Abstract: The invention relates to quinazolinone derivatives and of formula (I) as defined herein and processes for the production of said derivatives. Also included in the invention are pharmaceutical compositions containing a compound of said formula (I) as active ingredient and the use of said compounds and compositions as anti-inflammatory agents.

Abstract: The present invention relates to certain new 7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compound, to a process for their production and to their use as agents which have an influence on the central nervous system.The ring system according to the invention has not hitherto been described in the literature.

Abstract: The invention relates to S-alkyl 3-alkylthiopropionothioates of Formula (I) as defined herein. Also included in the invention are methods for the manufacture of said S-alkylthiopropionothioates, compositions containing them and the use of said compounds and compositions for the treatment of inflammatory processes.

Abstract: The invention relates to pharmaceutical compositions containing as an active ingredient a dipeptide or an acid salt or a base addition salt thereof or a stereoisomer thereof, said dipeptide being those of the formulaR--Phe--Trp--R.sub.1in whichPhe denote the radical ##STR1## Trp denotes the radical ##STR2## R denotes a hydrogen atom or a C.sub.1 to C.sub.6 optionally substituted alkanoyl group andR.sub.1 denotes a hydroxyl, C.sub.1 to C.sub.4 alkoxy, amino, C.sub.1 to C.sub.4 alkylamino or di-C.sub.1 to C.sub.4 alkylamino group.

Abstract: The invention relates to compositions containing S-benzyl 3-benzylthiopropionothioate for the treatment of inflammatory processes. Also included in the invention are methods for combating illnesses caused by inflammatory, processes, which methods involve use of medicaments containing said S-benzyl 3-benzylthiopropionothioate.

Abstract: The invention relates to 2-oxo-1-pyrrolidineacetic acid compounds, useful as psychopharmacological agents. Also included in the invention are pharmaceutical compositions containing said compounds and methods for the use of said compounds and compositions.

Abstract: The present invention provides, inter alia, antiphlogistically effective agents, including pharmaceutical compositions containing said agents. Also included are methods for the use of said agents. The active compounds are those of the formula ##STR1## or an ester thereof, in which X denotes a hydrogen atom, an alkyl group, an alkoxy group, an alkylthio group, an alkylsulphinyl or alkylsulphonyl group or a hydroxyl or mercapto group,Y denotes a grouping ##STR2## in which R denotes a hydrogen atom or an alkyl group, andZ denotes a hydroxyl group or an alkoxy or alkylthio group, at least one of the substituents X or Z in each case denoting a sulphur-containing radical.

Abstract: This invention relates to dehydropeptides containing a tryptophan moiety useful as tumour-resolving and/or histolytic medicaments. Also included in the invention are methods for the preparation of said dehydropeptides, compositions containing said dehydropeptides and methods for the use of said dehydropeptides and dehydropeptide compositions.

Abstract: The present invention provides, inter alia, antiphlogistically effective agents, including pharmaceutical compositions containing said agents. Also included are methods for the use of said agents. The active compounds are those of the formula ##STR1## or an ester thereof, in which X denotes a hydrogen atom, an alkyl group, an alkoxy group, an alkylthio group, an alkylsulphinyl or alkylsulphonyl group or a hydroxyl or mercapto group,Y denotes a grouping ##STR2## in which R denotes a hydrogen atom or an alkyl group, andZ denotes a hydroxyl group or an alkoxy or alkylthio group, at least one of the substituents X or Z in each case denoting a sulphur-containing radical.

Abstract: Novel 2-benzopyranone compounds of the formula ##STR1## wherein X is a 3,4,5-trimethoxybenzoyl group or a 3,4,5-trimethoxycinnamoyl group; and eachR individually is selected from the group consisting of alkylamino and dialkylamino in which one carbon atom in the alkyl moiety may be replaced by an oxygen atom and one hydrogen atom may be replaced by a hydroxyl group which may in turn be esterified with a 3,4,5-trimethoxybenzoyl or 3,4,5-trimethoxycinnamoyl group; amino substituted once or twice by alkenyl, aralkyl, or cycloalkyl; ora 4- to 7-membered N-containing heterocyclic ring linked through a nitrogen atom and which contains up to 3 hetero atoms, which heterocyclic ring may be substituted by phenyl, alkyl or hydroxyalkyl, wherein the hydroxy group may be esterfied by a 3,4,5-trimethoxy benzoyl or 3,4,5-trimethoxy cinnamoyl group;or a salt of each compound with a physiologically acceptable acid; possess outstanding activity as coronary dilators. Processes for producing such compounds are also disclosed.

Abstract: The invention includes 5,6-dimethylpyrrolo [2,3-d]-pyrimidines (and method for their manufacture) of the formula ##STR1## or an acid-addition salt thereof, in which R is amino or hydroxy,R.sub.1 is halogen, nitro, C.sub.1 --C.sub.6 alkyl or alkoxy or CF.sub.3 and, where R is hydroxy, is also hydrogen,R.sub.2 is hydrogen, halogen or C.sub.1 --C.sub.6 -alkyl or alkoxy, andn is 1 or 2.Also included in the invention are pharmaceutical compositions containing said pyrrolo [2,3-d]-pyrimidines and the use of said compounds and compositions for treating CNS illnesses or inflammations.

Abstract: Novel 2-benzopyranone compounds of the formula ##STR1## wherein X is a 3,4,5-trimethoxybenzoyl group or a 3,4,5-trimethoxycinnamoyl group; and eachR individually is selected from the group consisting of alkylamino and dialkylamino in which one carbon atom in the alkyl moiety may be replaced by an oxygen atom and one hydrogen atom may be replaced by a hydroxyl group which may in turn be esterified with a 3,4,5-trimethoxybenzoyl or 3,4,5-trimethoxycinnamoyl group; amino substituted once or twice by alkenyl, aralkyl, or cycloalkyl; or a 4- to 7-membered N-containing heterocyclic ring linked through a nitrogen atom and which contains up to 3 hetero atoms, which heterocyclic ring may be substituted by phenyl, alkyl or hydroxyalkyl, wherein the hydroxy group may be esterified by a 3,4,5-trimethoxy benzoyl or 3,4,5-trimethoxy cinnamoyl group;Or a salt of each compound with a physiologically acceptable acid; possess outstanding activity as coronary dilators. Processes for producing such compounds are also disclosed.

Abstract: The present invention pertains to novel (2-oxo-pyrrolidine-1)-acetic hydrazides, methods for preparation and subsequent treatment therewith, and pharmaceutical preparations containing the same.

Abstract: The present invention pertains to novel (2-oxo-pyrrolidine-1)-acetic hydrazides, methods for preparation and subsequent treatment therewith, and pharmaceutical preparations containing the same.

Abstract: [1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYL-3-INDOLE]-ACETOXYACETIC ACID OF THE FORMULA ##SPC1##Possesses outstanding antiphlogistic activity without the side effects of certain conventional antiphlogistic pharmaceuticals.