Patents by Inventor Hairong Zheng

Hairong Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10780437
    Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity used to accommodate a solution containing particles and a ultrasonic emission device used to emit ultrasound, and further comprising a phononic crystal plate placed in the microcavity. The phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.
    Type: Grant
    Filed: October 10, 2015
    Date of Patent: September 22, 2020
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong Zheng, Fei Li, Feiyan Cai, Long Meng, Chen Wang, Chengxiang Zhang, Weibao Qiu, Yongchuan Li, Fei Yan, Lili Niu, Liufeng Geng, Chaowei Xu
  • Patent number: 10782379
    Abstract: A method, an apparatus, and a device for magnetic resonance chemical shift encoding imaging are provided. The method includes in a phasor-error spectrum established based on a simplified multi-point magnetic resonance signal model, determining a pixel point having a unique phase factor value and causing the phasor-error spectrum to reach a local minimum value as an initial seed point; estimating a phase factor value of a pixel point to be estimated according to the initial seed point to obtain a field map; mapping and merging the field maps at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain a phase factor value of a reconstructed pixel point to be estimated.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: September 22, 2020
    Assignee: SHENZHEN INSTITUTES OF ADVANCES TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
  • Publication number: 20200292651
    Abstract: The present invention provides a magnetic resonance temperature imaging method and apparatus, and relates to the field of magnetic resonance. According to the magnetic resonance temperature imaging method and apparatus, accuracy and precision of a water-fat tissue temperature image at a current moment are improved by using a two-step iterative temperature estimation algorithm, a magnetic resonance signal model includes multiple fat peaks, and a fourth strength amplitude value of a water signal, a fourth strength amplitude value of a fat signal, a fourth field drift caused by a non-uniform main magnetic field, and the water-fat tissue temperature image at the current moment that minimize a difference between signal strength and signal strength before fitting are estimated.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Inventors: Hairong ZHENG, Xin LIU, Chao ZOU, Chuanli CHENG, Yangzi QIAO, Changjun TIE
  • Patent number: 10746833
    Abstract: A magnetic resonance vessel wall imaging method and device. The method comprises: applying a set pulse sequence into an imaging region, wherein the set pulse sequence comprises, in chronological order, a Delay Alternating with Nutation for Tailored Excitation (DANTE) pulse train, a variable flip angle train of a three-dimensional fast spin echo (SPACE), and a flip-down pulse train (S110); acquiring a magnetic resonance signal generated in the imaging region, and reconstructing a magnetic resonance images of the vessel wall in the imaging region according to the magnetic resonance signal (S120). By adding the flip-down pulse train behind the variable flip angle train of the three-dimensional fast spin echo (SPACE), the cerebrospinal fluid signals of the whole brain can be further suppressed effectively and uniformly, and the DANTE pulse train promotes the vessel wall imaging of the head and neck jointing portion.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: August 18, 2020
    Assignee: SHENZHEN INSTITUTES ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Lei Zhang, Yiu-Cho Chung, Xin Liu, Xiaoqing Hu, Hairong Zheng
  • Publication number: 20200256942
    Abstract: Provided are a parallel magnetic resonance imaging method and apparatus based on adaptive joint sparse codes and a computer-readable medium. The method includes solving an l2?lF?l2,1 minimization objective, where the l2 norm is a data fitting term, the lF norm is a sparse representation error, and the l2,1 mixed norm is the joint sparsity constraining across multiple channels; separately updating each of a sparse matrix, a dictionary and K-space data with a corresponding algorithm, and obtaining a reconstructed image by a sum of root mean squares of all the channels. The joint sparsity of the channels is developed using the norm l2,1. In this manner, calibration is not required while information sparsity is developed. Moreover, the method is robust.
