Patents by Inventor Haishan LUO

Haishan LUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250052140
    Abstract: A method for performing a polymer flood of a hydrocarbon-bearing, subterranean reservoir (5) includes (a) injecting a polymer solution from an injection well (32) into the subterranean reservoir to form a polymer slug (44) in the subterranean reservoir, wherein the polymer slug has a leading front (46) and a trailing rear (48), and an S-shaped graded viscosity profile which decreases convexly in viscosity from the front of the polymer slug to an inflection point and concavely in viscosity from the inflection point to the rear of the polymer slug, (b) injecting an aqueous solution (50) from the injection well into the subterranean reservoir following (a) to displace the polymer slug through the subterranean reservoir.
    Type: Application
    Filed: December 21, 2022
    Publication date: February 13, 2025
    Applicant: TOTALENERGIES E&P RESEARCH & TECHNOLOGY USA, LLC
    Inventors: Stephane Jouenne, Alexandra Klimenko, Khalid Mateen, Kun Ma, Haishan Luo
  • Publication number: 20240269276
    Abstract: The present invention relates to a specific binding protein targeting PD-L1 and CD73, wherein the specific binding protein is capable of specifically binding to PD-L1 and/or a fragment thereof, and CD73 and/or a fragment thereof. The present invention further relates to use of the specific binding protein in the treatment, prevention and/or diagnosis of diseases such as immune diseases, acute and chronic inflammatory diseases, and tumor diseases.
    Type: Application
    Filed: May 24, 2022
    Publication date: August 15, 2024
    Inventors: Qianqian Shan, Xuekun Zhang, Xin Gan, Haishan Luo, Lei Shi, Yongqiang Wang, Xingxing Jia, Rongchao Wang, Yiping Rong
  • Publication number: 20240034792
    Abstract: Provided are an antigen binding protein capable of binding to PD-1 and a fusion protein thereof, and corresponding preparation method therefor and the use thereof. The fusion protein is capable of targeting PD-1 and CD73.
    Type: Application
    Filed: July 15, 2021
    Publication date: February 1, 2024
    Inventors: Haishan LUO, Qianqian SHAN, Yongqiang WANG, Xuekun ZHANG, Lei SHI, Yun ZHANG, Chuchu ZHAO, Wei ZHOU, Xin GAN
  • Publication number: 20230322953
    Abstract: Disclosed is a binding protein having at least two protein functional regions, the binding protein comprising a protein functional region A and a protein functional region B; the protein functional region A and the protein functional region B target different antigens or epitopes, the protein functional region A is a Fab or a scFv structure, the protein functional region B is a VH structure, and there are one or more of each of the protein functional region A and the protein functional region B. A multi-specific binding protein has a smaller molecular weight, fewer polypeptide chains, and a simpler structure. By means of different structure types, relative positions, binding valence and other parameters, the functional activities for different targets can be adjusted, and then different combinations of activities can be designed so as to meet the needs of different dose combinations of clinical combinations.
    Type: Application
    Filed: June 29, 2021
    Publication date: October 12, 2023
    Applicant: HARBOUR BIOMED (SHANGHAI) CO., LTD
    Inventors: Yun HE, Lei SHI, Haishan LUO, Qiang LV, Jinqiu HE, Zenglin PEI, Yongqiang WANG, Chen ZHONG, Bing HUANG, Jianxun ZHAO, Xingxing JIA, Xuekun ZHANG, Chuchu ZHAO, Fei CHEN, Lei NIU
  • Patent number: 10973915
    Abstract: Anti-PD-1 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancers and autoimmune diseases.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 13, 2021
    Assignee: SHANGHAI YUNYI HEALTHCARE AND TECHNOLOGY CO., LTD.
    Inventors: Lile Liu, Xinxiu Yang, Haishan Luo, Hu Liu, Zhengrong Shuai, Jian Wang, Qin Zhong, Qing Duan, Hongzhuan Gu, Tatchi Teddy Yang
  • Patent number: 10889648
    Abstract: Provided herein are anti-PD-L1 antibodies and antigen-binding fragments thereof. Also provided are nucleic acids encoding the antibodies, compositions containing the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancer, infectious diseases and autoimmune diseases.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: January 12, 2021
    Assignee: JIANGSU HYAMAB PHARMACEUTICAL CO., LTD.
    Inventors: Lile Liu, Xinxiu Yang, Haishan Luo, Zhengrong Shuai, Hu Liu, Shaoping Hu, Xiaolan Sun, Hongzhuan Gu, Qing Duan, Tatchi Teddy Yang
  • Publication number: 20190010233
    Abstract: Provided herein are anti-PD-L1 antibodies and antigen-binding fragments thereof. Also provided are nucleic acids encoding the antibodies, compositions containing the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancer, infectious diseases and autoimmune diseases.
    Type: Application
    Filed: December 27, 2016
    Publication date: January 10, 2019
    Inventors: Lile LIU, Xinxiu YANG, Haishan LUO, Zhengrong SHUAI, Hu LIU, Shaoping HU, Xiaolan SUN, Hongzhuan GU, Qing DUAN, Tatchi Teddy YANG
  • Publication number: 20180214548
    Abstract: Anti-PD-1 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancers and autoimmune diseases.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 2, 2018
    Inventors: Lile LIU, Xinxiu YANG, Haishan LUO, Hu LIU, Zhengrong SHUAI, Jian WANG, Qin ZHONG, Qing DUAN, Hongzhuan GU, Tatchi Teddy YANG