Patents by Inventor Haixia Wang

Haixia Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11716992
    Abstract: A 5A5B6C tricyclic spironolactone derivative is provided with a formula XI: The present invention also relates to its preparation method and its applications in the areas of insecticide, nematicide, fungicide and anti-viral agent. The 5A5B6C tricyclic spironolactone derivatives in the present invention are high-performance, broad-spectrum, low-toxicity and low-ecological risk compounds with a wide range of applications in the areas of agriculture, horticulture, forestry and health.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: August 8, 2023
    Assignee: NANKAI UNIVERSITY
    Inventors: Zhijin Fan, Yujie Zhu, Lai Chen, Shuang Zhou, Xiaofeng Guo, Haixia Wang, Bin Yu, Nailou Zhang, Qifan Wu, Dongyan Yang, Bin Zhao
  • Publication number: 20220267356
    Abstract: Disclosed are compounds of formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cancer or a respiratory inflammatory disease using the same: wherein R1 is selected from hydrogen, —CH3 and —(C?O)CH(R1a)NH2; R1a is C1-C4 alkyl; Y is —(CH2)n— or —(C?O)—; n is an integer selected from 1 and 2; R2 is selected from hydrogen, —CH3 and —(C?X)R4 and R3 is hydrogen or —CH3; or R2 and R3, together with the nitrogen to which they are attached, are linked to form a 6-membered heterocyclic ring; X is NH or O; R4 is —CH3 or —[CH(R4a)]mNH2; m is an integer selected from 0 or 1; and R4a is hydrogen or C1-C6 alkyl.
    Type: Application
    Filed: July 22, 2020
    Publication date: August 25, 2022
    Inventors: Scott Nathan MLYNARSKI, Jason SHIELDS, Sameer KAWATKAR, Qing YE, Haixia WANG, Xiaolan ZHENG, Ray FINLAY, Iain SIMPSON
  • Publication number: 20220092507
    Abstract: A method and apparatus for determining a strategy for medium- and long-term purchase and sale of electricity. The method includes: obtaining a post-transaction position held, a post-transaction total position price, a total load expectation, a total risk electricity fee, and an expected electricity fee according to known information of a target time period; and determining a purchase and sale strategy according to the total risk electricity fee and the expected electricity fee. The purchase and sale strategy with the lowest expected electricity fee is obtained by means of certain constraints on the transaction volume of medium- and long-term contracts and upper limit constraints on risk electricity fees. The expected electricity fee is used as an optimized objective function, and comprehensive optimization is performed on the basis of diversified constraints to obtain the optimal electricity fee strategy with load constraints and controllable risks.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Inventors: Yahui Du, Haixia Wang
  • Publication number: 20210387443
    Abstract: Provided is laminated glass and a preparation method thereof, an electronic device housing, and an electronic device. The laminated glass comprises at least two glass members and at least one adhesive film disposed in a stacked manner, where the glass members and the adhesive film are alternately disposed, wherein decorative layers are provided on surfaces of at least two of the glass members facing toward the adhesive film, and at least two of the decorative layers independently comprise at least one of an etched texture, an optical coating layer, and a pattern layer.
    Type: Application
    Filed: May 16, 2019
    Publication date: December 16, 2021
    Inventors: Haixia WANG, Lan MA, Liang CHEN, Liliang SHI
  • Patent number: 11197858
    Abstract: The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: December 14, 2021
    Assignee: Cardurion Pharmaceuticals, LLC
    Inventors: Nobuyuki Matsunaga, Takashi Nakahata, Yuta Tanaka, Hiroki Takahagi, Yasufumi Miyamoto, Rei Okamoto, Takeshi Yoshikawa, Yoshito Terao, Takafumi Yukawa, Keiko Kakegawa, Yoichi Nishikawa, Terufumi Takagi, Masashi Takahashi, Mallareddy Komandla, Lily Kwok, Joanne Miura, Mark Sabat, Nicholas Scorah, Paul Tanis, John Tyhonas, Phong H. Vu, Haixia Wang, Xiaolun Wang, Junya Shirai, Tomohiro Okawa, Zenyu Shiokawa, Akito Shibuya
  • Patent number: 11166460
    Abstract: The present invention relates to a microbicidal ?-amino acrylic derivative and its preparation method and applications. Based on the principle of pesticide molecular design, the structural reform of the agricultural anti-plant virus activity is carried on lead compounds having the medical anti-coronavirus activity, and a series of ?-amino acrylic derivatives are designed and synthesized, and in particular, ?-amino acrylic derivatives containing piperidine rings are synthesized, and the systematic biological activity screening is carried by using known compounds as positive control compounds, which provide many effective anti-virus leading molecules for the preparation of pesticides, and has positive significance to reduce the pesticide application dosage and protect the environment and ecology.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: November 9, 2021
    Assignee: NANKAI UNIVERSITY
    Inventors: Zhijin Fan, Xiaolin Qian, Jing Xue, Aoben Wu, Huaipu Yang, Liuyong Ma, Bin Yu, Haixia Wang, Nailou Zhang, Qifan Wu, Cenhui Han, Jianyu Jin
  • Publication number: 20210289783
    Abstract: A 5A5B6C tricyclic spironolactone derivative is provided with a formula XI: The present invention also relates to its preparation method and its applications in the areas of insecticide, nematicide, fungicide and anti-viral agent. The 5A5B6C tricyclic spironolactone derivatives in the present invention are high-performance, broad-spectrum, low-toxicity and low-ecological risk compounds with a wide range of applications in the areas of agriculture, horticulture, forestry and health.