    Type: Application
    Filed: December 1, 2017
    Publication date: August 13, 2020
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Shanshan WANG, Dong LIANG, Sha TAN, Xin LIU, Hairong ZHENG
  • Publication number: 20200241099
    Abstract: A method, an apparatus, and a device for magnetic resonance chemical shift encoding imaging are provided. The method includes in a phasor-error spectrum established based on a simplified multi-point magnetic resonance signal model, determining a pixel point having a unique phase factor value and causing the phasor-error spectrum to reach a local minimum value as an initial seed point; estimating a phase factor value of a pixel point to be estimated according to the initial seed point to obtain a field map; mapping and merging the field maps at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain a phase factor value of a reconstructed pixel point to be estimated.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 30, 2020
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong ZHENG, Xin LIU, Chuanli CHENG, Chao ZOU
  • Publication number: 20200229794
    Abstract: A method and a device for acquiring biomechanical parameters based on an ultrasonic elastomyogram are provided, wherein the method includes: synchronously collecting a dynamic myodynamics image sequence and a dynamic elasticity image sequence of a single skeletal muscle under continuous stretching; acquiring a myodynamics parameter corresponding to each myodynamics image in the dynamic myodynamics image sequence and an elasticity modulus value corresponding to each elasticity image in the dynamic elasticity image sequence respectively; and generating an ultrasonic elastomyogram curve with the myodynamics parameter as the abscissa and the synchronized elasticity modulus value as the ordinate, and estimating a muscle biomechanical parameter based on the ultrasonic elastomyogram curve. Dynamically changing biomechanical parameters can be obtained, and the obtained muscle biomechanical parameters have relatively high accuracy.
    Type: Application
    Filed: December 26, 2017
    Publication date: July 23, 2020
    Applicant: Shenzhen Institutes of Advanced Technology
    Inventors: Yang XIAO, Hairong ZHENG, Congzhi WANG, Lili NIU, Zhiting DENG
  • Publication number: 20200187907
    Abstract: Provided is an ultrasonic transducer and a preparation method thereof. The ultrasonic transducer includes a housing. A piezoelectric layer is disposed in the housing and includes at least two piezoelectric array elements. A frequency interval between the piezoelectric array elements is 50 kHz to 1.2 MHz. An acoustic lens is disposed at a front end of the piezoelectric layer and is used for ensuring that the piezoelectric array elements having different frequencies have a common focus.
    Type: Application
    Filed: July 26, 2018
    Publication date: June 18, 2020
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Weibao Qiu, Wu Sun, Min Su, Suzi Liang, Zhiqiang Zhang, Hairong Zheng
  • Patent number: 10620287
    Abstract: The application provides a method, apparatus and computer program product for denoising a magnetic resonance diffusion tensor, wherein the method comprises: collecting data of K space; calculating a maximum likelihood estimator of a diffusion tensor according to the collected data of K space; calculating a maximum posterior probability estimator of the diffusion tensor by using sparsity of the diffusion tensor and sparsity of a diffusion parameter and taking the calculating maximum likelihood estimator as an initial value; and calculating the diffusion parameter according to the calculated maximum posterior probability estimator. The application solves the technical problem in the prior art of how to realize high precision denoising of diffusion tensor while not increasing scanning time and affecting spatial resolution, achieves the technical effects of effectively suppressing noises in the diffusion tensor and improving the estimation accuracy of the diffusion tensor.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: April 14, 2020
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Xi Peng, Dong Liang, Xin Liu, Hairong Zheng
  • Publication number: 20200038692
    Abstract: Provided is a conscious animal ultrasonic neural regulation device, including a pulse signal generation module, a transducer module and a fixing module. The pulse signal generation module is configured to generate a pulse signal with high energy. The ultrasonic transducer module is configured to convert the pulse signal into an ultrasound. The fixing module includes an upper fixing module and a lower fixing module. The upper fixing module is configured to fix the ultrasonic transducer module, and the lower fixing module is configured to be fixed on an animal neural regulation target point. The upper fixing module and the lower fixing module are connected by a connecting component. The conscious animal neural regulation device of the present disclosure can perform accurate ultrasonic stimulation on a cerebral cortex and subcortex of the animal, thereby exploring and verifying the stimulation effect of the ultrasound on the animal, which is easy in operation and convenient in use.
