Abstract: A focal adhesion kinase (FAK) inhibitor compound, a composition containing the compound, and a use of the compound. The compound has a good treatment effect on cancer, pulmonary hypertension, and pathological angiogenesis, and has good clinical application prospects.

Abstract: The present invention provides compositions and methods for treating cancers with reduced or absent CDH1 using a RHOA dominant negative polypeptide or biologically active fragment thereof, and/or a nucleic acid encoding a RHOA dominant negative polypeptide or biologically active fragment thereof.

Abstract: The present invention provides a high-strength and high-heat-resistant bio-based polyamide composition, which consists of the following parts of materials by mass: 43.50-89.95% of bio-based polyamide resin slices; 10-50% of reinforcements; 0.01-2% of rare earth compounds; 0.01-1% of copper salt antioxidant combinations; 0.01-1% of free-radical scavengers; 0.01-0.5% of heat-conducting masterbatches; 0.01-1% of stabilizers; and 0-1% of dispersants. The advantage of the present invention is presented in that: the bio-based polyamide resin slice is prepared through a stepwise polycondensation process of pentanediamine and adipic acid, or through a stepwise polycondensation process of pentanediamine, adipic acid and terephthalic acid and the pentanediamine is prepared through fermentation of starch, so the prepared polyamide resin pertains to an environmentally-friendly engineering plastic.

Abstract: The present invention provides compositions and methods for treating cancers with reduced or absent CDH1 using a RHOA dominant negative polypeptide or biologically active fragment thereof, and/or a nucleic acid encoding a RHOA dominant negative polypeptide or biologically active fragment thereof.

Abstract: The present disclosure provides a lens. The lens includes at least two layers of glass wafers, each glass wafer is provided with a lens array including a plurality of lens units, glue is provided around a periphery of each of the lens unit, the lens units of two adjacent layers of glass wafers are correspondingly arranged one to one, and are adhered via the glue, the glass wafer is further provided with an air hole. In the lens provided by the present disclosure, through providing an air hole on the glass wafer of the lens, so that when two adjacent glass wafers are stacked via the glue, air in the sealed space can be exhausted through the air hole, and through filling glue in the air hole of the outermost layer of glass wafer, the sealing effect is achieved, which can avoid packaging defects, and improve product yield.

Abstract: The present disclosure provides a lens. The lens includes at least two layers of glass wafers, each glass wafer is provided with a lens array including a plurality of lens units, glue is provided around a periphery of each of the lens unit, the lens units of two adjacent layers of glass wafers are correspondingly arranged one to one, and are adhered via the glue, the glass wafer is further provided with an air hole. In the lens provided by the present disclosure, through providing an air hole on the glass wafer of the lens, so that when two adjacent glass wafers are stacked via the glue, air in the sealed space can be exhausted through the air hole, and through filling glue in the air hole of the outermost layer of glass wafer, the sealing effect is achieved, which can avoid packaging defects, and improve product yield.