Patents by Inventor Hairong Zheng
Hairong Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10780437Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity used to accommodate a solution containing particles and a ultrasonic emission device used to emit ultrasound, and further comprising a phononic crystal plate placed in the microcavity. The phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.Type: GrantFiled: October 10, 2015Date of Patent: September 22, 2020Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Hairong Zheng, Fei Li, Feiyan Cai, Long Meng, Chen Wang, Chengxiang Zhang, Weibao Qiu, Yongchuan Li, Fei Yan, Lili Niu, Liufeng Geng, Chaowei Xu
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Patent number: 10782379Abstract: A method, an apparatus, and a device for magnetic resonance chemical shift encoding imaging are provided. The method includes in a phasor-error spectrum established based on a simplified multi-point magnetic resonance signal model, determining a pixel point having a unique phase factor value and causing the phasor-error spectrum to reach a local minimum value as an initial seed point; estimating a phase factor value of a pixel point to be estimated according to the initial seed point to obtain a field map; mapping and merging the field maps at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain a phase factor value of a reconstructed pixel point to be estimated.Type: GrantFiled: December 30, 2015Date of Patent: September 22, 2020Assignee: SHENZHEN INSTITUTES OF ADVANCES TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
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Publication number: 20200292651Abstract: The present invention provides a magnetic resonance temperature imaging method and apparatus, and relates to the field of magnetic resonance. According to the magnetic resonance temperature imaging method and apparatus, accuracy and precision of a water-fat tissue temperature image at a current moment are improved by using a two-step iterative temperature estimation algorithm, a magnetic resonance signal model includes multiple fat peaks, and a fourth strength amplitude value of a water signal, a fourth strength amplitude value of a fat signal, a fourth field drift caused by a non-uniform main magnetic field, and the water-fat tissue temperature image at the current moment that minimize a difference between signal strength and signal strength before fitting are estimated.Type: ApplicationFiled: June 1, 2020Publication date: September 17, 2020Inventors: Hairong ZHENG, Xin LIU, Chao ZOU, Chuanli CHENG, Yangzi QIAO, Changjun TIE
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Patent number: 10746833Abstract: A magnetic resonance vessel wall imaging method and device. The method comprises: applying a set pulse sequence into an imaging region, wherein the set pulse sequence comprises, in chronological order, a Delay Alternating with Nutation for Tailored Excitation (DANTE) pulse train, a variable flip angle train of a three-dimensional fast spin echo (SPACE), and a flip-down pulse train (S110); acquiring a magnetic resonance signal generated in the imaging region, and reconstructing a magnetic resonance images of the vessel wall in the imaging region according to the magnetic resonance signal (S120). By adding the flip-down pulse train behind the variable flip angle train of the three-dimensional fast spin echo (SPACE), the cerebrospinal fluid signals of the whole brain can be further suppressed effectively and uniformly, and the DANTE pulse train promotes the vessel wall imaging of the head and neck jointing portion.Type: GrantFiled: May 22, 2018Date of Patent: August 18, 2020Assignee: SHENZHEN INSTITUTES ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Lei Zhang, Yiu-Cho Chung, Xin Liu, Xiaoqing Hu, Hairong Zheng
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Publication number: 20200256942Abstract: Provided are a parallel magnetic resonance imaging method and apparatus based on adaptive joint sparse codes and a computer-readable medium. The method includes solving an l2?lF?l2,1 minimization objective, where the l2 norm is a data fitting term, the lF norm is a sparse representation error, and the l2,1 mixed norm is the joint sparsity constraining across multiple channels; separately updating each of a sparse matrix, a dictionary and K-space data with a corresponding algorithm, and obtaining a reconstructed image by a sum of root mean squares of all the channels. The joint sparsity of the channels is developed using the norm l2,1. In this manner, calibration is not required while information sparsity is developed. Moreover, the method is robust.Type: ApplicationFiled: December 1, 2017Publication date: August 13, 2020Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGYInventors: Shanshan WANG, Dong LIANG, Sha TAN, Xin LIU, Hairong ZHENG