    Type: Application
    Filed: April 21, 2017
    Publication date: February 6, 2020
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong Zheng, Hui Zhou, Lili Niu, Ruibiao Guo, Long Meng, Yongchuan Li, Min Su, Jiquing Huang, Ming Qian
  • Publication number: 20190374764
    Abstract: The present disclosure is to manipulate the particles in any path in a non-uniform medium. To achieve the objective, the present disclosure provides the system for manipulating the particles based on a time reversal technique including array transducers, a signal reception and transmission control device and a host. The array transducers are communicatively connected to the signal reception and transmission control device. The signal reception and transmission control device is communicatively connected to the host.
    Type: Application
    Filed: April 19, 2017
    Publication date: December 12, 2019
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: FEIYAN CAI, Fei LI, Chen WANG, Weibao QIU, Long MENG, Congzhi WANG, Yang XIAO, Hairong ZHENG
  • Patent number: 10459052
    Abstract: Provided are a magnetic resonance chemical-shift-encoded imaging method, apparatus, and device, belonging to the technical field of magnetic resonance imaging. The method comprises: in a phasor-error plot established on the basis of a two-point magnetic resonance signal model, determining to be an initial seed point a pixel having a unique phasor and causing said plot to reach a minimal local value; according to the initial seed point, estimating the phasor value of a to-be-estimated pixel to obtain a field map; mapping and merging the field map at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain the phasor value of the reconstructed to-be-estimated pixel; according to the reconstructed seed point and the phasor value of the reconstructed to-be-estimated pixel, obtaining two separate images having predetermined components.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: October 29, 2019
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
  • Publication number: 20190321229
    Abstract: Disclosed is an ultrasonic wave generation device for hearing recovery treatment, including an ultrasonic wave generation part. The ultrasonic wave generation part comprises a reference time-delay determination module, an emission sequence parameter determination module and an ultrasonic transducer module. The ultrasonic transducer module is used for emitting actual ultrasonic waves, and the efficiency and precision are improved by focusing by means of a plurality of array elements.
    Type: Application
    Filed: February 8, 2017
    Publication date: October 24, 2019
    Inventors: Hairong ZHENG, Zhengrong LIN, Lili NIU, Long MENG, Wei ZHOU, Xiaowei HUANG, Kaiyue WANG
  • Publication number: 20190053786
    Abstract: A delayed excitation ultrasonic imaging method includes: generating a regulating clock, and performing, according to the regulating clock, delayed excitation on an ultrasonic transducer once or multiple times; performing data collection on an ultrasonic echo signal of the ultrasonic transducer and signals after each time of performing delayed excitation; synthesizing and superimposing data collected to obtain high sampling rate data; and performing ultrasonic imaging according to the high sampling rate data. A delayed excitation ultrasonic imaging apparatus and system are also provided. By performing delayed excitation on the ultrasonic transducer, the high-frequency ultrasonic imaging is realized by low-frequency sampling and delayed excitation, which can greatly reduce the cost of the ultrasonic imaging system.
    Type: Application
    Filed: October 22, 2018
    Publication date: February 21, 2019
    Inventors: Weibao QIU, Peitian MU, Hairong ZHENG
  • Publication number: 20190011515
    Abstract: Provided are a magnetic resonance chemical-shift-encoded imaging method, apparatus, and device, belonging to the technical field of magnetic resonance imaging. The method comprises: in a phasor-error plot established on the basis of a two-point magnetic resonance signal model, determining to be an initial seed point a pixel having a unique phasor and causing said plot to reach a minimal local value; according to the initial seed point, estimating the phasor value of a to-be-estimated pixel to obtain a field map; mapping and merging the field map at the highest resolution to obtain a reconstructed field map; determining a reconstructed seed point from the reconstructed field map, and estimating the reconstructed seed point to obtain the phasor value of the reconstructed to-be-estimated pixel; according to the reconstructed seed point and the phasor value of the reconstructed to-be-estimated pixel, obtaining two separate images having predetermined components.
    Type: Application
    Filed: December 30, 2015
    Publication date: January 10, 2019
    Applicant: Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences
    Inventors: Hairong Zheng, Xin Liu, Chuanli Cheng, Chao Zou
  • Publication number: 20180369815
    Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity and a ultrasonic emission device, wherein the microcavity is used to accommodate a solution containing particles, the ultrasonic emission device is used to emit ultrasound, and characterized in further comprising a phononic crystal plate placed in the microcavity, wherein the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.
