Patents by Inventor Haixun Guo
Haixun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11160887Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: GrantFiled: February 5, 2019Date of Patent: November 2, 2021Assignee: UNM Rainforest InnovationsInventors: Yubin Miao, Haixun Guo
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Patent number: 10992871Abstract: A method and an apparatus for protecting a device under powerful light are disclosed. It is determined whether there is a powerful light source in an image captured by a camera device based on the number of target pixels (pixels whose gray values are larger than the first preset threshold) in the image. If so, it is indicated that the photosensitive element in the camera device is aligned with the powerful light source. In this case, the light avoidance instruction is sent, so as to cause a photosensitive element of the camera device to avoid the light source, thereby reducing the damage caused by the powerful light to the photosensitive element in the camera device.Type: GrantFiled: January 15, 2018Date of Patent: April 27, 2021Inventors: Wei Yang, Haixun Guo, Qiyi Song, Jie Tang
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Publication number: 20200123216Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: ApplicationFiled: September 27, 2019Publication date: April 23, 2020Inventors: Yubin Miao, Haixun Guo
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Publication number: 20190364218Abstract: A method and an apparatus for protecting a device under powerful light are disclosed. It is determined whether there is a powerful light source in an image captured by a camera device based on the number of target pixels (pixels whose gray values are larger than the first preset threshold) in the image. If so, it is indicated that the photosensitive element in the camera device is aligned with the powerful light source. In this case, the light avoidance instruction is sent, so as to cause a photosensitive element of the camera device to avoid the light source, thereby reducing the damage caused by the powerful light to the photosensitive element in the camera device.Type: ApplicationFiled: January 15, 2018Publication date: November 28, 2019Inventors: Wei Yang, Haixun Guo, Qiyi Song, Jie Tang
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Patent number: 10464985Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: GrantFiled: July 19, 2018Date of Patent: November 5, 2019Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Publication number: 20190282716Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: ApplicationFiled: February 5, 2019Publication date: September 19, 2019Inventors: YUBIN MIAO, HAIXUN GUO
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Patent number: 10265425Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: GrantFiled: June 20, 2016Date of Patent: April 23, 2019Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Publication number: 20190106474Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: ApplicationFiled: July 19, 2018Publication date: April 11, 2019Inventors: Yubin Miao, Haixun Guo
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Patent number: 9955074Abstract: Disclosed is a target tracking method for an intelligent tracking high speed dome, comprising: in the process of target tracking, when the position coordinates of a newly selected target in the acquired tracking image are received, matching the position coordinates of the newly selected target in the tracking image, using the target corresponding to the position coordinates of the newly selected target in the tracking image as a current target, and extracting the characteristics of the current target; tracking the current target according to the characteristics thereof, and updating in real time the position coordinates of the current target in the tracking image; converting the updated position coordinates of the current target into speed dome identifiable horizontal rotation value P, vertical rotation value T and magnification factor value Z; adjusting in real time the magnification factor of the speed dome, and controlling in real time the rotation of the speed dome.Type: GrantFiled: September 17, 2013Date of Patent: April 24, 2018Assignee: HANGZHOU HIKVISION DIGITAL TECHNOLOGY CO., LTD.Inventors: Limeng Zhou, Haixun Guo, Caihan Shen, Xiaochen Quan
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Publication number: 20160375158Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: ApplicationFiled: June 20, 2016Publication date: December 29, 2016Inventors: Yubin Miao, Haixun Guo
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Patent number: 9493537Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: GrantFiled: February 24, 2015Date of Patent: November 15, 2016Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Patent number: 9393330Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: GrantFiled: October 30, 2013Date of Patent: July 19, 2016Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Publication number: 20150239952Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: ApplicationFiled: February 24, 2015Publication date: August 27, 2015Inventors: Yubin Miao, Haixun Guo
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Publication number: 20150229841Abstract: Disclosed is a target tracking method for an intelligent tracking high speed dome, comprising: in the process of target tracking, when the position coordinates of a newly selected target in the acquired tracking image are received, matching the position coordinates of the newly selected target in the tracking image, using the target corresponding to the position coordinates of the newly selected target in the tracking image as a current target, and extracting the characteristics of the current target; tracking the current target according to the characteristics thereof, and updating in real time the position coordinates of the current target in the tracking image; converting the updated position coordinates of the current target into speed dome identifiable horizontal rotation value P, vertical rotation value T and magnification factor value Z; adjusting in real time the magnification factor of the speed dome according to the value Z, and controlling in real time the rotation of the speed dome according to thType: ApplicationFiled: September 17, 2013Publication date: August 13, 2015Applicant: Hangzhou Hikvision Digital Technology Co., Ltd.Inventors: Limeng Zhou, Haixun Guo, Caihan Shen, Xiaochen Quan
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Publication number: 20150157747Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: ApplicationFiled: February 13, 2015Publication date: June 11, 2015Inventors: Yubin Miao, Haixun Guo
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Patent number: 8986651Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: GrantFiled: November 30, 2010Date of Patent: March 24, 2015Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Publication number: 20140147385Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: ApplicationFiled: October 30, 2013Publication date: May 29, 2014Inventors: Yubin Miao, Haixun Guo
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Patent number: 8603435Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. The present invention represents a step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: GrantFiled: January 12, 2009Date of Patent: December 10, 2013Assignee: STC.UNMInventors: Yubin Miao, Haixun Guo
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Publication number: 20120225016Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.Type: ApplicationFiled: November 30, 2010Publication date: September 6, 2012Inventors: Yubin Miao, Haixun Guo
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Publication number: 20110033380Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma.Type: ApplicationFiled: January 12, 2009Publication date: February 10, 2011Applicant: STC UNMInventors: Yubin Mlao, Haixun Guo