    Type: Application
    Filed: March 14, 2018
    Publication date: September 23, 2021
    Inventors: Zhijin Fan, Yujie Zhu, Lai Chen, Shuang Zhou, Xiaofeng Guo, Haixia Wang, Bin Yu, Nailou Zhang, Qifan Wu, Dongyan Yang, Bin Zhao
  • Patent number: 10906880
    Abstract: The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: February 2, 2021
    Assignee: Nankai University
    Inventors: Zhijin Fan, Lai Chen, Xiaofeng Guo, Yujie Zhu, Xiaolin Qian, Liuyong Ma, Nailou Zhang, Haixia Wang, Zhiming Zhang, Jinghua Xu, Yinqi Song
  • Publication number: 20200304162
    Abstract: A metal housing having a ceramic panel and a manufacturing method and an application thereof are provided. The metal housing includes a ceramic panel, a metal frame, and a plastic layer. A periphery of the plastic layer is connected to at least a part of an inner side of the metal frame. The plastic layer has a concave portion. The ceramic panel covers the concave portion and is connected to the plastic layer.
    Type: Application
    Filed: March 31, 2018
    Publication date: September 24, 2020
    Applicant: BYD Company Limited
    Inventors: Peng REN, Shuai ZHU, Haixia WANG, Lan MA, Liang CHEN
  • Publication number: 20200236935
    Abstract: The present invention relates to a microbicidal ?-amino acrylic derivative and its preparation method and applications. Based on the principle of pesticide molecular design, the structural reform of the agricultural anti-plant virus activity is carried on lead compounds having the medical anti-coronavirus activity, and a series of ?-amino acrylic derivatives are designed and synthesized, and in particular, ?-amino acrylic derivatives containing piperidine rings are synthesized, and the systematic biological activity screening is carried by using known compounds as positive control compounds, which provide many effective anti-virus leading molecules for the preparation of pesticides, and has positive significance to reduce the pesticide application dosage and protect the environment and ecology.
    Type: Application
    Filed: May 17, 2017
    Publication date: July 30, 2020
    Inventors: Zhijin Fan, Xiaolin Qian, Jing Xue, Aoben Wu, Huaipu Yang, Liuyong Ma, Bin Yu, Haixia Wang, Nailou Zhang, Qifan Wu, Cenhul Han, Jianyu Jin
  • Publication number: 20200230137
    Abstract: The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: January 27, 2020
    Publication date: July 23, 2020
    Applicant: Cardurion Pharmaceuticals, LLC
    Inventors: Nobuyuki MATSUNAGA, Takashi NAKAHATA, Yuta TANAKA, Hiroki TAKAHAGI, Yasufumi MIYAMOTO, Rei OKAMOTO, Takeshi YOSHIKAWA, Yoshito TERAO, Takafumi YUKAWA, Keiko KAKEGAWA, Yoichi NISHIKAWA, Terufumi TAKAGI, Masashi TAKAHASHI, Mallareddy KOMANDLA, Lily KWOK, Joanne MIURA, Mark SABAT, Nicholas SCORAH, Paul TANIS, John TYHONAS, Phong H. VU, Haixia WANG, Xiaolun WANG, Junya SHIRAI, Tomohiro OKAWA, Zenyu SHIOKAWA, Akito SHIBUYA
  • Publication number: 20200198195
    Abstract: The present invention discloses a 3D glass-metal composite body, a preparing method thereof, and an electronic device. The 3D glass-metal composite body comprises a 3D glass cover plate, a plastic frame body, and a metal frame. The plastic frame body is formed between an edge surface of the 3D glass cover plate and an upper surface of the metal frame. Outer peripheries of the 3D glass cover plate, the plastic frame body, and the metal frame are in smooth transition along curvature of the 3D glass cover plate without steps.
