Patents by Inventor Haixia Zhang
Haixia Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12252484Abstract: The present invention relates to compounds of formula (I), wherein R1, R2, R3 and R4 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.Type: GrantFiled: September 6, 2018Date of Patent: March 18, 2025Assignee: Hoffmann-La Roche Inc.Inventors: Fabian Dey, Taishan Hu, Haixia Liu, Hong Shen, Zhiwei Zhang, Wei Zhu
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Publication number: 20250085164Abstract: A wavelength calibration method for a grating spectrometer is provided, including: moving a plurality of characteristic peaks of a calibration light source to a central position of a detector of the spectrometer respectively, and determining a functional relationship between a grating rotation angle of the rotatable grating and a central wavelength; and determining parameters ?, f, a, b, c in the following physical model, the physical model being used to calculate a corresponding wavelength at each pixel within an imaging range of the detector when the central wavelength is determined, ? ? = sin ? ( ? - ? 2 ) + sin ? ( ? + ? 2 + arctan ? ( a ? ( n ? x ) 2 + b ? ( n ? x ) + c f ) ) 1 ? 0 - 6 · m · N wherein ? is the grating rotation angle corresponding to the central wavelength as determined via the functional relationship, ? is built-in angle of the spectrometer, f is a focal distance of the spectrometer, m is grating diffraction order, N is the number oType: ApplicationFiled: July 16, 2024Publication date: March 13, 2025Inventors: Zemin Lei, Fei Tong, Suxia Zhang, Haixia Chen
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Patent number: 12247036Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.Type: GrantFiled: August 22, 2024Date of Patent: March 11, 2025Assignee: Hoffmann-La Roche Inc.Inventors: Jianguo Chen, Lei Guo, Haixia Liu, Hong Shen, Junwei Xi, Weixing Zhang, Dan Zhao, Wei Zhu
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Publication number: 20250074913Abstract: The present invention provides novel compounds having the general formula: wherein ring A, ring B, ring C, bond a, and R1 to R7 are as described herein, or a pharmaceutically acceptable salt thereof, compositions including the compounds and methods of using the compounds.Type: ApplicationFiled: November 14, 2024Publication date: March 6, 2025Applicant: Hoffmann-La Roche Inc.Inventors: Haixia LIU, Yafei LIU, Jianping WANG, Yao WU, Zhiwei ZHANG
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Patent number: 12234232Abstract: Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.Type: GrantFiled: September 23, 2019Date of Patent: February 25, 2025Assignee: SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD.Inventors: Lei Jiang, Jianwen Deng, Zhiyong Feng, Shengyang Liu, Xudong Mao, Ke Shang, Jianyong Shou, Danyi Wu, Xiaoping Xie, Yuan Xu, Haixia Zhao, Jianhua Zhang, Mingwei Zheng
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Patent number: 12191967Abstract: A non-uniform beam spatial modulation method and system applicable to multi-antenna communication and sensing integration; the method includes: finding an ISAC beam that satisfies both sensing performance and communication performance, including: constructing a communication transmitting signal; constructing a communication receiving signal; constructing an upper bound of the integrated communication and sensing spectral efficiency of the non-uniform beam spatial modulation; constructing an objective function of the sensing performance; and finding a candidate beam matrix and a beam activation probability distribution where the spectrum frequency is maximum and the sensing performance is best; and finding a spectral efficiency of non-uniform beam spatial modulation by means of the ISAC beam. Under the condition of meeting the same sensing performance requirement, the spectral efficiency of the present invention is higher.Type: GrantFiled: October 25, 2022Date of Patent: January 7, 2025Assignee: SHAN DONG UNIVERSITYInventors: Shuaishuai Guo, Dingyan Cong, Haixia Zhang
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Patent number: 12005652Abstract: A device for manufacturing a storage container by integrally winding multiple bundles of fibers in a double-layer spiral circumferential direction. The device includes a rotary drive unit and two radial slide drive units provided at two sides of the rotary drive unit, each of the two radial slide drive units is provided with several spiral winding guide wire tubes in a circumferential array and drives the spiral winding guide wire tubes to perform a radial telescopic movement, the rotary drive unit drives the spiral winding guide wire tubes on the two radial slide drive units to perform a rotation movement, the rotary drive unit is connected to the two radial slide drive units by means of brackets, and a rack plate is connected to one side of each of the two radial slide drive units away from the rotary drive unit.Type: GrantFiled: November 14, 2023Date of Patent: June 11, 2024Assignee: TAIYUAN UNIVERSITY OF TECHNOLOGYInventors: Jianguo Liang, Qingxue Huang, Yujie Duan, Yinhui Li, Chunjiang Zhao, Jun Feng, Liping Bian, Haixia Zhang, Yanchun Zhu, Yuqin Xue
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Patent number: 12003032Abstract: A hybrid network antenna includes a reflection plate, a low frequency antenna array, and a dual-beam antenna array. The reflection plate includes a flat member and bending members formed by bending the two ends of the flat member. The low frequency antenna array is arranged on the flat member. The dual-beam antenna array include beam antenna sub-arrays located on both sides of the low frequency antenna array. The beam antenna sub-array on each side of the low frequency array includes a plurality of first high frequency radiating element arrays disposed in intervals along the width direction of the reflection plate. The plurality of high frequency radiating element arrays of each beam antenna sub-array are arranged on the reflection plate in different planes or a common plane.Type: GrantFiled: December 29, 2021Date of Patent: June 4, 2024Assignees: PROSE TECHNOLOGIES (SUZHOU) CO., LTD., PROSE TECHNOLOGIES LLCInventors: He Sun, Shengguang Wang, Zhongcao Yang, Haixia Zhang, Linfeng Sheng
