Patents by Inventor Haixun Guo

Haixun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11160887
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: November 2, 2021
    Assignee: UNM Rainforest Innovations
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 10992871
    Abstract: A method and an apparatus for protecting a device under powerful light are disclosed. It is determined whether there is a powerful light source in an image captured by a camera device based on the number of target pixels (pixels whose gray values are larger than the first preset threshold) in the image. If so, it is indicated that the photosensitive element in the camera device is aligned with the powerful light source. In this case, the light avoidance instruction is sent, so as to cause a photosensitive element of the camera device to avoid the light source, thereby reducing the damage caused by the powerful light to the photosensitive element in the camera device.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: April 27, 2021
    Inventors: Wei Yang, Haixun Guo, Qiyi Song, Jie Tang
  • Publication number: 20200123216
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Application
    Filed: September 27, 2019
    Publication date: April 23, 2020
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20190364218
    Abstract: A method and an apparatus for protecting a device under powerful light are disclosed. It is determined whether there is a powerful light source in an image captured by a camera device based on the number of target pixels (pixels whose gray values are larger than the first preset threshold) in the image. If so, it is indicated that the photosensitive element in the camera device is aligned with the powerful light source. In this case, the light avoidance instruction is sent, so as to cause a photosensitive element of the camera device to avoid the light source, thereby reducing the damage caused by the powerful light to the photosensitive element in the camera device.
    Type: Application
    Filed: January 15, 2018
    Publication date: November 28, 2019
    Inventors: Wei Yang, Haixun Guo, Qiyi Song, Jie Tang
  • Patent number: 10464985
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: November 5, 2019
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20190282716
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Application
    Filed: February 5, 2019
    Publication date: September 19, 2019
    Inventors: YUBIN MIAO, HAIXUN GUO
  • Patent number: 10265425
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: April 23, 2019
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20190106474
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Application
    Filed: July 19, 2018
    Publication date: April 11, 2019
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 9955074
    Abstract: Disclosed is a target tracking method for an intelligent tracking high speed dome, comprising: in the process of target tracking, when the position coordinates of a newly selected target in the acquired tracking image are received, matching the position coordinates of the newly selected target in the tracking image, using the target corresponding to the position coordinates of the newly selected target in the tracking image as a current target, and extracting the characteristics of the current target; tracking the current target according to the characteristics thereof, and updating in real time the position coordinates of the current target in the tracking image; converting the updated position coordinates of the current target into speed dome identifiable horizontal rotation value P, vertical rotation value T and magnification factor value Z; adjusting in real time the magnification factor of the speed dome, and controlling in real time the rotation of the speed dome.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: April 24, 2018
    Assignee: HANGZHOU HIKVISION DIGITAL TECHNOLOGY CO., LTD.
    Inventors: Limeng Zhou, Haixun Guo, Caihan Shen, Xiaochen Quan
  • Publication number: 20160375158
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Application
    Filed: June 20, 2016
    Publication date: December 29, 2016
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 9493537
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: November 15, 2016
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 9393330
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: July 19, 2016
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20150239952
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Application
    Filed: February 24, 2015
    Publication date: August 27, 2015
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20150229841
    Abstract: Disclosed is a target tracking method for an intelligent tracking high speed dome, comprising: in the process of target tracking, when the position coordinates of a newly selected target in the acquired tracking image are received, matching the position coordinates of the newly selected target in the tracking image, using the target corresponding to the position coordinates of the newly selected target in the tracking image as a current target, and extracting the characteristics of the current target; tracking the current target according to the characteristics thereof, and updating in real time the position coordinates of the current target in the tracking image; converting the updated position coordinates of the current target into speed dome identifiable horizontal rotation value P, vertical rotation value T and magnification factor value Z; adjusting in real time the magnification factor of the speed dome according to the value Z, and controlling in real time the rotation of the speed dome according to th
    Type: Application
    Filed: September 17, 2013
    Publication date: August 13, 2015
    Applicant: Hangzhou Hikvision Digital Technology Co., Ltd.
    Inventors: Limeng Zhou, Haixun Guo, Caihan Shen, Xiaochen Quan
  • Publication number: 20150157747
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Application
    Filed: February 13, 2015
    Publication date: June 11, 2015
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 8986651
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: March 24, 2015
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20140147385
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 29, 2014
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 8603435
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. The present invention represents a step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: December 10, 2013
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20120225016
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Application
    Filed: November 30, 2010
    Publication date: September 6, 2012
    Inventors: Yubin Miao, Haixun Guo
  • Publication number: 20110033380
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.
    Type: Application
    Filed: January 12, 2009
    Publication date: February 10, 2011
    Applicant: STC UNM
    Inventors: Yubin Mlao, Haixun Guo