    Type: Application
    Filed: August 17, 2018
    Publication date: June 25, 2020
    Inventors: Peng REN, Lan MA, Liang CHEN, Haixia WANG
  • Patent number: 10543212
    Abstract: The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: January 28, 2020
    Assignee: Cardurion Pharmaceuticals, LLC
    Inventors: Nobuyuki Matsunaga, Takashi Nakahata, Yuta Tanaka, Hiroki Takahagi, Yasufumi Miyamoto, Rei Okamoto, Takeshi Yoshikawa, Yoshito Terao, Takafumi Yukawa, Keiko Kakegawa, Yoichi Nishikawa, Terufumi Takagi, Masashi Takahashi, Mallareddy Komandla, Lily Kwok, Joanne Miura, Mark Sabat, Nicholas Scorah, Paul Tanis, John Tyhonas, Phong H. Vu, Haixia Wang, Xiaolun Wang, Junya Shirai, Tomohiro Okawa, Zenyu Shiokawa, Akito Shibuya
  • Publication number: 20200029466
    Abstract: A liquid-heat-transmission device includes a vapor chamber, a cover, and a channel structure. The cover covers on a surface of the vapor chamber and a flow chamber is defined thereby. A water inlet and a water outlet respectively communicated with the flow chamber are defined on the cover. The channel structure is arranged in the flow chamber. The flow channel structure includes multiple fins arranged between the water inlet and the water outlet and with an interval apart. Each fin is extended in a longitudinal direction on a surface of the vapor chamber and connected to the vapor chamber and the cover. The vapor chamber is attached to a heat source, and a working fluid flows through the flow chamber from the water inlet of the cover and is drained after fully exchanging heat with the vapor chamber.
    Type: Application
    Filed: July 18, 2018
    Publication date: January 23, 2020
    Inventors: Ling LONG, Haixia WANG, Tonghu XIA
  • Publication number: 20200025641
    Abstract: A leak-detectable liquid-heat-transmission device including a heat conductive plate, a cover covering on one surface of the heat conductive plate, and a channel structure disposed in the cover is provided. The channel structure is arranged on the heat conductive plate and the cover. A flow chamber and a leak detecting channel surrounding and isolated from the flow chamber is defined between the cover and the heat conductive plate by the channel structure. An inlet and an outlet respectively communicated with the flow chamber are defined on the cover, and a fluid sensor for detecting the working fluid leaking from the flow chamber is arranged in the leak detecting channel.
    Type: Application
    Filed: July 18, 2018
    Publication date: January 23, 2020
    Inventors: Ling LONG, Haixia WANG, Tonghu XIA
  • Publication number: 20190224190
    Abstract: Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.
    Type: Application
    Filed: April 3, 2019
    Publication date: July 25, 2019
    Inventors: John David Lawson, Mark Sabat, Nicholas Scorah, Christopher Smith, Phong H. Vu, Haixia Wang
  • Patent number: 10307414
    Abstract: Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 4, 2019
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: John David Lawson, Mark Sabat, Nicholas Scorah, Christopher Smith, Phong H. Vu, Haixia Wang
  • Publication number: 20190031627
    Abstract: The present invention is that provided a synthesis method of a series of isothiazole oxime ether-containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.
    Type: Application
    Filed: January 25, 2017
    Publication date: January 31, 2019
    Inventors: Zhijin Fan, Lai Chen, Xiaofeng Guo, Yujie Zhu, Xiaolin Qian, Liuyong Ma, Nailou Zhang, Haixia Wang, Zhiming Zhang, Jinghua Xu, Yinqi Song
  • Publication number: 20190032018
    Abstract: Compositions and methods are described herein for chemically inducing cells that express a single pluripotency transcription factor to change their differentiation state and become cardiac cells, cardiac progenitor cells, cardiomyocytes, or a combination thereof.
    Type: Application
    Filed: October 12, 2018
    Publication date: January 31, 2019
    Inventors: Haixia WANG, Sheng DING
  • Patent number: 10165562
    Abstract: A blind detection method and system for a PDCCH. The method comprises: acquiring PDCCH data; grouping the PDCCH data according to a location identifier of a resource element, and obtaining soft bit data according to each set of PDCCH data after grouping; acquiring control channel soft bit data from the soft bit data; determining DCI data according to the control channel element soft bit data; and acquiring a random access radio network temporary identifier according to the DCI data, to complete blind detection of a PDCCH. The technical solutions in the present application are applicable to a case in which an RNTI of a user is not determined, can ensure accuracy of blind detection of a PDCCH, and greatly reduce a calculation amount and a calculation time.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: December 25, 2018
    Assignee: Datang Linktester Technology Co., Ltd.
    Inventors: Haixia Wang, Yajun Liu, Chunbai Tan