first light amplification region is configured to amplify a first light source and to turn on or turn off the first light source, and the first forward grating region and the first backward grating region are configured to tune the first light source. The second chip includes a second light amplification region, a second forward grating region and a second backward grating region that are sequentially arranged in a second direction. The second light amplification region is configured to amplify a second light source and to turn on or turn off the second light source, and the second forward grating region and the second backward grating region are configured to tune the second light source.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: January 16, 2024
    Assignee: INSTITUTE OF SEMICONDUCTORS, CHINESE ACADEMY OF SCIENCES
    Inventors: Wenhui Sun, Wei Chen, Nuannuan Shi, Ninghua Zhu, Ming Li, Xin Wang, Jinhua Bai, Haiqing Yuan, Wei Li, Yu Liu
  • Publication number: 20230295159
    Abstract: Disclosed are an ATX inhibitor, a preparation method therefor, and the use thereof, which belong to the technical field of pharmaceutical chemistry. In particular, the ATX inhibitor is a compound having the structure of formula I?, or a pharmaceutically acceptable salt, an ester, an isomer, a solvate, a prodrug or an isotope marker thereof. Compared with the existing ATX inhibitor GLPG-1690, the ATX inhibitor has higher inhibitory activity, also has excellent efficacy, in vitro/in vivo pharmacokinetic properties and safety, and has broad clinical application prospects.
    Type: Application
    Filed: July 8, 2021
    Publication date: September 21, 2023
    Inventors: Cheng PENG, Mengfei QIAN, Xiashi LV, Jin WU, Wei YIN, Fengyou LIU, Yi JIN, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • Publication number: 20230293500
    Abstract: An AK3287 formulation, and a preparation method therefor and an application thereof. In mass fraction, the formulation comprises: 0.05-20% of AK3287; 0-30% of an absorption enhancer; 5-99.95% of an oil-phase substance; 0-25% of an emulsifier; 0-5% of a preservative; and 0-70% of water, wherein the structure of AK3287 is shown in the drawing. AK3287 molecules in the formulation have high exposure in the skin, and the formulation can reduce the thickness of the skin at a scar and the ratio of the maximum thickness of the skin at the scar to the thickness of the normal skin; moreover, the relative density of TGF-? and type I collagen in the skin is reduced.
    Type: Application
    Filed: September 2, 2021
    Publication date: September 21, 2023
    Inventors: Cheng PENG, Yuping LI, Chunyan ZHOU, Gang ZOU, Haiqing YUAN, Jim Zhen WU
  • Publication number: 20230107378
    Abstract: The present disclosure provides an elastase inhibitor prodrug and use thereof, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer or solvate thereof, prodrugs or isotopically labeled compound. Compared with the compound 52 (control example) in WO 2018/175173 A1, the compound disclosed herein has the advantages of high pulmonary exposure and long half-life. The prodrugs of the present disclosure significantly increase the concentration and residence time of the active compound (control example) in the lungs with significant improvements in pharmacokinetics in vivo compared to the control example.
    Type: Application
    Filed: March 8, 2021
    Publication date: April 6, 2023
    Inventors: Cheng PENG, Yang ZHOU, Yanfei WANG, Mengfei QIAN, Zhaoxiong CAI, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • Publication number: 20230090060
    Abstract: The present disclosure provides the synthesis and application of respiratory syncytial virus inhibitor, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer, solvate, prodrug or isotope label thereof. Compared with the existing inhibitors, the compounds of formula I have the advantages of superior activity and higher exposure in vivo.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 23, 2023
    Inventors: Cheng PENG, Xiashi LV, Mengfei QIAN, Wei YIN, Chaojun GONG, Jian HAN, Wei SHEN, Danbin LI, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • Publication number: 20220387443
    Abstract: Disclosed is a pharmaceutical unit dosage composition including a plurality of enteric coated micro pellets. Each enteric coated micro pellet includes a core bead, an optional first sealing layer, an API layer including a Compound (I) having the following structure or a pharmaceutically acceptable salt thereof, an optional second sealing layer, and an enteric coating layer. Also disclosed is a method for the treatment and prophylaxis of RSV diseases including providing a Compound (I) and administering to a patient in need thereof a therapeutically effective amount of the Compound (I) so that t½ of the Compound (I) is about 6 to 13 hours.
    Type: Application
    Filed: October 29, 2020
    Publication date: December 8, 2022
    Inventors: Cheng PENG, Zhen Jim WU, Yuping LI, Chunyan ZHOU, Yuanyuan LI, Stephen TOOVEY, Haiqing YUAN
  • Publication number: 20220081434
    Abstract: The present disclosure provides a series of dihydroisoquinoline compounds or a pharmaceutically acceptable salt, ester, isomer, solvate, hydrate, prodrug, or isotopically labeled compounds thereof, having the structure of general formula I: (I). The compounds have an extremely strong activity for inhibiting Hepatitis B surface antigen and has an extremely strong activity for inhibiting Hepatitis B virus DNA. In addition, the compounds feature high bioavailability and can exhibit efficacy with a low dosage, which reduces the potential toxicity of the compounds.