    Type: Application
    Filed: October 10, 2015
    Publication date: December 27, 2018
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Hairong ZHENG, Fwi LI, Felyan CAI, Long MENG, Chen WANG, Chengxiang ZHANG, Weibao QIU, Yongchuan LI, Fei YAN, Lili NIU, Liufeng GENG, Chaowei XU
  • Publication number: 20180267125
    Abstract: A magnetic resonance vessel wall imaging method and device. The method comprises: applying a set pulse sequence into an imaging region, wherein the set pulse sequence comprises, in chronological order, a Delay Alternating with Nutation for Tailored Excitation (DANTE) pulse train, a variable flip angle train of a three-dimensional fast spin echo (SPACE), and a flip-down pulse train (S110); acquiring a magnetic resonance signal generated in the imaging region, and reconstructing a magnetic resonance images of the vessel wall in the imaging region according to the magnetic resonance signal (S120). By adding the flip-down pulse train behind the variable flip angle train of the three-dimensional fast spin echo (SPACE), the cerebrospinal fluid signals of the whole brain can be further suppressed effectively and uniformly, and the DANTE pulse train promotes the vessel wall imaging of the head and neck jointing portion.
    Type: Application
    Filed: May 22, 2018
    Publication date: September 20, 2018
    Inventors: Lei ZHANG, Yiu-Cho CHUNG, Xin LIU, Xiaoqing HU, Hairong ZHENG
  • Patent number: 10018698
    Abstract: Disclosed is a magnetic resonance rapid parameter imaging method and system. The method comprises: obtaining a target undersampled magnetic resonance signal (S10); obtaining prior information of a parameter model (S20); performing sequence reconstruction of a target image according to the undersampled magnetic resonance signal and the prior information to obtain a target image sequence (S30); and substituting the target image sequence into the parameter estimation model to obtain object parameters and to generate parametric images (S40).
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: July 10, 2018
    Assignee: Shenzhen Institutes Of Advanced Technology Chinese Academy Of Sciences
    Inventors: Xi Peng, Dong Liang, Xin Liu, Hairong Zheng
  • Publication number: 20170363702
    Abstract: The application provides a method, apparatus and computer program product for denoising a magnetic resonance diffusion tensor, wherein the method comprises: collecting data of K space; calculating a maximum likelihood estimator of a diffusion tensor according to the collected data of K space; calculating a maximum posterior probability estimator of the diffusion tensor by using sparsity of the diffusion tensor and sparsity of a diffusion parameter and taking the calculating maximum likelihood estimator as an initial value; and calculating the diffusion parameter according to the calculated maximum posterior probability estimator. The application solves the technical problem in the prior art of how to realize high precision denoising of diffusion tensor while not increasing scanning time and affecting spatial resolution, achieves the technical effects of effectively suppressing noises in the diffusion tensor and improving the estimation accuracy of the diffusion tensor.
    Type: Application
    Filed: June 9, 2017
    Publication date: December 21, 2017
    Inventors: Xi PENG, Dong LIANG, Xin LIU, Hairong ZHENG
  • Publication number: 20170291044
    Abstract: An ultrasound deep brain stimulation method and system, the ultrasound deep brain stimulation method comprises: medically imaging a head of an animal or a human being, to generate image data; creating a head 3D digital model according to the image data; creating a 3D digital model of an ultrasound transducer array according to structure, density and acoustic parameters information of the ultrasound transducer array; generating a first ultrasound transmitting sequence according to the head 3D digital model, the 3D digital model of the ultrasound transducer array, structure, density and acoustic parameters of the skull and brain tissues, and structure, density and acoustic parameters of the ultrasound transducer array; and controlling the ultrasound transducer array to transmit ultrasound waves in accordance with the first ultrasound transmitting sequence, to implement ultrasound deep brain stimulation to the brain nucleus to be stimulated.
    Type: Application
    Filed: June 22, 2017
    Publication date: October 12, 2017
    Inventors: Hairong ZHENG, Lili NIU, Congzhi WANG, Ming QIAN, Yang XIAO, Long MENG