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Patent number: 11943114Abstract: An active edge caching method based on community discovery and weighted federated learning for selecting an optimal caching user and developing an optimal caching strategy; user grouping method based on community discovery is first provided, users are divided into different user groups according to users' mobility and social attributes, degrees of importance of different users are computed in each user group, and most important user is selected as a caching node to provide content distribution services; a content popularity prediction framework based on attention weighted federated learning is provided for combining attention weighted federated learning mechanism with deep learning algorithm to predict future user preferences for different content, so as to improve content popularity prediction accuracy and solve user privacy disclosure; finally, hot content is cached on selected caching users according to prediction results, to achieve goals of reducing network transmission latency and network operation costType: GrantFiled: June 1, 2023Date of Patent: March 26, 2024Assignee: SHANDONG UNIVERSITYInventors: Haixia Zhang, Dongyang Li, Dongfeng Yuan
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Publication number: 20240092038Abstract: A device for manufacturing a storage container by integrally winding multiple bundles of fibers in a double-layer spiral circumferential direction. The device includes a rotary drive unit and two radial slide drive units provided at two sides of the rotary drive unit, each of the two radial slide drive units is provided with several spiral winding guide wire tubes in a circumferential array and drives the spiral winding guide wire tubes to perform a radial telescopic movement, the rotary drive unit drives the spiral winding guide wire tubes on the two radial slide drive units to perform a rotation movement, the rotary drive unit is connected to the two radial slide drive units by means of brackets, and a rack plate is connected to one side of each of the two radial slide drive units away from the rotary drive unit.Type: ApplicationFiled: November 14, 2023Publication date: March 21, 2024Inventors: Jianguo LIANG, Qingxue HUANG, Yujie DUAN, Yinhui LI, Chunjiang ZHAO, Jun FENG, Liping BIAN, Haixia ZHANG, Yanchun ZHU, Yuqin XUE
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Publication number: 20240089811Abstract: A communication connection resuming method, a base station and a computer-readable storage medium are disclosed. The method may include, sending a UE information acquisition request to the source MN, in response to a reception of a radio resource control (RRC) Resume request sent by the UE; acquiring RRC configuration information of the source SN fed back by the source MN; determining a target SN, and sending RRC configuration information to the target SN, to instruct the target SN to complete a configuration according to the RRC configuration information; and resuming a dual-connectivity communication of the UE in cooperation with the target SN with the configuration completed.Type: ApplicationFiled: January 6, 2022Publication date: March 14, 2024Inventor: Haixia ZHANG
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Publication number: 20230327739Abstract: A non-uniform beam spatial modulation method and system applicable to multi-antenna communication and sensing integration; the method includes: finding an ISAC beam that satisfies both sensing performance and communication performance, including: constructing a communication transmitting signal; constructing a communication receiving signal; constructing an upper bound of the integrated communication and sensing spectral efficiency of the non-uniform beam spatial modulation; constructing an objective function of the sensing performance; and finding a candidate beam matrix and a beam activation probability distribution where the spectrum frequency is maximum and the sensing performance is best; and finding a spectral efficiency of non-uniform beam spatial modulation by means of the ISAC beam. Under the condition of meeting the same sensing performance requirement, the spectral efficiency of the present invention is higher.Type: ApplicationFiled: October 25, 2022Publication date: October 12, 2023Inventors: Shuaishuai GUO, Dingyan CONG, Haixia ZHANG
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Publication number: 20230243722Abstract: A blade roller device (100) includes a first blade roll unit (110), a second blade roll unit (120) spaced apart from the first blade roll unit (110), and a first rotate lever (130). The first blade roll unit (110) includes a first slewing mechanism (111) and a first blade roll (112) wound upon the first slewing mechanism (111). The second blade roll unit (120) includes a second slewing mechanism (121) coupled to the first rotate lever (130) and a second blade roll (122) formed by pulling a segment of the first blade roll (112) to the second slewing mechanism (121) and winding the segment of the first blade roll (112) upon the second slewing mechanism (121). A rotation of the first rotate lever (130) in a first direction is capable of pulling the segment of first blade roll (112) to the second slewing mechanism (121).Type: ApplicationFiled: October 30, 2019Publication date: August 3, 2023Inventors: Zheguang FAN, Haixia ZHANG