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Publication number: 20200241099Abstract: A method, an apparatus, and a device for magnetic resonance chemical shift encoding imaging are provided. The method includes in a phasor-error spectrum established based on a simplified multi-point magnetic resonance signal model, determining a pixel point having a unique phase factor value and causing the phasor-error spectrum to reach a local minimum value as an initial seed point; estimating a phase factor value of a pixel point to be estimated according to the initial seed point to obtain a field map; mapping and merging the field maps at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain a phase factor value of a reconstructed pixel point to be estimated.Type: ApplicationFiled: December 30, 2015Publication date: July 30, 2020Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Hairong ZHENG, Xin LIU, Chuanli CHENG, Chao ZOU
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Publication number: 20200229794Abstract: A method and a device for acquiring biomechanical parameters based on an ultrasonic elastomyogram are provided, wherein the method includes: synchronously collecting a dynamic myodynamics image sequence and a dynamic elasticity image sequence of a single skeletal muscle under continuous stretching; acquiring a myodynamics parameter corresponding to each myodynamics image in the dynamic myodynamics image sequence and an elasticity modulus value corresponding to each elasticity image in the dynamic elasticity image sequence respectively; and generating an ultrasonic elastomyogram curve with the myodynamics parameter as the abscissa and the synchronized elasticity modulus value as the ordinate, and estimating a muscle biomechanical parameter based on the ultrasonic elastomyogram curve. Dynamically changing biomechanical parameters can be obtained, and the obtained muscle biomechanical parameters have relatively high accuracy.Type: ApplicationFiled: December 26, 2017Publication date: July 23, 2020Applicant: Shenzhen Institutes of Advanced TechnologyInventors: Yang XIAO, Hairong ZHENG, Congzhi WANG, Lili NIU, Zhiting DENG
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Publication number: 20200187907Abstract: Provided is an ultrasonic transducer and a preparation method thereof. The ultrasonic transducer includes a housing. A piezoelectric layer is disposed in the housing and includes at least two piezoelectric array elements. A frequency interval between the piezoelectric array elements is 50 kHz to 1.2 MHz. An acoustic lens is disposed at a front end of the piezoelectric layer and is used for ensuring that the piezoelectric array elements having different frequencies have a common focus.Type: ApplicationFiled: July 26, 2018Publication date: June 18, 2020Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Weibao Qiu, Wu Sun, Min Su, Suzi Liang, Zhiqiang Zhang, Hairong Zheng
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Method and apparatus for denoising magnetic resonance diffusion tensor, and computer program product
Patent number: 10620287Abstract: The application provides a method, apparatus and computer program product for denoising a magnetic resonance diffusion tensor, wherein the method comprises: collecting data of K space; calculating a maximum likelihood estimator of a diffusion tensor according to the collected data of K space; calculating a maximum posterior probability estimator of the diffusion tensor by using sparsity of the diffusion tensor and sparsity of a diffusion parameter and taking the calculating maximum likelihood estimator as an initial value; and calculating the diffusion parameter according to the calculated maximum posterior probability estimator. The application solves the technical problem in the prior art of how to realize high precision denoising of diffusion tensor while not increasing scanning time and affecting spatial resolution, achieves the technical effects of effectively suppressing noises in the diffusion tensor and improving the estimation accuracy of the diffusion tensor.Type: GrantFiled: June 9, 2017Date of Patent: April 14, 2020Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Xi Peng, Dong Liang, Xin Liu, Hairong Zheng -
Publication number: 20200038692Abstract: Provided is a conscious animal ultrasonic neural regulation device, including a pulse signal generation module, a transducer module and a fixing module. The pulse signal generation module is configured to generate a pulse signal with high energy. The ultrasonic transducer module is configured to convert the pulse signal into an ultrasound. The fixing module includes an upper fixing module and a lower fixing module. The upper fixing module is configured to fix the ultrasonic transducer module, and the lower fixing module is configured to be fixed on an animal neural regulation target point. The upper fixing module and the lower fixing module are connected by a connecting component. The conscious animal neural regulation device of the present disclosure can perform accurate ultrasonic stimulation on a cerebral cortex and subcortex of the animal, thereby exploring and verifying the stimulation effect of the ultrasound on the animal, which is easy in operation and convenient in use.Type: ApplicationFiled: April 21, 2017Publication date: February 6, 2020Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Hairong Zheng, Hui Zhou, Lili Niu, Ruibiao Guo, Long Meng, Yongchuan Li, Min Su, Jiquing Huang, Ming Qian