    Type: Application
    Filed: January 7, 2020
    Publication date: March 17, 2022
    Inventors: Cheng PENG, Shaoyun ZHANG, Xiaogang LAI, Chaojun GONG, Jian HAN, Baolin XU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Publication number: 20210281044
    Abstract: A broadband tuning system includes a first chip and a second chip. The first chip includes a first light amplification region, a first forward grating region and a first backward grating region that are sequentially arranged in a first direction. The first light amplification region is configured to amplify a first light source and to turn on or turn off the first light source, and the first forward grating region and the first backward grating region are configured to tune the first light source. The second chip includes a second light amplification region, a second forward grating region and a second backward grating region that are sequentially arranged in a second direction. The second light amplification region is configured to amplify a second light source and to turn on or turn off the second light source, and the second forward grating region and the second backward grating region are configured to tune the second light source.
    Type: Application
    Filed: December 29, 2020
    Publication date: September 9, 2021
    Inventors: Wenhui Sun, Wei CHEN, Nuannuan SHI, Ninghua ZHU, Ming Li, Yu LIU, Xin WANG, Jinhua BAI, Haiqing YUAN, Wei LI
  • Patent number: 11046644
    Abstract: The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: June 29, 2021
    Assignee: ALLERGAN, INC.
    Inventors: Haiqing Yuan, Richard L. Beard, Xiaoxia Liu, John E. Donello, Veena Viswanath, Michael E. Garst
  • Patent number: 10717730
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: July 21, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu, Xiashi Lv, Xiaogang Lai, Shaoyun Zhang
  • Publication number: 20200207755
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Inventors: Cheng PENG, Xiashi LV, Xiaogang LAI, Shaoyun ZHANG, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Patent number: 10647712
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 12, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Qing Xu, Teng Feng, Xiashi Lv, Xiaogang Lai, Rui Cui, Shaoyun Zhang, Jian Han, Chaojun Gong, Zhaoxiong Cai, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu
  • Publication number: 20200109110
    Abstract: The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
    Type: Application
    Filed: May 13, 2019
    Publication date: April 9, 2020
    Inventors: HAIQING YUAN, RICHARD L. BEARD, XIAOXIA LIU, JOHN E. DONELLO, VEENA VISWANATH, MICHAEL E. GARST
  • Publication number: 20190389855
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: January 10, 2018
    Publication date: December 26, 2019
    Inventors: Cheng PENG, Qing XU, Teng FENG, Xiashi LV, Xiaogang LAI, Rui CUI, Shaoyun ZHANG, Jian HAN, Chaojun GONG, Zhaoxiong CAI, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Publication number: 20190211003
    Abstract: The invention discloses 20,23-modified novel derivatives of 16-membered demycarosyltylonolide antibiotics, which are useful against bacterial and mycoplasmic pathogens in humans and animals. Also claimed are pharmaceutical compositions of such derivatives and their use in treating bacterial and mycoplasmic infections in humans and animals.
    Type: Application
    Filed: March 17, 2019
    Publication date: July 11, 2019
    Applicant: VICTOR PHARMA CO., LTD. ZHENJIANG
    Inventors: Haiqing YUAN, Wenjiang HUANG
  • Patent number: 10287243
    Abstract: The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: May 14, 2019
    Assignee: ALLERGAN, INC.
    Inventors: Haiqing Yuan, Richard L. Beard, Xiaoxia Liu, John E. Donello, Veena Viswanath, Michael E. Garst
  • Patent number: 10287275
    Abstract: The invention discloses 20,23-modified novel derivatives of 16-membered demycarosyltylonolide antibiotics, which are useful against bacterial and mycoplasmic pathogens in humans and animals. Also claimed are pharmaceutical compositions of such derivatives and their use in treating bacterial and mycoplasmic infections in humans and animals.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: May 14, 2019
    Assignee: VICTOR PHARMA CO., LTD. ZHENJIANG
    Inventors: Haiqing Yuan, Wenjiang Huang
  • Publication number: 20180148434
    Abstract: The invention discloses 20,23-modified novel derivatives of 16-membered demycarosyltylonolide antibiotics, which are useful against bacterial and mycoplasmic pathogens in humans and animals. Also claimed are pharmaceutical compositions of such derivatives and their use in treating bacterial and mycoplasmic infections in humans and animals.
    Type: Application
    Filed: July 2, 2015
    Publication date: May 31, 2018
    Inventors: Haiqing Yuan, Wenjiang Huang