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Patent number: 11468370Abstract: A communication compression method based on model weight distribution in federated learning, and belongs to the technical field of wireless communication. Based on the existing federated average idea in federated learning, counts the distribution of model weight information to be transmitted between nodes during each communication, then performs scalar quantization and compression through Lloyd-Max quantizer according to their distribution characteristics, then encodes with Huffman coding method, and finally sends the codes to the target node, thereby the minimum mean square quantization error is realized and the number of bits required for communication is reduced.Type: GrantFiled: March 7, 2022Date of Patent: October 11, 2022Assignee: SHANDONG UNIVERSITYInventors: Shuaishuai Guo, Shuheng Lv, Haixia Zhang
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Publication number: 20220123482Abstract: A hybrid network antenna includes a reflection plate, a low frequency antenna array, and a dual-beam antenna array. The reflection plate includes a flat member and bending members formed by bending the two ends of the flat member. The low frequency antenna array is arranged on the flat member. The dual-beam antenna array include beam antenna sub-arrays located on both sides of the low frequency antenna array. The beam antenna sub-array on each side of the low frequency array includes a plurality of first high frequency radiating element arrays disposed in intervals along the width direction of the reflection plate. The plurality of high frequency radiating element arrays of each beam antenna sub-array are arranged on the reflection plate in different planes or a common plane.Type: ApplicationFiled: December 29, 2021Publication date: April 21, 2022Inventors: He Sun, Shengguang WANG, Zhongcao YANG, Haixia ZHANG, Linfeng SHENG
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Patent number: 10712893Abstract: A single-surface position sensor and a positioning method thereof are disclosed.Type: GrantFiled: February 11, 2015Date of Patent: July 14, 2020Assignee: PEKING UNIVERSITYInventors: Haixia Zhang, Mayue Shi, Haotian Chen, Jinxin Zhang, Mengdi Han, Zongming Su, Bo Meng, Xiaoliang Cheng
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Patent number: 10193472Abstract: A single friction surface microgenerator and a method of manufacturing the same are described. The microgenerator comprises an insulating substrate with a surface-friction-structured layer on its upper surface and a first induction electrode and a second induction electrode on its lower surface. The first induction electrode is located to correspond to the surface-friction-structured layer that is used as a friction surface while the second induction electrode is located periphery of the first induction electrode and insulatedly spaced from the first induction electrode. The single friction surface microgenerator according to the present disclosure has a wide usage and the method of manufacturing the same may be performed through a simply and high-effective production process, processed at low cost, and may achieve high yield.Type: GrantFiled: March 13, 2013Date of Patent: January 29, 2019Assignee: PEKING UNIVERSITYInventors: Haixia Zhang, Bo Meng, Wei Tang
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Publication number: 20180267650Abstract: A single-surface position sensor and a positioning method thereof are disclosed.Type: ApplicationFiled: February 11, 2015Publication date: September 20, 2018Inventors: Haixia ZHANG, Mayue SHI, Haotian CHEN, Jinxin ZHANG, Mengdi HAN, Zongming SU, Bo MENG, Xiaoliang CHENG
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Publication number: 20180169177Abstract: A polypeptide is provided specifically binding to CD34 molecule and use thereof, the polypeptide is selected from at least one of polypeptide 17 and polypeptide 19, amino acid sequences of the polypeptide 17 and the polypeptide 19 are as shown in SEQ ID NO: 1 and SEQ ID NO: 2 in sequence listing. The polypeptide provided by the present application can specifically bind to CD34, and can be produced by artificial synthesis or genetic engineering method. Compared with antibody, the polypeptide provided by the present invention has characteristics such as low molecular weight, easy preparation and less immunological rejection; and it has little toxic side-effects, its binding to the CD34+ cell won't obviously kill the target cell and inhibit its proliferation. The polypeptide provided by the present invention can be used as markers for CD34 positive expression cells, and also can be used as substitute of immunofluorescence CD34 antibody.Type: ApplicationFiled: September 22, 2015Publication date: June 21, 2018Inventors: HUA WANG, LONG ZHAO, HAIXIA ZHANG, YAN ZHANG
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Patent number: 9825558Abstract: The disclosure discloses a vibration generator and a stacked-structure generator. The vibration generator includes an arched friction unit 1 and an arched friction unit 2. An concave inner surface of the arched friction unit 1 and an concave inner surface of the arched friction unit 2 are located opposite to each other as friction surfaces; and, the arched friction units 1 and 2 are provided with electrodes at convex outer surfaces thereof, which are concurrently served as supporting layers. The stacked-structure generator includes a plurality of the vibration generators, and several sets of a first geometrically complementary-shaped friction unit, which matches the electrode of the vibration generator that is concurrently served as the supporting layer, and a second geometrically complementary-shaped friction unit.Type: GrantFiled: February 5, 2013Date of Patent: November 21, 2017Assignee: PEKING UNIVERSITYInventors: Haixia Zhang, Wei Tang, Bo Meng