Abstract: An electric handle for delivering an implant is disclosed. The electric handle (1) includes an electric control unit (10), a power-driven transmission mechanism (20), a handle housing (30), an outer tube anchor (40) and an inner tube anchor (50), wherein: the electric control unit (10) is operatively coupled to the power-driven transmission mechanism (20) to actuate the power-driven transmission mechanism (20); the power-driven transmission mechanism (20) is supported within the handle housing (30) and moveable together with the outer tube anchor (40); the inner tube anchor (50) is disposed within the handle housing (30) and is configured to hold an inner tube (3) of a delivery system; and the outer tube anchor (40) is configured to hold an outer tube (2) of the delivery system and is fixed to an end of the outer tube (2). A delivery system used especially for delivery of prosthetic valves is also disclosed, including an outer tube (2), an inner tube (3), an expandable implant (4) and the electric handle (1).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: An implant delivery system is disclosed which includes an inner tube assembly, an outer tube assembly and a functional handle. The functional handle includes a threaded rod, a push-pull control member, a casing tube, a displacement tube, an inner tube fixing member, an outer tube fixing member and a stability tube fixing member. The threaded rod extends through a bore of the displacement tube. A fastener of the push-pull control member is able to engage a thread provided on a leading portion of the threaded rod. A trailing portion of the threaded rod is provided with a knob. The push-pull control member includes a fastener, springs and a button. The fastener is able to extend through a slot to engage a thread of the threaded rod in the displacement tube. The springs are configured to cause an automatic locking of the fastener and the threaded rod. The button is provided on the fastener.

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: A method and related system of encoding or re-encoding video is disclosed. In the method, video data comprising a sequence of frames is received. For a respective frame in the sequence of frames, a multi-level frame is generated comprising the respective frame and a plurality of copies of the respective frame. Each copy has an associated video resolution level that is a member of a predefined range of video resolution levels, ranging from a highest video resolution level to a lowest video resolution level. The multi-level frame is encoded.

Abstract: A method of displaying video includes receiving a video bitstream corresponding to a video. The video comprises a sequence of frames having an associated video resolution level. At least a portion of the video bitstream is decoded. A background region of the video is displayed at a first video resolution level and a window region of the video is displayed at a second video resolution level. The second video resolution level is higher than the first video resolution level.

Abstract: The present invention relates to compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to heterocyclic compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase (HDAC) activities.

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: A method provides video from a video data source comprising a sequence of multi-level frames. Each multi-level frame comprises multiple copies of a respective frame. Each copy has an associated video resolution or quality level that is a member of a predefined range of levels that range from a highest level to a lowest level. First video data corresponding to a first portion of a first copy of a respective frame and second video data corresponding to a second portion of a second copy of the respective frame are extracted from the video data source. The video resolution or quality level of the second copy is distinct from that of the first copy. The first and second video data are transmitted to a client device for display. The extracting and transmitting are repeated with respect to successive multi-level frames of the video data source.

Abstract: A method of displaying video includes receiving a video bitstream corresponding to a video. The video comprises a sequence of frames having an associated video resolution level. At least a portion of the video bitstream is decoded. A background region of the video is displayed at a first video resolution level and a window region of the video is displayed at a second video resolution level. The second video resolution level is higher than the first video resolution level.

Abstract: The present invention relates to compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to heterocyclic compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase (HDAC) activities.

Abstract: A method and related system of encoding or re-encoding video is disclosed. In the method, video data comprising a sequence of frames is received. For a respective frame in the sequence of frames, a multi-level frame is generated comprising the respective frame and a plurality of copies of the respective frame. Each copy has an associated video resolution level that is a member of a predefined range of video resolution levels, ranging from a highest video resolution level to a lowest video resolution level. The multi-level frame is encoded.

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to acylurea/sulfonylurea containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities.

Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to biaryl containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities. Formula (I), where Z is a single bond or C1-C4 hydrocarbon, A is an aromatic ring, B is an aromatic ring.

Abstract: Use of a compound of formula (I): wherein each R, which are the same or different, is H or C1–C6 alkyl, and X completes a ring which is a substituted triazine having one of the following formulae (II) to (IV): wherein R? is H or C1–C6 alkyl; or an enol tautomer of a compound of formula (I) in which any of the groups R or R? is hydrogen; in the manufacture of a medicament for use as a protein tyrosine phosphatase (PTP) inhibitor. Formula (I) embraces 2-methylfervenulone, which can be produced by fermentation of a novel microbial strain. Fermentation of the said strain also produces novel precursors to 2-methylfervenulone having utility as prodrugs.