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Publication number: 20190374764Abstract: The present disclosure is to manipulate the particles in any path in a non-uniform medium. To achieve the objective, the present disclosure provides the system for manipulating the particles based on a time reversal technique including array transducers, a signal reception and transmission control device and a host. The array transducers are communicatively connected to the signal reception and transmission control device. The signal reception and transmission control device is communicatively connected to the host.Type: ApplicationFiled: April 19, 2017Publication date: December 12, 2019Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGYInventors: FEIYAN CAI, Fei LI, Chen WANG, Weibao QIU, Long MENG, Congzhi WANG, Yang XIAO, Hairong ZHENG
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Patent number: 10459052Abstract: Provided are a magnetic resonance chemical-shift-encoded imaging method, apparatus, and device, belonging to the technical field of magnetic resonance imaging. The method comprises: in a phasor-error plot established on the basis of a two-point magnetic resonance signal model, determining to be an initial seed point a pixel having a unique phasor and causing said plot to reach a minimal local value; according to the initial seed point, estimating the phasor value of a to-be-estimated pixel to obtain a field map; mapping and merging the field map at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain the phasor value of the reconstructed to-be-estimated pixel; according to the reconstructed seed point and the phasor value of the reconstructed to-be-estimated pixel, obtaining two separate images having predetermined components.Type: GrantFiled: December 30, 2015Date of Patent: October 29, 2019Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
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Publication number: 20190321229Abstract: Disclosed is an ultrasonic wave generation device for hearing recovery treatment, including an ultrasonic wave generation part. The ultrasonic wave generation part comprises a reference time-delay determination module, an emission sequence parameter determination module and an ultrasonic transducer module. The ultrasonic transducer module is used for emitting actual ultrasonic waves, and the efficiency and precision are improved by focusing by means of a plurality of array elements.Type: ApplicationFiled: February 8, 2017Publication date: October 24, 2019Inventors: Hairong ZHENG, Zhengrong LIN, Lili NIU, Long MENG, Wei ZHOU, Xiaowei HUANG, Kaiyue WANG
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Publication number: 20190053786Abstract: A delayed excitation ultrasonic imaging method includes: generating a regulating clock, and performing, according to the regulating clock, delayed excitation on an ultrasonic transducer once or multiple times; performing data collection on an ultrasonic echo signal of the ultrasonic transducer and signals after each time of performing delayed excitation; synthesizing and superimposing data collected to obtain high sampling rate data; and performing ultrasonic imaging according to the high sampling rate data. A delayed excitation ultrasonic imaging apparatus and system are also provided. By performing delayed excitation on the ultrasonic transducer, the high-frequency ultrasonic imaging is realized by low-frequency sampling and delayed excitation, which can greatly reduce the cost of the ultrasonic imaging system.Type: ApplicationFiled: October 22, 2018Publication date: February 21, 2019Inventors: Weibao QIU, Peitian MU, Hairong ZHENG
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Publication number: 20190011515Abstract: Provided are a magnetic resonance chemical-shift-encoded imaging method, apparatus, and device, belonging to the technical field of magnetic resonance imaging. The method comprises: in a phasor-error plot established on the basis of a two-point magnetic resonance signal model, determining to be an initial seed point a pixel having a unique phasor and causing said plot to reach a minimal local value; according to the initial seed point, estimating the phasor value of a to-be-estimated pixel to obtain a field map; mapping and merging the field map at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain the phasor value of the reconstructed to-be-estimated pixel; according to the reconstructed seed point and the phasor value of the reconstructed to-be-estimated pixel, obtaining two separate images having predetermined components.Type: ApplicationFiled: December 30, 2015Publication date: January 10, 2019Applicant: Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesInventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
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Publication number: 20180369815Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity and a ultrasonic emission device, wherein the microcavity is used to accommodate a solution containing particles, the ultrasonic emission device is used to emit ultrasound, and characterized in further comprising a phononic crystal plate placed in the microcavity, wherein the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.Type: ApplicationFiled: October 10, 2015Publication date: December 27, 2018Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Hairong ZHENG, Fwi LI, Felyan CAI, Long MENG, Chen WANG, Chengxiang ZHANG, Weibao QIU, Yongchuan LI, Fei YAN, Lili NIU, Liufeng GENG, Chaowei XU
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Publication number: 20180267125Abstract: A magnetic resonance vessel wall imaging method and device. The method comprises: applying a set pulse sequence into an imaging region, wherein the set pulse sequence comprises, in chronological order, a Delay Alternating with Nutation for Tailored Excitation (DANTE) pulse train, a variable flip angle train of a three-dimensional fast spin echo (SPACE), and a flip-down pulse train (S110); acquiring a magnetic resonance signal generated in the imaging region, and reconstructing a magnetic resonance images of the vessel wall in the imaging region according to the magnetic resonance signal (S120). By adding the flip-down pulse train behind the variable flip angle train of the three-dimensional fast spin echo (SPACE), the cerebrospinal fluid signals of the whole brain can be further suppressed effectively and uniformly, and the DANTE pulse train promotes the vessel wall imaging of the head and neck jointing portion.Type: ApplicationFiled: May 22, 2018Publication date: September 20, 2018Inventors: Lei ZHANG, Yiu-Cho CHUNG, Xin LIU, Xiaoqing HU, Hairong ZHENG
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Patent number: 10018698Abstract: Disclosed is a magnetic resonance rapid parameter imaging method and system. The method comprises: obtaining a target undersampled magnetic resonance signal (S10); obtaining prior information of a parameter model (S20); performing sequence reconstruction of a target image according to the undersampled magnetic resonance signal and the prior information to obtain a target image sequence (S30); and substituting the target image sequence into the parameter estimation model to obtain object parameters and to generate parametric images (S40).Type: GrantFiled: December 5, 2014Date of Patent: July 10, 2018Assignee: Shenzhen Institutes Of Advanced Technology Chinese Academy Of SciencesInventors: Xi Peng, Dong Liang, Xin Liu, Hairong Zheng
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METHOD AND APPARATUS FOR DENOISING MAGNETIC RESONANCE DIFFUSION TENSOR, AND COMPUTER PROGRAM PRODUCT
Publication number: 20170363702Abstract: The application provides a method, apparatus and computer program product for denoising a magnetic resonance diffusion tensor, wherein the method comprises: collecting data of K space; calculating a maximum likelihood estimator of a diffusion tensor according to the collected data of K space; calculating a maximum posterior probability estimator of the diffusion tensor by using sparsity of the diffusion tensor and sparsity of a diffusion parameter and taking the calculating maximum likelihood estimator as an initial value; and calculating the diffusion parameter according to the calculated maximum posterior probability estimator. The application solves the technical problem in the prior art of how to realize high precision denoising of diffusion tensor while not increasing scanning time and affecting spatial resolution, achieves the technical effects of effectively suppressing noises in the diffusion tensor and improving the estimation accuracy of the diffusion tensor.Type: ApplicationFiled: June 9, 2017Publication date: December 21, 2017Inventors: Xi PENG, Dong LIANG, Xin LIU, Hairong ZHENG -
Publication number: 20170291044Abstract: An ultrasound deep brain stimulation method and system, the ultrasound deep brain stimulation method comprises: medically imaging a head of an animal or a human being, to generate image data; creating a head 3D digital model according to the image data; creating a 3D digital model of an ultrasound transducer array according to structure, density and acoustic parameters information of the ultrasound transducer array; generating a first ultrasound transmitting sequence according to the head 3D digital model, the 3D digital model of the ultrasound transducer array, structure, density and acoustic parameters of the skull and brain tissues, and structure, density and acoustic parameters of the ultrasound transducer array; and controlling the ultrasound transducer array to transmit ultrasound waves in accordance with the first ultrasound transmitting sequence, to implement ultrasound deep brain stimulation to the brain nucleus to be stimulated.Type: ApplicationFiled: June 22, 2017Publication date: October 12, 2017Inventors: Hairong ZHENG, Lili NIU, Congzhi WANG, Ming QIAN, Yang XIAO, Long MENG